{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:01:48Z","timestamp":1787238108717,"version":"build-2736575974"},"reference-count":72,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T00:00:00Z","timestamp":1744329600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fogarty International centre of the National Institutes of Health"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["HIV Research & Clinical Practice"],"published-print":{"date-parts":[[2025,12,31]]},"DOI":"10.1080\/25787489.2025.2490774","type":"journal-article","created":{"date-parts":[[2025,4,12]],"date-time":"2025-04-12T02:36:56Z","timestamp":1744425416000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":6,"title":["Prevalence and predictors of virological failure among the people living with HIV on antiretroviral treatment in East Africa: evidence from a systematic review with meta-analysis and meta-regression of published studies from 2016 to 2023"],"prefix":"10.1080","volume":"26","author":[{"given":"Maria Magdalene","family":"Namaganda","sequence":"first","affiliation":[{"name":"Department of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University","place":["Kampala, Uganda"]},{"name":"The African Center of Excellence in Bioinformatics and Data-Intensive Science (ACE)","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussein","family":"Mukasa Kafeero","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Habib Medical School, Faculty of Health Sciences, Islamic University in Uganda","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce","family":"Nakatumba Nabende","sequence":"additional","affiliation":[{"name":"Department of Computer Science, School of Computing and Information Technology, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Patrick","family":"Kateete","sequence":"additional","affiliation":[{"name":"Department of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Batte","sequence":"additional","affiliation":[{"name":"Department of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misaki","family":"Wanyengera","sequence":"additional","affiliation":[{"name":"Department of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daudi","family":"Jjingo","sequence":"additional","affiliation":[{"name":"The African Center of Excellence in Bioinformatics and Data-Intensive Science (ACE)","place":["Kampala, Uganda"]},{"name":"Department of Computer Science, School of Computing and Information Technology, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moses","family":"Joloba","sequence":"additional","affiliation":[{"name":"Department of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Kivunike","sequence":"additional","affiliation":[{"name":"Department of Computer Science, School of Computing and Information Technology, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac","family":"Ssewanyana","sequence":"additional","affiliation":[{"name":"Uganda National Health Laboratory Services","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunus","family":"Miya","sequence":"additional","affiliation":[{"name":"The AIDS Support Organization (TASO)","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darius","family":"Kato","sequence":"additional","affiliation":[{"name":"The AIDS Support Organization (TASO)","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simple","family":"Ouma","sequence":"additional","affiliation":[{"name":"The AIDS Support Organization (TASO)","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick Elishama","family":"Kakembo","sequence":"additional","affiliation":[{"name":"Department of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University","place":["Kampala, Uganda"]},{"name":"The African Center of Excellence in Bioinformatics and Data-Intensive Science (ACE)","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Kanyerezi","sequence":"additional","affiliation":[{"name":"The African Center of Excellence in Bioinformatics and Data-Intensive Science (ACE)","place":["Kampala, Uganda"]},{"name":"Uganda National Health Laboratory Services","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jupiter Marina","family":"Kabahiita","sequence":"additional","affiliation":[{"name":"Department of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahad","family":"Muwanda","sequence":"additional","affiliation":[{"name":"Department of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University","place":["Kampala, Uganda"]},{"name":"Department of Medical Microbiology, Habib Medical School, Faculty of Health Sciences, Islamic University in Uganda","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Mboowa","sequence":"additional","affiliation":[{"name":"Department of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University","place":["Kampala, Uganda"]},{"name":"The African Center of Excellence in Bioinformatics and Data-Intensive Science (ACE)","place":["Kampala, Uganda"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,4,11]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/17441692.2020.1851743"},{"key":"e_1_3_2_3_1","volume-title":"Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach","author":"WHO","year":"2016","unstructured":"WHO. WHO guidelines approved by the guidelines review committee. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach. World Health Organization; 2016. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK374318\/"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000002983"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-017-0567-7"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/v15081732"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30702-8"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.121980.1"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000002689"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-3852-3"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000002898"},{"key":"e_1_3_2_12_1","volume-title":"Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach","author":"World Health Organization","year":"2016","unstructured":"World Health Organization. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach; 2016 [cited October 2023]. Available from: https:\/\/www.who.int\/publications\/i\/item\/9789241549684"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.4314\/ahs.v21i1.34"},{"key":"e_1_3_2_14_1","unstructured":"Wells GA Wells G Shea B et\u00a0al. The Newcastle-Ottawa scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. 