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Biochemical analysis and total internal reflection fluorescence microscopy reveal that the subsequent physical interaction between APC and Dlg1 is required for polarization of the microtubule cytoskeleton.<\/jats:p>","DOI":"10.1083\/jcb.200412172","type":"journal-article","created":{"date-parts":[[2005,9,12]],"date-time":"2005-09-12T19:13:27Z","timestamp":1126552407000},"page":"895-901","update-policy":"https:\/\/doi.org\/10.1083\/jcb.crossmarkpolicy","source":"Crossref","is-referenced-by-count":251,"title":["Cdc42 and Par6\u2013PKC\u03b6 regulate the spatially localized association of Dlg1 and APC to control cell polarization"],"prefix":"10.1083","volume":"170","author":[{"given":"Sandrine","family":"Etienne-Manneville","sequence":"first","affiliation":[{"name":"1Medical Research Council Laboratory for Molecular Cell Biology and Cell Biology Unit, Cancer Research UK Oncogene and Signal Transduction Group"},{"name":"5Institut Curie, Centre National de la Recherche Scientifique, UMR144, Paris 75248, cedex 05, France"}]},{"given":"Jean-Baptiste","family":"Manneville","sequence":"additional","affiliation":[{"name":"3National Institute for Medical Research, London NW7 1AA, England, UK"},{"name":"5Institut Curie, Centre National de la Recherche Scientifique, UMR144, Paris 75248, cedex 05, France"}]},{"given":"Sarah","family":"Nicholls","sequence":"additional","affiliation":[{"name":"1Medical Research Council Laboratory for Molecular Cell Biology and Cell Biology Unit, Cancer Research UK Oncogene and Signal Transduction Group"}]},{"given":"Michael A.","family":"Ferenczi","sequence":"additional","affiliation":[{"name":"3National Institute for Medical Research, London NW7 1AA, England, UK"},{"name":"4Department of Biomedical Sciences, Imperial College, London SW7 2AZ, England, UK"}]},{"given":"Alan","family":"Hall","sequence":"additional","affiliation":[{"name":"1Medical Research Council Laboratory for Molecular Cell Biology and Cell Biology Unit, Cancer Research UK Oncogene and Signal Transduction Group"},{"name":"2Department of Biochemistry and Molecular Biology, University College London, London WC1E 6BT, England, UK"}]}],"member":"291","published-online":{"date-parts":[[2005,9,12]]},"reference":[{"key":"2023072217382493000_BIB1","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1242\/jcs.115.8.1583","volume":"115","year":"2002","journal-title":"J. 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