{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T07:54:52Z","timestamp":1770969292126,"version":"3.50.1"},"reference-count":42,"publisher":"Informa UK Limited","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Xenobiotica"],"published-print":{"date-parts":[[2006,8,1]]},"DOI":"10.1080\/00498250600790331","type":"journal-article","created":{"date-parts":[[2006,8,4]],"date-time":"2006-08-04T22:07:23Z","timestamp":1154729243000},"page":"724-737","source":"Crossref","is-referenced-by-count":25,"title":["Kinetics of paraquat in the isolated rat lung: Influence of sodium depletion"],"prefix":"10.1080","volume":"36","author":[{"given":"R. J.","family":"Dinis-Oliveira","sequence":"first","affiliation":[]},{"given":"M. J. De Jes\u00fas","family":"Valle","sequence":"additional","affiliation":[]},{"given":"M. L.","family":"Bastos","sequence":"additional","affiliation":[]},{"given":"F.","family":"Carvalho","sequence":"additional","affiliation":[]},{"given":"A.","family":"S\u00e1nchez Navarro","sequence":"additional","affiliation":[]}],"member":"301","reference":[{"key":"E00001","unstructured":"Aziz, SM and Lipke, DW and Olson, JW and Gillespie, MN. (1994) Role of ATP and sodium in polyamine transport in bovine pulmonary artery smooth cells <i>Biochemistry and Pharmacology<\/i>, 48, pp. 1611 - 1618."},{"key":"E00002","unstructured":"Blaszczynski, M and Litwinska, J and Zaborowska, D and Bilinski, T. (1985) The role of respiratory chain in paraquat toxicity in yeast <i>Acta Microbiologica Polonica<\/i>, 34, pp. 243 - 254."},{"key":"E00003","doi-asserted-by":"crossref","unstructured":"Burk, RF and Lawrence, RA and Lane, JM. (1980) Liver necrosis and lipid peroxidation in the rat as a result of paraquat and diquat administration. Effect of selenium deficiency <i>Journal of Clinical Investigation<\/i>, 65, pp. 1024 - 1031.","DOI":"10.1172\/JCI109754"},{"key":"E00004","unstructured":"Bus, JS and Aust, SD and Gibson, JE. (1974) Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity <i>Biochemical and Biophysical Research Communications<\/i>, 58, pp. 749 - 755."},{"key":"E00005","unstructured":"Bus, JS and Aust, SD and Gibson, JE. (1975) Lipid peroxidation: A possible mechanism for paraquat toxicity <i>Research Communications in Chemistry, Pathology and Pharmacology<\/i>, 11, pp. 31 - 38."},{"key":"E00006","unstructured":"Clejan, L and Cederbaum, AI. (1989) Synergistic interaction between NADPH-cytochrome P-450 reductase, paraquat and iron in the generation of active oxygen radicals <i>Biochemistry and Pharmacology<\/i>, 38, pp. 1779 - 1786."},{"key":"E00007","unstructured":"Dicker, E and Cederbaum, AI. (1991) NADH-dependent generation of reactive oxygen species by microsomes in the presence of iron and redox cycling agents <i>Biochemistry and Pharmacology<\/i>, 42, pp. 529 - 535."},{"key":"E00008","unstructured":"Dinsdale, D and Preston, SG and Nemery, B. (1991) Effects of injury on [3H]putrescine uptake by types I and II cells in rat lung slices <i>Experimental Molecular Pathology<\/i>, 54, pp. 218 - 229."},{"key":"E00009","unstructured":"Fell, AF and Jarvie, DR and Stewart, MJ. (1981) Analysis for paraquat by second- and fourth-derivative spectroscopy <i>Clinical Chemistry<\/i>, 27, pp. 286 - 292."},{"key":"E00010","unstructured":"Fuke, C and Ameno, K and Ameno, S and Kiriu, T and Shinohara, T and Sogo, K and Ijiri, I. (1992) A rapid, simultaneous determination of paraquat and diquat in serum and urine using second-derivative spectroscopy <i>Journal of Analytical Toxicology<\/i>, 16, pp. 214 - 216."},{"key":"E00011","doi-asserted-by":"crossref","unstructured":"Fukushima, T and Yamada, K and Hojo, N and Isobe, A and Shiwaku, K and Yamane, Y. (1994) Mechanism of cytotoxicity of paraquat. III. The effects of acute paraquat exposure on the electron transport system in rat mitochondria <i>Experiments in Toxicology and Pathology<\/i>, 46, pp. 437 - 441.","DOI":"10.1016\/S0940-2993(11)80056-4"},{"key":"E00012","doi-asserted-by":"crossref","unstructured":"Fukushima, T and Yamada, K and Isobe, A and Shiwaku, K and Yamane, Y. (1993) Mechanism of cytotoxicity of paraquat. I. NADH oxidation and paraquat radical formation via complex I <i>Experiments in Toxicology and Pathology<\/i>, 45, pp. 345 - 349.","DOI":"10.1016\/S0940-2993(11)80424-0"},{"key":"E00013","unstructured":"Gordonsmith, RH and Brooke-Taylor, S and Smith, LL and Cohen, GM. (1983) Structural requirements of compounds to inhibit pulmonary diamine accumulation <i>Biochemistry and Pharmacology<\/i>, 32, pp. 3701 - 3709."