{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T08:31:32Z","timestamp":1789201892868,"version":"build-2803163510"},"reference-count":95,"publisher":"Informa UK Limited","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Neuropsychology"],"published-print":{"date-parts":[[2008,6,26]]},"DOI":"10.1080\/87565640802101482","type":"journal-article","created":{"date-parts":[[2008,6,21]],"date-time":"2008-06-21T03:28:43Z","timestamp":1214018923000},"page":"474-504","source":"Crossref","is-referenced-by-count":91,"title":["Twenty-Five Years of Research on Neurocognitive Outcomes in Early-Treated Phenylketonuria: Intelligence and Executive Function"],"prefix":"10.1080","volume":"33","author":[{"given":"Kathryn","family":"DeRoche","sequence":"first","affiliation":[{"name":"University of Northern Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilyn","family":"Welsh","sequence":"additional","affiliation":[{"name":"School of Psychological Sciences, University of Northern Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2008,6,20]]},"reference":[{"key":"e_1_3_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1986.tb10261.x"},{"key":"e_1_3_1_4_1","doi-asserted-by":"publisher","DOI":"10.1076\/chin.8.2.69.8725"},{"key":"e_1_3_1_5_1","doi-asserted-by":"publisher","DOI":"10.1076\/chin.8.4.231.13509"},{"key":"e_1_3_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2004.tb00477.x"},{"key":"e_1_3_1_7_1","first-page":"564","article-title":"Developmental timing of exposure to elevated levels of Phenylalanine","volume":"34","author":"*Antshel K. M.","year":"2003","unstructured":"*Antshel , K. M. and Waisbren , S. E. 2003a . Developmental timing of exposure to elevated levels of Phenylalanine . Journal of Abnormal Child Psychology , 34 : 564 \u2013 557 .","journal-title":"Journal of Abnormal Child Psychology"},{"key":"e_1_3_1_8_1","doi-asserted-by":"publisher","DOI":"10.1037\/0894-4105.17.3.458"},{"key":"e_1_3_1_9_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.121.1.65"},{"key":"e_1_3_1_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01957228"},{"key":"e_1_3_1_11_1","doi-asserted-by":"publisher","DOI":"10.1037\/0003-066X.57.2.111"},{"key":"e_1_3_1_12_1","volume-title":"Comprehensive meta-analysis Version 2: A computer program for research synthesis","author":"Borenstein M.","year":"2005","unstructured":"Borenstein , M. and Rothstein , H. 2005 . Comprehensive meta-analysis Version 2: A computer program for research synthesis , Englewood, New Jersey : Biostat. ."},{"key":"e_1_3_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(83)80007-9"},{"key":"e_1_3_1_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00014388"},{"key":"e_1_3_1_15_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199703000-00011"},{"key":"e_1_3_1_16_1","first-page":"223","article-title":"Monkey retarded learning analysis","volume":"22","author":"Chamove A. S.","year":"1978","unstructured":"Chamove , A. S. and Molinaro , T. J. 1978 . Monkey retarded learning analysis . Journal of Mental Deficiency Research , 22 : 223","journal-title":"Journal of Mental Deficiency Research"},{"key":"e_1_3_1_17_1","doi-asserted-by":"publisher","DOI":"10.1037\/0894-4105.18.4.613"},{"key":"e_1_3_1_18_1","doi-asserted-by":"publisher","DOI":"10.1037\/0894-4105.19.5.679"},{"key":"e_1_3_1_19_1","doi-asserted-by":"publisher","DOI":"10.1037\/0021-9010.89.5.780"},{"key":"e_1_3_1_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(84)90133-7"},{"key":"e_1_3_1_21_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj1810285"},{"key":"e_1_3_1_22_1","first-page":"255","article-title":"Neuropsychological studies on adolescents with phenylketonuria returned to phenylalanine-restricted diets","volume":"92","author":"Clarke J. T. R.","year":"1987","unstructured":"Clarke , J. T. R. , Gates , R. D. , Hogan , S. E. , Barrett , M. and MacDonald , G. W. 1987 . Neuropsychological studies on adolescents with phenylketonuria returned to phenylalanine-restricted diets . American Journal of Mental Retardation , 92 : 255 \u2013 262 .","journal-title":"American Journal of Mental Retardation"},{"key":"e_1_3_1_23_1","first-page":"155","article-title":"A power primer","volume":"112","author":"Cohen J.","year":"1992","unstructured":"Cohen , J. 1992 . A power primer . Quantitative Methods in Psychology , 112 : 155 \u2013 159 .","journal-title":"Quantitative Methods in Psychology"},{"key":"e_1_3_1_24_1","volume-title":"The handbook of research synthesis","author":"Cooper H.","year":"1994","unstructured":"Cooper , H. and Hegdes , L. 1994 . The handbook of research synthesis , New York : Russell Sage Foundation ."