2014. https:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/nosgen.pdf"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.2307\/2533446"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7109.629"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-14-109"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.3758\/s13428-013-0361-y"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-3934-2"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkw051"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0257204"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0289095"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/23259582221111080"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkz266"},{"key":"e_1_3_2_25_1","first-page":"73","article-title":"Virological and immunological antiretroviral treatment failure and predictors among HIV positive adult and adolescent clients in southeast Ethiopia","volume":"14","author":"Mamo A","year":"2022","unstructured":"Mamo A, Assefa T, Negash W, et\u00a0al. Virological and immunological antiretroviral treatment failure and predictors among HIV positive adult and adolescent clients in southeast Ethiopia. HIV AIDS. 2022;14:73\u201385.","journal-title":"HIV AIDS"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0232649"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-020-05177-2"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx188"},{"key":"e_1_3_2_29_1","first-page":"e0275204","volume-title":"PLoS one","author":"Andarge DE","year":"2022","unstructured":"Andarge DE, Hailu HE, Menna T. Incidence, survival time and associated factors of virological failure among adult HIV\/AIDS patients on first line antiretroviral therapy in St. Paul\u2019s hospital millennium medical college-a retrospective cohort study. PLoS one. 2022;17(10):e0275204."},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-3924-4"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-022-07797-2"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkz261"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/piaa030"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000003361"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2018-053854"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.916454"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0266580"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.134903.1"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000025763"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0244066"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/hiv.13446"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-020-05124-1"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-022-03610-y"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0b013e328331dea5"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiaa683"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-024-20013-x"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-020-01524-1"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001273"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/s42269-024-01248-5"},{"key":"e_1_3_2_50_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2024-087569"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000000580"},{"key":"e_1_3_2_52_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgph.0004121"},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000002979"},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(20)30241-1"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw645"},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.2015.1068117"},{"key":"e_1_3_2_57_1","doi-asserted-by":"publisher","DOI":"10.2217\/hiv.09.2"},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-023-04103-2"},{"key":"e_1_3_2_59_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16020281"},{"key":"e_1_3_2_60_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-024-10736-3"},{"key":"e_1_3_2_61_1","doi-asserted-by":"publisher","DOI":"10.4314\/mmj.v22i2.58794"},{"key":"e_1_3_2_62_1","volume-title":"Prevalence and factors associated with non-adherence to antiretroviral therapy in HIV patients at Kibungo referral hospital, in Rwanda","author":"Niyonsenga PM","unstructured":"Niyonsenga PM, Habimana A, Nsanzabera C. Prevalence and factors associated with non-adherence to antiretroviral therapy in HIV patients at Kibungo referral hospital, in Rwanda. 2025; medRxiv. https:\/\/www.medrxiv.org\/content\/10.1101\/2025.01.02.25319892v1."},{"key":"e_1_3_2_63_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540121.2010.507739"},{"key":"e_1_3_2_64_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0227572"},{"key":"e_1_3_2_65_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12981-023-00572-6"},{"key":"e_1_3_2_66_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-3724-x"},{"key":"e_1_3_2_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-30804-8"},{"key":"e_1_3_2_68_1","doi-asserted-by":"publisher","DOI":"10.4102\/sajhivmed.v23i1.1343"},{"key":"e_1_3_2_69_1","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0000000000000732"},{"key":"e_1_3_2_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(18)30647-9"},{"key":"e_1_3_2_71_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40272-016-0210-4"},{"key":"e_1_3_2_72_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0272405"},{"key":"e_1_3_2_73_1","doi-asserted-by":"publisher","DOI":"10.1080\/17441692.2020.1851386"}],"container-title":["HIV Research & Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/25787489.2025.2490774","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T06:29:07Z","timestamp":1766039347000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/25787489.2025.2490774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,11]]},"references-count":72,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12,31]]}},"alternative-id":["10.1080\/25787489.2025.2490774"],"URL":"https:\/\/doi.org\/10.1080\/25787489.2025.2490774","relation":{},"ISSN":["2578-7489","2578-7470"],"issn-type":[{"value":"2578-7489","type":"print"},{"value":"2578-7470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,11]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=yhct21","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=yhct21","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2024-12-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-01","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2490774"}}