},{"key":"E00014","unstructured":"Hirai, K and Witschi, H and Cote, MG. (1985) Mitochondrial injury of pulmonary alveolar epithelial cells in acute paraquat intoxication <i>Experimental Molecular Pathology<\/i>, 43, pp. 242 - 252."},{"key":"E00015","unstructured":"Janne, J and Poso, H and Raina, A. (1978) Polyamines in rapid growth and cancer <i>Biochimica et Biophysica Acta<\/i>, 473, pp. 241 - 293."},{"key":"E00016","doi-asserted-by":"crossref","unstructured":"Kumagai, J and Johnson, LR. (1988) Characteristics of putrescine uptake in isolated rat enterocytes <i>American Journal of Physiology<\/i>, 254, pp. G81 - G6.","DOI":"10.1152\/ajpgi.1988.254.1.G81"},{"key":"E00017","unstructured":"Kuo, TL and Lin, DL and Liu, RH and Moriya, F and Hashimoto, Y. (2001) Spectra interference between diquat and paraquat by second derivative spectrophotometry <i>Forensic Science International<\/i>, 121, pp. 134 - 139."},{"key":"E00018","unstructured":"LaVoie, MJ and Hastings, TG. (1999) Peroxynitrite- and nitrite-induced oxidation of dopamine: Implications for nitric oxide in dopaminergic cell loss <i>Journal of Neurochemistry<\/i>, 73, pp. 2546 - 2554."},{"key":"E00019","unstructured":"Lewis, CP and Haschek, WM and Wyatt, I and Cohen, GM and Smith, LL. (1989) The accumulation of cystamine and its metabolism to taurine in rat lung slices <i>Biochemical Pharmacology<\/i>, 38, pp. 481 - 488."},{"key":"E00020","unstructured":"Lowry, OHN and Rosebrough, NJ and Farr, AL and Randall, RJ. (1951) Protein measurement with Folin phenol reagent <i>Journal of Biology and Chemistry<\/i>, 193, pp. 265 - 275."},{"key":"E00021","unstructured":"Martinez, MSM and Gandarillas, CIC and Lanao, JM and Sanchez Navarro, A. (2005) Influence of flow rate on the disposition of levofloxacin and netilmicin in the isolated rat lung <i>European Journal of Pharmaceutical Science<\/i>, 24, pp. 325 - 332."},{"key":"E00022","unstructured":"Morgan, DM. (1992) Uptake of polyamines by human endothelial cells. Characterization and lack of effect of agonists of endothelial function <i>Biochemical Journal<\/i>, 286, pp. 413 - 417."},{"key":"E00023","unstructured":"Nemery, B and Smith, LL and Aldridge, WN. (1987) Putrescine and 5-hydroxytryptamine accumulation in rat lung slices: Cellular localization and responses to cell-specific lung injury <i>Toxicology and Applied Pharmacology<\/i>, 91, pp. 107 - 120."},{"key":"E00024","unstructured":"Onyeama, HP and Oehme, FW. (1984) A literature review of paraquat toxicity <i>Veterinary and Human Toxicology<\/i>, 26, pp. 494 - 502."},{"key":"E00025","unstructured":"Rannels, DE and Kameji, R and Pegg, AE and Rannels, SR. (1989) Spermidine uptake by type II pneumocytes: Interactions of amine uptake pathways <i>American Journal of Physiology, Lung Cell and Molecular Physiology<\/i>, 257, pp. L346 - L353."},{"key":"E00026","unstructured":"Rannels, DE and Pegg, AE and Clark, RS and Addison, JL. (1985) Interaction of paraquat and amine uptake by rat lungs perfused in situ <i>American Journal of Physiology, Endocrinology and Metabolism<\/i>, 249, pp. E506 - E513."},{"key":"E00027","unstructured":"Rinehart, CAJ and Chen, KY. (1984) Characterization of the polyamine transport system in mouse neuroblastoma cells. Effects of sodium and system A amino acids <i>Journal of Biology and Chemistry<\/i>, 259, pp. 4750 - 4756."},{"key":"E00028","unstructured":"Rose, MS and Smith, LL and Wyatt, I. (1974) Evidence for energy-dependent accumulation of paraquat into rat lung <i>Nature<\/i>, 252, pp. 314 - 315."},{"key":"E00029","unstructured":"Ross, JH and Krieger, RI. (1981) Structure\u2013activity correlations of amines inhibiting active uptake of paraquat (methyl viologen) into rat lung slices <i>Toxicology and Applied Pharmacology<\/i>, 59, pp. 238 - 249."