},{"key":"e_1_3_1_25_1","volume-title":"The biochemical basis of neurophramacology","author":"Cooper J. R.","year":"1991","unstructured":"Cooper , J. R. , Bloom , F. E. and Roth , R. H. 1991 . The biochemical basis of neurophramacology , 6th , New York : Oxford University Press .","edition":"6"},{"key":"e_1_3_1_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(72)90406-8"},{"key":"e_1_3_1_27_1","volume-title":"Meta-analysis of intelligence and executive function outcomes in early-treated phenylketonuria","author":"DeRoche K.","year":"2005","unstructured":"DeRoche , K. 2005 . Meta-analysis of intelligence and executive function outcomes in early-treated phenylketonuria , Greeley, Colorado, , USA : University of Northern Colorado . Unpublished master's thesis"},{"key":"e_1_3_1_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02126298"},{"key":"e_1_3_1_29_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.14-05-03072.1994"},{"key":"e_1_3_1_30_1","doi-asserted-by":"publisher","DOI":"10.2307\/1166208"},{"key":"e_1_3_1_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2779(1999)5:2<104::AID-MRDD2>3.0.CO;2-7"},{"key":"e_1_3_1_32_1","first-page":"367","volume-title":"Attention, memory, and executive function","author":"Eslinger P. J.","year":"1996","unstructured":"Eslinger , P. J. 1996 . \u201c Conceptualizing, describing, and measuring components of executive function: A summary \u201d . In Attention, memory, and executive function , Edited by: Lyon , G. R. and Krasnagor , N. A. 367 \u2013 395 . Baltimore : Paul H. Brookes. ."},{"key":"e_1_3_1_33_1","first-page":"113","volume-title":"Developmental variations in learning: Applications to social, executive function, language, and reading skills","author":"Espy K. A.","year":"2002","unstructured":"Espy , K. A. and Kaufmann , P. M. 2002 . \u201c Individual differences in the development of executive function in children: Lessons from the delayed response and A-not-B tasks \u201d . In Developmental variations in learning: Applications to social, executive function, language, and reading skills , Edited by: Molfese , D. L. and Molfese , V. J. 113 \u2013 137 . Mahwah, NJ : Erlbaum. ."},{"key":"e_1_3_1_34_1","first-page":"106","article-title":"Personality characteristics of nonretarded pheylkenturics and their family members","volume":"42","author":"Fish R. O.","year":"1981","unstructured":"Fish , R. O. , Sines , L. K. and Chang , P. 1981 . Personality characteristics of nonretarded pheylkenturics and their family members . Journal of Clinical Psychiatry , 42 : 106 \u2013 113 .","journal-title":"Journal of Clinical Psychiatry"},{"key":"e_1_3_1_35_1","volume-title":"The developmental psychology of planning: Why, how and when do we plan?","author":"Friedman S. L.","year":"1997","unstructured":"Friedman , S. L. and Scholnick , E. L. 1997 . The developmental psychology of planning: Why, how and when do we plan? , Hillsdale, NJ : Lawrence Erlbaum Associates ."},{"key":"e_1_3_1_36_1","doi-asserted-by":"publisher","DOI":"10.1348\/000709900158047"},{"key":"e_1_3_1_37_1","doi-asserted-by":"publisher","DOI":"10.1080\/01688639408402650"},{"key":"e_1_3_1_38_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1005339524847"},{"key":"e_1_3_1_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2788.1995.tb00540.x"},{"key":"e_1_3_1_40_1","doi-asserted-by":"publisher","DOI":"10.53841\/bpsecp.2005.22.2.81"},{"key":"e_1_3_1_41_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.82.3.209"},{"key":"e_1_3_1_42_1","doi-asserted-by":"publisher","DOI":"10.1086\/301920"},{"key":"e_1_3_1_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01799701"},{"key":"e_1_3_1_44_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199607000-00004"},{"key":"e_1_3_1_45_1","doi-asserted-by":"publisher","DOI":"10.1037\/1082-989X.9.4.426"},{"key":"e_1_3_1_46_1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/1475-3588.00024","article-title":"Measuring executive functions in childhood: Problems and solutions?","volume":"7","author":"Hughes C.","year":"2002","unstructured":"Hughes , C. and Graham , A. 2002 . Measuring executive functions in childhood: Problems and solutions? . Child and Adolescent Mental Health , 7 : 131 \u2013 142 .","journal-title":"Child and Adolescent Mental Health"},{"key":"e_1_3_1_47_1","doi-asserted-by":"publisher","DOI":"10.1207\/S15326942DN2202_4"},{"key":"e_1_3_1_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-7634(02)00040-4"},{"key":"e_1_3_1_49_1","volume-title":"Methods of meta-analysis","author":"Hunter J. E.","year":"1990","unstructured":"Hunter , J. E. and Schmidt , F. L. 1990 . Methods of meta-analysis , Newbury Park, CA : Sage Publications ."