{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T10:40:11Z","timestamp":1767868811148,"version":"3.49.0"},"reference-count":19,"publisher":"Informa UK Limited","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecological Endocrinology"],"published-print":{"date-parts":[[2003,1]]},"DOI":"10.1080\/gye.17.3.207.214","type":"journal-article","created":{"date-parts":[[2009,12,7]],"date-time":"2009-12-07T12:01:27Z","timestamp":1260187287000},"page":"207-214","source":"Crossref","is-referenced-by-count":67,"title":["The effect of metformin on ovarian stimulation and<i>in vitro<\/i>fertilization in insulin-resistant women with polycystic ovary syndrome: an open-label randomized cross-over trial"],"prefix":"10.1080","volume":"17","author":[{"given":"P.","family":"Fedorcs\u00e1k","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. O.","family":"Dale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Storeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"\u00c5byholm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Tanbo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,8,28]]},"reference":[{"key":"CIT0001","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S0889-8529(05)70078-5","volume":"28","author":"Ehrrnann DA","year":"1999","journal-title":"Endocrinol Metab Clin North Am"},{"key":"CIT0003","first-page":"310","volume":"75","author":"Vandermolen DT","year":"2001","journal-title":"Metformin increases the ovulatory rate and pregnancy rate from clomiphene citrate in patients with polycystic ovary syndrome who are resistant to clomiphene citrate alone. Fertil Steril"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/S0015-0282(99)00208-3","volume":"72","author":"De Leo V","year":"1999","journal-title":"Fertil Steril"},{"key":"CIT0005","first-page":"1097","volume":"73","author":"Kim LH","year":"2000","journal-title":"Barbieri RL. Insulin sensitizers and polycystic ovary syndrome: can a diabetes medi-cation treat infertility? Fertil Steril"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1067\/mob.2000.107627","volume":"183","author":"Barbieri RL","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"CIT0007","first-page":"203","volume":"900","author":"Diamanti-Kandarakis E","year":"2000","journal-title":"Insulin sensitizers and antiandrogens in the treatment o fp olycystic ovary syndrome. Ann N Y Acad Sci"},{"key":"CIT0008","first-page":"1194","volume":"8","author":"Duleba AJ","year":"1993","journal-title":"Insulin actions on ovarian steroidogenesis are not modulated by metformin. Hum Reprod"},{"key":"CIT0010","first-page":"517","volume":"76","author":"Attia GR","year":"2001","journal-title":"Metformin directly inhibits androgen production in human thecal cells. Fertil Steril"},{"key":"CIT0011","first-page":"1086","volume":"16","author":"Fedorcsik P","year":"2001","journal-title":"The impact of obesity and insulin resistance on the outcome of IVF or ICSI in women with polycystic ovarian syndrome. Hum Reprod"},{"key":"CIT0012","first-page":"505","volume":"75","author":"Stadtmauer LA","year":"2001","journal-title":"Metformin treatment of patients with polycystic ovary syndrome undergoing in vitro fertilization improves outcomes and is associated with modulation of the insulin-like growth factors. Fertil Steril"},{"key":"CIT0013","first-page":"1375","volume":"2","author":"Adams J","year":"1985","journal-title":"Polson DW. Multifollicular ovaries: clinical and endocrine features and response to pulsatile gonadotropin releasing hormone. Lancet"},{"key":"CIT0014","first-page":"401","volume":"28","author":"HoskerJP, Matthews DR,","year":"1985","journal-title":"Rudenski AS. Continuous infusion of glucose with model assessment: measure-ments of insulin resistance and beta-cell function in man. Diabetologia"},{"key":"CIT0015","first-page":"567","volume":"13","author":"Dale PO","year":"1998","journal-title":"The impact of insulin resistance on the outcome of ovulation induction with low-dose follicle stimulating hormone in women with polycystic ovary syndrome. Hum Rep rod"},{"key":"CIT0016","author":"Berry DA","year":"1996","journal-title":"Statistics: A Bayesian Perspective. Belmont"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1210\/jcem.84.4.5727","volume":"84","author":"Yuan W","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0889-8529(05)70074-8","volume":"28","author":"Franks S","year":"1999","journal-title":"Endocrinol Metab Clin North Am"},{"key":"CIT0021","first-page":"939","volume":"65","author":"Khan KS","year":"1996","journal-title":"Collins JA. Empirical evidence of bias in infertility research: overestimation of treat-ment effect in crossover trials using pregnancy as the outcome measure. Fertil Steril"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S0015-0282(98)00114-9","volume":"70","author":"Cohlen BJ","year":"1998","journal-title":"Fertil Steril"},{"key":"CIT0023","first-page":"1621","volume":"311","author":"Lilford RJ","year":"1995","journal-title":"Braunholtz D. Clinical trials and rare diseases: a way out of a conundrum. Br MedJ"}],"container-title":["Gynecological Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/gye.17.3.207.214","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,18]],"date-time":"2017-06-18T22:28:02Z","timestamp":1497824882000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1080\/gye.17.3.207.214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1]]},"references-count":19,"aliases":["10.1080\/713603249","10.1080\/713603249"],"journal-issue":{"issue":"3","published-online":{"date-parts":[[2009,8,28]]},"published-print":{"date-parts":[[2003,1]]}},"alternative-id":["10.1080\/gye.17.3.207.214"],"URL":"https:\/\/doi.org\/10.1080\/gye.17.3.207.214","relation":{},"ISSN":["0951-3590","1473-0766"],"issn-type":[{"value":"0951-3590","type":"print"},{"value":"1473-0766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,1]]}}}