{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T17:30:15Z","timestamp":1762018215367,"version":"3.37.3"},"reference-count":82,"publisher":"Informa UK Limited","issue":"1","funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"CNPq (Conselho Nacional de DesenvolvimentoCient\u00edfico e Tecnol\u00f3gico\/National Counsel of Technological and Scientific Development of Brazi","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004809","name":"FINEP (Financiadora de Estudos e Projetos\/Financier of Studies and Projects of Brazil","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002924","name":"FEDER - Fundo Europeu de Desenvolvimento Regional funds","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002924","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006129","name":"- Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia\/Minist\u00e9rio da Ci\u00eancia, Tecnologia e Inova\u00e7\u00e3o","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006129","name":"\u00a0FCT\u00a0","doi-asserted-by":"publisher","award":["PEst-C\/EQB\/LA0006\/2013","NORTE-07\u20130124-FEDER-000069]","UID\/QUI\/50006","NORTE-07\u20130124-FEDER-000069"],"award-info":[{"award-number":["PEst-C\/EQB\/LA0006\/2013","NORTE-07\u20130124-FEDER-000069]","UID\/QUI\/50006","NORTE-07\u20130124-FEDER-000069"]}],"id":[{"id":"10.13039\/100006129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002924","name":"European Union","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002924","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Funds"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Pharmaceutical Development and Technology"],"published-print":{"date-parts":[[2020,1,2]]},"DOI":"10.1080\/10837450.2019.1669643","type":"journal-article","created":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T14:13:27Z","timestamp":1568902407000},"page":"54-67","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":15,"title":["Design and characterization of an organogel system containing ascorbic acid microparticles produced with propolis by-product"],"prefix":"10.1080","volume":"25","author":[{"given":"Lizziane Maria Belloto","family":"de Francisco","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Laboratory of Research and Development of Drug Delivery Systems, Postgraduate Program in Pharmaceutical Sciences, State University of Maringa, Maringa, Brazil;"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8534-3739","authenticated-orcid":false,"given":"Diana","family":"Pinto","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, Faculty of Pharmacy, REQUIMTE\/LAQV, University of Porto, Porto, Portugal;"},{"name":"REQUIMTE\/LAQV, Instituto Superior de Engenharia do Porto, Porto, Portugal;"}]},{"given":"H\u00e9len C\u00e1ssia","family":"Rosseto","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Laboratory of Research and Development of Drug Delivery Systems, Postgraduate Program in Pharmaceutical Sciences, State University of Maringa, Maringa, Brazil;"}]},{"given":"Lucas de Alc\u00e2ntara Sica","family":"de Toledo","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Laboratory of Research and Development of Drug Delivery Systems, Postgraduate Program in Pharmaceutical Sciences, State University of Maringa, Maringa, Brazil;"}]},{"given":"Rafaela Said","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Laboratory of Research and Development of Drug Delivery Systems, Postgraduate Program in Pharmaceutical Sciences, State University of Maringa, Maringa, Brazil;"}]},{"given":"Paulo Jorge Cardoso da","family":"Costa","sequence":"additional","affiliation":[{"name":"REQUIMTE\/UCIBIO, MedTech-Laboratory of Pharmaceutical Technology, Department of Drug Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal;"}]},{"given":"M. Beatriz P. P.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, Faculty of Pharmacy, REQUIMTE\/LAQV, University of Porto, Porto, Portugal;"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5763-7553","authenticated-orcid":false,"given":"Bruno","family":"Sarmento","sequence":"additional","affiliation":[{"name":"i3S \u2013 Instituto de Investiga\u00e7\u00e3o e Inova\u00e7\u00e3o em Sa\u00fade, University of Porto, Porto, Portugal;"},{"name":"iNEB \u2013 Instituto de Engenharia Biom\u00e9dica, University of Porto, Porto, Portugal;"},{"name":"CESPU, Instituto de Investiga\u00e7\u00e3o e Forma\u00e7\u00e3o Avan\u00e7ada em Ci\u00eancias e Tecnologias da Sa\u00fade &amp; Instituto Universit\u00e1rio de Ci\u00eancias da Sa\u00fade, Gandra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8803-0041","authenticated-orcid":false,"given":"Francisca","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, Faculty of Pharmacy, REQUIMTE\/LAQV, University of Porto, Porto, Portugal;"},{"name":"REQUIMTE\/LAQV, Instituto Superior de Engenharia do