},{"key":"e_1_3_1_50_1","doi-asserted-by":"publisher","DOI":"10.1086\/301638"},{"key":"e_1_3_1_51_1","first-page":"266","volume-title":"The metabolic basis of inherited disease","author":"Knox W. E.","year":"1972","unstructured":"Knox , W. E. 1972 . \u201c Phenylketonuria \u201d . In The metabolic basis of inherited disease , Edited by: Stanbury , J. B. , Wyngaarden , J. B. and Fredrickson , D. S. 266 \u2013 295 . New York : McGraw-Hill. ."},{"key":"e_1_3_1_52_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-198611000-00010"},{"key":"e_1_3_1_53_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI111695"},{"key":"e_1_3_1_54_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-0663.92.3.449"},{"key":"e_1_3_1_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01800008"},{"key":"e_1_3_1_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/1467-8624.00370"},{"key":"e_1_3_1_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(72)90653-1"},{"key":"e_1_3_1_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02126297"},{"key":"e_1_3_1_59_1","first-page":"111","article-title":"An analysis of visual motor problems in children with dietary treated phenylketonuria","volume":"3","author":"*Mims S. S.","year":"1983","unstructured":"*Mims , S. S. , McIntyre , C. W. and Murray , M. E. 1983 . An analysis of visual motor problems in children with dietary treated phenylketonuria . Educational and Psychological Research , 3 : 111 \u2013 121 .","journal-title":"Educational and Psychological Research"},{"key":"e_1_3_1_60_1","first-page":"327","volume-title":"Attention, memory and executive function","author":"Pennington B. F.","year":"1995","unstructured":"Pennington , B. F. , Bennetto , L. , McAleer , O. K. and Roberts , R. J. Jr. 1995 . \u201c Executive functions and working memory: Theoretical and measurement issues \u201d . In Attention, memory and executive function , Edited by: Lyon , G. R. and Krasnegor , N. A. 327 \u2013 348 . Baltimore, Maryland : Paul H. Brookes Publishing Company. ."},{"key":"e_1_3_1_61_1","first-page":"467","article-title":"Neuropsychological deficits in early treated phenylketonuric children","volume":"89","author":"Pennington B. F.","year":"1985","unstructured":"Pennington , B. F. , van Doorninck , W. J. , McCabe , L. L. and McCabe , E. R. 1985 . Neuropsychological deficits in early treated phenylketonuric children . American Journal of Mental Deficiency , 89 : 467 \u2013 474 .","journal-title":"American Journal of Mental Deficiency"},{"key":"e_1_3_1_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004310050945"},{"key":"e_1_3_1_63_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.201.2.8888233"},{"key":"e_1_3_1_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00014255"},{"key":"e_1_3_1_65_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1005389110739"},{"key":"e_1_3_1_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(94)70360-4"},{"key":"e_1_3_1_67_1","first-page":"1667","volume-title":"The metabolic and molecular basis of inherited disease","author":"Scriver C. R.","year":"2001","unstructured":"Scriver , C. R. and Kaufman , S. 2001 . \u201c Hyperphenylalaninemia: Phenylalanine hydroxylase definciency \u201d . In The metabolic and molecular basis of inherited disease , 8th , Edited by: Scriver , C. R. , Beaudet , A. L. , Sly , W. S. and Valle , D. 1667 \u2013 1724 . New York : McGraw Hill. .","edition":"8"},{"key":"e_1_3_1_68_1","volume-title":"From neurons to neighborhoods: The science of early childhood development","author":"Shonkoff J. P.","year":"2000","unstructured":"Shonkoff , J. P. and Phillips , D. A. 2000 . From neurons to neighborhoods: The science of early childhood development , Washington, DC : National Academy Press ."},{"key":"e_1_3_1_69_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.16.12.1572"},{"key":"e_1_3_1_70_1","volume-title":"The metabolic basis of inherited disease","author":"Stanbury J. B.","year":"1983","unstructured":"Stanbury , J. B. , Wyndgaarden , J. B. and Friedrickson , D. S. 1983 . The metabolic basis of inherited disease , 2nd , New York : McGraw-Hill .","edition":"2"},{"key":"e_1_3_1_71_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1005669610722"},{"key":"e_1_3_1_72_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02276719"},{"key":"e_1_3_1_73_1","doi-asserted-by":"publisher","DOI":"10.1207\/S15326942DN160103"},{"key":"e_1_3_1_74_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.95.1.3"},{"key":"e_1_3_1_75_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1994.tb13459.x"},{"key":"e_1_3_1_76_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00711827"},{"key":"e_1_3_1_77_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00014256"},{"key":"e_1_3_1_78_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.81.3.299"},{"key":"e_1_3_1_79_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.85.12.1636"},{"key":"e_1_3_1_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1994.tb13464.x"},{"key":"e_1_3_1_81_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02312549"},{"key":"e_1_3_1_82_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.79.3.351"},{"key":"e_1_3_1_83_1","first-page":"411","article-title":"Neurological