},{"key":"E00030","unstructured":"Smith, LL. (1982) The identification of an accumulation system for diamines and polyamines into the lung and its relevance to paraquat toxicity <i>Archives in Toxicology Suppl<\/i>, 5, pp. 1 - 14."},{"key":"E00031","unstructured":"Smith, LL and Wyatt, I. (1981) The accumulation of putrescine into slices of rat lung and brain and its relationship to the accumulation of paraquat <i>Biochemistry and Pharmacology<\/i>, 30, pp. 1053 - 1058."},{"key":"E00032","unstructured":"Sorokin, SP.(1970) The cells of the lungs. In <i>Morphology of experimental respiratory carcinogenesis<\/i>. . Washington DC: US Atomic Energy Commission."},{"key":"E00033","unstructured":"Tawara, T and Fukushima, T and Hojo, N and Isobe, A and Shiwaku, K and Setogawa, T and Yamane, Y. (1996) Effects of paraquat on mitochondrial electron transport system and catecholamine contents in rat brain <i>Archives in Toxicology<\/i>, 70, pp. 585 - 589."},{"key":"E00034","unstructured":"Thakar, JH and Hassan, MN. (1988) Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), cyperquat (MPP+) and paraquat on isolated mitochondria from rat striatum, cortex and liver <i>Life Sciences<\/i>, 43, pp. 143 - 149."},{"key":"E00035","unstructured":"Tomita, M. (1991) Comparison of one-electron reduction activity against the bipyridylium herbicides, paraquat and diquat, in microsomal and mitochondrial fractions of liver, lung and kidney (in vitro) <i>Biochemistry and Pharmacology<\/i>, 42, pp. 303 - 309."},{"key":"E00036","unstructured":"Weiss, M.(1995) Distribution kinetics in the body and single organs: Moment analysis. In <i>Advanced methods of pharmacokinetics and pharmacodynamic system analysis<\/i>. ( pp. 89 - 100 ). New York NY: Plenum."},{"key":"E00037","unstructured":"Weiss, M and Roberts, MS. (1996) Tissue distribution kinetics as determinant of transit time dispersion of drugs in organs: Application of a stochastic model to the rat hindlimb <i>Journal of Pharmacokinetics and Biopharmacology<\/i>, 24, pp. 173 - 196."},{"key":"E00038","unstructured":"Wesseling, C and Hogstedt, C and Picado, A and Johansson, L. (1997) Unintentional fatal paraquat poisonings among agricultural workers in Costa Rica: Report of 15 cases <i>American Journal of Industrial Medicine<\/i>, 32, pp. 433 - 441."},{"key":"E00039","unstructured":"Wesseling, C and van Wendel de Joode, B and Ruepert, C and Leon, C and Monge, P and Hermosillo, H and Partanen, TJ. (2001) Paraquat in developing countries <i>International Journal of Occupational and Environmental Health<\/i>, 7, pp. 275 - 286."},{"key":"E00040","doi-asserted-by":"crossref","unstructured":"Yamada, K and Fukushima, T. (1993) Mechanism of cytotoxicity of paraquat. II. Organ specificity of paraquat-stimulated lipid peroxidation in the inner membrane of mitochondria <i>Experiments in Toxicology and Pathology<\/i>, 45, pp. 375 - 380.","DOI":"10.1016\/S0940-2993(11)80433-1"},{"key":"E00041","unstructured":"Yamaoka, K and Nakagawa, T and Uno, T. (1978) Statistical moments in pharmacokinetics <i>Journal of Pharmacokinetics and Biopharmacology<\/i>, 6, pp. 547 - 558."},{"key":"E00042","unstructured":"Youngman, RJ and Elstner, EF. (1981) Oxygen species in paraquat toxicity: The crypto-OH radical <i>FEBS Letters<\/i>, 129, pp. 265 - 268."}],"container-title":["Xenobiotica"],"original-title":[],"deposited":{"date-parts":[[2019,4,20]],"date-time":"2019-04-20T10:27:48Z","timestamp":1555756068000},"score":1,"resource":{"primary":{"URL":"http:\/\/taylorandfrancis.metapress.com\/Index\/10.1080\/00498250600790331"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8,1]]},"references-count":42,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2006,8,1]]}},"alternative-id":["Q07V84RL581561H7"],"URL":"https:\/\/doi.org\/10.1080\/00498250600790331","relation":{},"ISSN":["0049-8254","1366-5928"],"issn-type":[{"value":"0049-8254","type":"print"},{"value":"1366-5928","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,8,1]]}}}