Porto, Porto, Portugal;"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4838-5742","authenticated-orcid":false,"given":"Marcos Luciano","family":"Bruschi","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Laboratory of Research and Development of Drug Delivery Systems, Postgraduate Program in Pharmaceutical Sciences, State University of Maringa, Maringa, Brazil;"}]}],"member":"301","published-online":{"date-parts":[[2019,10,3]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2010.01.052"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.18433\/J3HW2B"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2013.10.001"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2006.07.036"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2008.02.001"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2007.07.017"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf1031229"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2008.09.028"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2011.03.054"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.indcrop.2014.12.049"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/10837450.2010.508074"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2007.09.030"},{"issue":"4","key":"e_1_3_2_14_1","first-page":"224","article-title":"Intracoronary poloxamer 188 Prevents reperfusion injury in a porcine model of st-segment elevation myocardial infarction","volume":"1","author":"Bartos JA","year":"2016","unstructured":"Bartos JA, Matsuura TR, Tsangaris A, Olson M, McKnite SH, Rees JN, Haman K, Shekar KC, Riess ML, Bates FS, et\u00a0al. 2016. Intracoronary poloxamer 188 Prevents reperfusion injury in a porcine model of st-segment elevation myocardial infarction. JACC. 1(4):224\u2013234.","journal-title":"JACC"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(94)33026-3"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1006\/abio.1996.0292"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5173(03)00386-7"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jps.20843"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-6915(97)00145-2"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2012.09.021"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1646460"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.3109\/03639045.2012.734510"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.02.009"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2010.12.139"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.indcrop.2013.07.054"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5037.2006.00149.x"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/jps.23451"},{"issue":"7","key":"e_1_3_2_28_1","first-page":"1028","article-title":"Nanoparticles of waste material of propolis and gelatin as a novel system for delivery of L-ascorbic acid","volume":"14","author":"de Francisco LMB","year":"2017","unstructured":"de Francisco LMB, Costa YTC, Outuki PM, Souza RP, Bonfim-Mendon\u00e7a PS, Novello CR, Consolaro MEL, Bruschi ML. 2017. Nanoparticles of waste material of propolis and gelatin as a novel system for delivery of L-ascorbic acid. CDD. 14(7):1028\u20131039.","journal-title":"CDD"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2017.11.046"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2017.02.016"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2017.05.040"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2015.10.026"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.3109\/03639045.2011.584387"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fbp.2016.12.014"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2005.11.043"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules16075875"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1080\/0005772X.1979.11097738"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbbm.2005.10.003"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2007.06.046"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2010.02.011"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2008.05.001"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2016.12.043"},{"issue":"34","key":"e_1_3_2_43_1","first-page":"45","article-title":"Yield-power law model mora accurately predicts mud rheology","volume":"91","author":"Hemphill T","year":"1993","unstructured":"Hemphill T, Campos W, Pilehvari A. 1993. Yield-power law model mora accurately predicts mud rheology. Oil Gas J. 91(34):45\u201350.","journal-title":"Oil Gas J"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2017.02.001"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/jps.2600521210"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tifs.2009.06.002"},{"key":"e_1_3_2_47_1","volume-title":"Validation of analytical procedures: text and methodology. International Conference on the Harmonisation of Technical Requiriments for the Registration of Pharmaceuticals for Human Use","author":"ICH.","year":"2005","unstructured":"ICH. 2005. Validation of analytical procedures: text and methodology. International Conference on the Harmonisation of Technical Requiriments for the Registration of Pharmaceuticals for Human Use. London."