findings in early treated phenylketonuria","volume":"84","author":"*Weglage J.","year":"1995","unstructured":"*Weglage , J. , Pietsch , M. , Funders , B. , Koch , H. G. and Ullrich , K. 1995 . Neurological findings in early treated phenylketonuria . Acta Paediatrica , 84 : 411 \u2013 415 .","journal-title":"Acta Paediatrica"},{"key":"e_1_3_1_84_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01953938"},{"key":"e_1_3_1_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00014259"},{"key":"e_1_3_1_86_1","first-page":"767","volume-title":"Handbook of brain and behaviour development","author":"Welsh M. C.","year":"2001","unstructured":"Welsh , M. C. 2001 . \u201c The prefrontal cortex and the development of executive functions \u201d . In Handbook of brain and behaviour development , Edited by: Kalverboer , A. and Gramsbergen , A. 767 \u2013 789 . The Netherlands : Kluwer. ."},{"key":"e_1_3_1_87_1","first-page":"139","volume-title":"Developmental variations in language and learning","author":"Welsh M. C.","year":"2002","unstructured":"Welsh , M. C. 2002 . \u201c Developmental and clinical variations in executive functions \u201d . In Developmental variations in language and learning , Edited by: Kirk , U. and Molfese , D. 139 \u2013 185 . Hillsdale, New Jersey : Erlbaum. ."},{"key":"e_1_3_1_88_1","volume-title":"Developmental cognitive neuroscience handbook","author":"Welsh M.","unstructured":"Welsh , M. , DeRoche , K. and Gilliam , D. \u201c Early-treated Phenylketonuria: Neurocognitive models of early-treated Phenylketonuria: Insights from meta-analysis and new molecular genetic findings \u201d . In Developmental cognitive neuroscience handbook , Edited by: Nelson , C. A. and Luciana , M. Cambridge, MA : The MIT Press. . in press"},{"key":"e_1_3_1_89_1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1002\/9780470757703.ch9","volume-title":"Blackwell handbook of early childhood development","author":"Welsh M. C.","year":"2006","unstructured":"Welsh , M. C. , Friedman , S. L. and Spieker , S. J. 2006 . \u201c Executive functions in developing children: Current conceptualizations and questions for the future \u201d . In Blackwell handbook of early childhood development , Edited by: McCartney , K. and Phillips , D. 167 \u2013 187 . Malden, MA : Blackwell Publishing. ."},{"key":"e_1_3_1_90_1","volume-title":"Treatment regimens and their effectiveness: A meta-analytic review","author":"Welsh M.","year":"2000","unstructured":"Welsh , M. , Kelley , G. and Tran , Z. V. 2000 . Treatment regimens and their effectiveness: A meta-analytic review , Technical Report prepared for the NIH Consensus Development Conference on Early-Treated Phenylketonuria ."},{"key":"e_1_3_1_91_1","first-page":"275","volume-title":"Pediatric neuropsychology","author":"Welsh M.","year":"2000","unstructured":"Welsh , M. and Pennington , B. 2000 . \u201c Phenylketonuria \u201d . In Pediatric neuropsychology , 1st , Edited by: Yeates , K. O. , Ris , M. D. and Taylor , H. G. 275 \u2013 299 . New York : The Guilford Press. .","edition":"1"},{"key":"e_1_3_1_92_1","doi-asserted-by":"publisher","DOI":"10.2307\/1130832"},{"key":"e_1_3_1_93_1","doi-asserted-by":"publisher","DOI":"10.1037\/0894-4105.15.2.221"},{"key":"e_1_3_1_94_1","doi-asserted-by":"publisher","DOI":"10.1017\/S135561770102001X"},{"key":"e_1_3_1_95_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.60.6.815"},{"key":"e_1_3_1_96_1","doi-asserted-by":"publisher","DOI":"10.1111\/1467-8721.ep10774761"},{"key":"e_1_3_1_97_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0037-976X.2003.00261.x"}],"container-title":["Developmental Neuropsychology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/87565640802101482","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T12:42:28Z","timestamp":1744202548000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/87565640802101482"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6,20]]},"references-count":95,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,6,26]]}},"alternative-id":["10.1080\/87565640802101482"],"URL":"https:\/\/doi.org\/10.1080\/87565640802101482","relation":{},"ISSN":["8756-5641","1532-6942"],"issn-type":[{"value":"8756-5641","type":"print"},{"value":"1532-6942","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,6,20]]}}}