{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T18:22:49Z","timestamp":1791138169549,"version":"4.1.0"},"reference-count":116,"publisher":"Informa UK Limited","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Investigation"],"published-print":{"date-parts":[[2004,1]]},"DOI":"10.1081\/cnv-200027144","type":"journal-article","created":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T20:03:30Z","timestamp":1096661010000},"page":"588-603","source":"Crossref","is-referenced-by-count":83,"title":["The Tuberous Sclerosis Complex Genes in Tumor Development"],"prefix":"10.1081","volume":"22","author":[{"given":"Baldwin C.","family":"Mak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond S.","family":"Yeung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2004,9,24]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1038\/35101031"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.genet.34.1.1"},{"key":"CIT0003","first-page":"81","volume":"1","author":"Bourneville D. M","year":"1880","journal-title":"Arch. Neurol. (Paris)"},{"key":"CIT0004","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1093\/oso\/9780195122107.003.0002","volume-title":"Tuberous Sclerosis Complex","author":"Gomez M. R","year":"1999"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1991.00530160068015"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1996.tb12086.x"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.24.14152"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1007\/BF00315012"},{"key":"CIT0009","first-page":"1201","volume":"149","author":"Bjornsson J.","year":"1996","journal-title":"Am. J. Pathol."},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.164.8.2104095"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1126\/science.277.5327.805"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90618-Z"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1038\/ng1294-328"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1159\/000059872"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1086\/316951"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1086\/302381"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1086\/302412"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/6.13.2265"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/3.10.1833"},{"key":"CIT0020","first-page":"1639","volume":"151","author":"Henske E. P.","year":"1997","journal-title":"Am. J. Pathol."},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5742(01)00058-8"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-03-3277"},{"key":"CIT0023","first-page":"4766","volume":"58","author":"Plank T. L.","year":"1998","journal-title":"Cancer Res."},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/7.6.1053"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)00333-6"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/10.25.2899"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.50.35647"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9861(02)00300-4"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C100136200"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/10.25.2889"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1038\/ncb839"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1007\/s003359900057"},{"key":"CIT0033","doi-asserted-by":"crossref","first-page":"F737","DOI":"10.1152\/ajprenal.2000.278.5.F737","volume":"278","author":"Murthy V.","year":"2000","journal-title":"Am. J. Physiol., Renal Physiol."},{"key":"CIT0034","first-page":"43","volume":"150","author":"Wienecke R.","year":"1997","journal-title":"Am. J. Pathol."},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2004.01.022"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1006\/mcbr.2001.0307"},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1093\/jnen\/60.7.711","volume":"60","author":"Catania M. G.","year":"2001","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1101\/gad.901101"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-437X(00)00191-X"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1038\/ncb840"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1038\/ncb847"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M202678200"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(02)00568-3"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M205838200"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.jcb.200206108"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M201142200"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/11.5.525"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.27.16409"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.10.6097"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1038\/ncb996"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1038\/ncb995"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1038\/ncb999"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1110003"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(03)00506-2"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C300226200"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(03)00220-X"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R000034200"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(02)00833-4"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(03)00114-X"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(02)00636-6"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81893-0"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(00)00599-6"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1093\/embo-reports\/kvf197"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1126\/science.1063518"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00929-2"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.17.11647"},{"key":"CIT0067","first-page":"5645","volume":"62","author":"Kenerson H. L.","year":"2002","journal-title":"Cancer Res."},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.24.1.200-216.2004"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0560.2001.028009470.x"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(03)00187-9"},{"key":"CIT0071","first-page":"5173","volume":"63","author":"El-Hashemite N.","year":"2003","journal-title":"Cancer Res."},{"key":"CIT0072","first-page":"2675","volume":"63","author":"Liu M. Y.","year":"2003","journal-title":"Cancer Res."},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1126\/science.1071549"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0004(01)01952-1"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1203245"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C200473200"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C000880200"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)00614-6"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(02)00864-3"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1038\/35010550"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1205962"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00482.2002"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200317222"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.32.20535"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M402790200"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1117"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M400957200"},{"key":"CIT0088","first-page":"9","volume":"9","author":"Nellist M.","year":"2002","journal-title":"J. Biol. Chem."},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C200510200"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M300862200"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C200499200"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.26.15653"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M203668200"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M207211200"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M303956200"},{"key":"CIT0096","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1093\/genetics\/147.4.1569","volume":"147","author":"Roberg K. J.","year":"1997","journal-title":"Genetics"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.232591899"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200210141"},{"key":"CIT0099","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1093\/genetics\/161.3.1053","volume":"161","author":"Matsumoto S.","year":"2002","journal-title":"Genetics"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M313874200"},{"key":"CIT0101","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(01)00226-X"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1038\/35050128"},{"key":"CIT0103","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.131.6.1421"},{"key":"CIT0104","doi-asserted-by":"publisher","DOI":"10.1002\/humu.10257"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1210\/mend.14.6.0446"},{"key":"CIT0106","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2004.02.082"},{"key":"CIT0107","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0308061100"},{"key":"CIT0108","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600110"},{"key":"CIT0109","doi-asserted-by":"publisher","DOI":"10.1038\/34432"},{"key":"CIT0110","doi-asserted-by":"publisher","DOI":"10.1126\/stke.2122003re15"},{"key":"CIT0111","doi-asserted-by":"publisher","DOI":"10.1111\/j.1356-9597.2004.00727.x"},{"key":"CIT0112","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.171060098"},{"key":"CIT0113","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.171076798"},{"key":"CIT0114","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.16.10608"},{"key":"CIT0115","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(03)00334-9"},{"key":"CIT0116","doi-asserted-by":"publisher","DOI":"10.1086\/342718"}],"container-title":["Cancer Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1081\/CNV-200027144","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,14]],"date-time":"2024-01-14T13:36:06Z","timestamp":1705239366000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1081\/CNV-200027144"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,1]]},"references-count":116,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2004,9,24]]},"published-print":{"date-parts":[[2004,1]]}},"alternative-id":["10.1081\/CNV-200027144"],"URL":"https:\/\/doi.org\/10.1081\/cnv-200027144","relation":{},"ISSN":["0735-7907","1532-4192"],"issn-type":[{"value":"0735-7907","type":"print"},{"value":"1532-4192","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,1]]}}}