},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2009.01.006"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4628(19960919)61:12<2229::AID-APP24>3.0.CO;2-0"},{"key":"e_1_3_2_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(02)00176-X"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-7847.91114"},{"key":"e_1_3_2_52_1","first-page":"77","volume-title":"Controlled release delivery systems","author":"Korsmeyer RW","year":"1981","unstructured":"Korsmeyer RW, Peppas NA. 1981. Macromolecular and modeling aspects of swelling-controlled systems. In: Roseman TJ, Mansdorf SZ, editors. Controlled release delivery systems. New York: Marcel Dekker; p. 77\u201390."},{"key":"e_1_3_2_53_1","volume-title":"Desenvolvimento de Prepara\u00e7\u00f5es Cosm\u00e9ticas Contendo Vitamina C","author":"Krambeck K.","year":"2009","unstructured":"Krambeck K. 2009. Desenvolvimento de Prepara\u00e7\u00f5es Cosm\u00e9ticas Contendo Vitamina C. Porto: University of Porto."},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2006.09.004"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2005.04.006"},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2009.02.022"},{"key":"e_1_3_2_57_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp0730085"},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2006.05.006"},{"key":"e_1_3_2_59_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-89132012000100016"},{"key":"e_1_3_2_60_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.00-0547fje"},{"key":"e_1_3_2_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2013.12.008"},{"key":"e_1_3_2_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4807569"},{"key":"e_1_3_2_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0308-8146(99)00260-5"},{"key":"e_1_3_2_64_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00029.2006"},{"key":"e_1_3_2_65_1","volume-title":"Handbook of cosmetic science and technology","author":"Paye M","year":"2006","unstructured":"Paye M, Barel AO, Maibach HI. 2006. Handbook of cosmetic science and technology. 2nd ed. Boca Raton: Informa Health Care.","edition":"2"},{"key":"e_1_3_2_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2014.05.078"},{"key":"e_1_3_2_67_1","doi-asserted-by":"publisher","DOI":"10.1159\/000148223"},{"key":"e_1_3_2_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2014.05.079"},{"key":"e_1_3_2_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-3659(87)90035-6"},{"key":"e_1_3_2_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.indcrop.2013.06.015"},{"key":"e_1_3_2_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2017.07.029"},{"key":"e_1_3_2_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-2244(02)00012-2"},{"key":"e_1_3_2_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820060609"},{"key":"e_1_3_2_74_1","doi-asserted-by":"publisher","DOI":"10.5344\/ajev.1965.16.3.144"},{"key":"e_1_3_2_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfa.2012.11.009"},{"key":"e_1_3_2_76_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1984-82502015000400011"},{"key":"e_1_3_2_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2013.09.003"},{"key":"e_1_3_2_78_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-40422007000500046"},{"key":"e_1_3_2_79_1","doi-asserted-by":"publisher","DOI":"10.3109\/03639045.2013.817417"},{"key":"e_1_3_2_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2006.01.010"},{"key":"e_1_3_2_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2010.06.002"},{"key":"e_1_3_2_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2008.05.001"},{"key":"e_1_3_2_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.07.037"}],"container-title":["Pharmaceutical Development and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10837450.2019.1669643","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T18:42:21Z","timestamp":1731955341000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10837450.2019.1669643"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,3]]},"references-count":82,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1,2]]}},"alternative-id":["10.1080\/10837450.2019.1669643"],"URL":"https:\/\/doi.org\/10.1080\/10837450.2019.1669643","relation":{},"ISSN":["1083-7450","1097-9867"],"issn-type":[{"type":"print","value":"1083-7450"},{"type":"electronic","value":"1097-9867"}],"subject":[],"published":{"date-parts":[[2019,10,3]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iphd20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iphd20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-03-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-11","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}