{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:05:00Z","timestamp":1792793100087,"version":"4.5.0"},"reference-count":65,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T00:00:00Z","timestamp":1778889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20220155"],"award-info":[{"award-number":["BK20220155"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Natural Science Foundation of China General Program","award":["32372296"],"award-info":[{"award-number":["32372296"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Top Talent Support Program for young and middle-aged people of Wuxi Health Committee","award":["BJ2023052"],"award-info":[{"award-number":["BJ2023052"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Gut Microbes Reports"],"published-print":{"date-parts":[[2026,12,31]]},"DOI":"10.1080\/29933935.2026.2669712","type":"journal-article","created":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T10:23:20Z","timestamp":1778927000000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":3,"title":["<i>Limosilactobacillus fermentum<\/i>\n                    CCFM1126 attenuates osteoporosis by modulating the gut microbiota composition and fecal metabolites: A randomized, double-blind, placebo-controlled clinical trial"],"prefix":"10.1080","volume":"3","author":[{"given":"Yaru","family":"Liu","sequence":"first","affiliation":[{"name":"Wuxi Institute for Specialized Nutrition and Health, Co., Ltd.","place":["Wuxi, China"]},{"name":"School of Food Science and Technology, State Key Laboratory of Food Science and Resources, Jiangnan University","place":["Wuxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiani","family":"Pan","sequence":"additional","affiliation":[{"name":"Wuxi Institute for Specialized Nutrition and Health, Co., Ltd.","place":["Wuxi, China"]},{"name":"School of Food Science and Technology, State Key Laboratory of Food Science and Resources, Jiangnan University","place":["Wuxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leilei","family":"Yu","sequence":"additional","affiliation":[{"name":"Wuxi Institute for Specialized Nutrition and Health, Co., Ltd.","place":["Wuxi, China"]},{"name":"School of Food Science and Technology, State Key Laboratory of Food Science and Resources, Jiangnan University","place":["Wuxi, China"]},{"name":"School of Food Science and Engineering, Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Hainan University","place":["Haikou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Food Science and Technology, State Key Laboratory of Food Science and Resources, Jiangnan University","place":["Wuxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengcheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Food Science and Technology, State Key Laboratory of Food Science and Resources, Jiangnan University","place":["Wuxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingwei","family":"Yao","sequence":"additional","affiliation":[{"name":"Wuxi Institute for Specialized Nutrition and Health, Co., Ltd.","place":["Wuxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingxing","family":"Chen","sequence":"additional","affiliation":[{"name":"Wuxi Institute for Specialized Nutrition and Health, Co., Ltd.","place":["Wuxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuesong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Affiliated Hospital of Jiangnan University","place":["Wuxi, China"]},{"name":"Wuxi School of Medicine, Jiangnan University","place":["Wuxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxin","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Food Science and Technology, State Key Laboratory of Food Science and Resources, Jiangnan University","place":["Wuxi, China"]},{"name":"International Joint Research Laboratory for Probiotics at Jiangnan University","place":["Wuxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengwei","family":"Tian","sequence":"additional","affiliation":[{"name":"School of Food Science and Technology, State Key Laboratory of Food Science and Resources, Jiangnan University","place":["Wuxi, China"]},{"name":"International Joint Research Laboratory for Probiotics at Jiangnan University","place":["Wuxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qixiao","family":"Zhai","sequence":"additional","affiliation":[{"name":"School of Food Science and Technology, State Key Laboratory of Food Science and Resources, Jiangnan University","place":["Wuxi, China"]},{"name":"International Joint Research Laboratory for Probiotics at Jiangnan University","place":["Wuxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Food Science and Technology, State Key Laboratory of Food Science and Resources, Jiangnan University","place":["Wuxi, China"]},{"name":"International Joint Research Laboratory for Probiotics at Jiangnan University","place":["Wuxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,5,16]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp2307353"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.1083685"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15071694"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2021.1989374"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqy122"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-019-0170-1"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani12151946"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2021.11.030"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2020.112313"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-016-3561-3"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40618-018-0898-9"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(17)30188-2"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15071724"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-44292-x"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2017.1371893"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2022.2047005"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12602-021-09839-8"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods12183383"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bonr.2018.02.001"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/lam.13525"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S169223"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2024.114820"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fbio.2024.104669"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2665-9913(19)30068-2"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41522-022-00348-2"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/fft2.449"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eng.2022.02.014"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2023.2197837"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2023.112704"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2023.113598"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15173829"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.877776"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2021.788576"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.748063"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2015.1010034"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2021.154767"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24065161"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-66653-2_8"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2023.2190304"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2020.109201"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-020-00591-6"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms11040950"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2021.104762"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-4262"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3635"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu10101513"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu12082340"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-017-0271-9"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00042-15"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.11.049"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.3945\/jn.116.243006"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v24.i23.2468"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.08.005"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aad0135"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22848"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard-2022-223626"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-023-01055-8"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.109017"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2018.10.013"},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.1210\/EN.2015-1308"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1080\/03008207.2017.1290085"},{"key":"e_1_3_4_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfutfo.2023.07.001"},{"key":"e_1_3_4_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2024.102196"},{"key":"e_1_3_4_65_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu12103161"},{"key":"e_1_3_4_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2023.106943"}],"container-title":["Gut Microbes Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/29933935.2026.2669712","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T10:23:21Z","timestamp":1778927001000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/29933935.2026.2669712"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,16]]},"references-count":65,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12,31]]}},"alternative-id":["10.1080\/29933935.2026.2669712"],"URL":"https:\/\/doi.org\/10.1080\/29933935.2026.2669712","relation":{},"ISSN":["2993-3935"],"issn-type":[{"value":"2993-3935","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,16]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kgmr20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kgmr20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-08-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-17","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2669712"}}