{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T12:48:29Z","timestamp":1791118109636,"version":"4.1.0"},"reference-count":67,"publisher":"Rockefeller University Press","issue":"3","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2000,10,30]]},"abstract":"<jats:p>Envoplakin and periplakin are two plakins that are precursors of the epidermal cornified envelope. We studied their distribution and interactions by transfection of primary human keratinocytes and other cells. Full-length periplakin localized to desmosomes, the interdesmosomal plasma membrane and intermediate filaments. Full length envoplakin also localized to desmosomes, but mainly accumulated in nuclear and cytoplasmic aggregates with associated intermediate filaments. The envoplakin rod domain was required for aggregation and the periplakin rod domain was necessary and sufficient to redistribute envoplakin to desmosomes and the cytoskeleton, confirming earlier predictions that the proteins can heterodimerize. The linker domain of each protein was required for intermediate filament association. Like the NH2 terminus of desmoplakin, that of periplakin localized to desmosomes; however, in addition, the periplakin NH2 terminus accumulated at cell surface microvilli in association with cortical actin. Endogenous periplakin was redistributed from microvilli when keratinocytes were treated with the actin disrupting drug Latrunculin B. We propose that whereas envoplakin and periplakin can localize independently to desmosomes, the distribution of envoplakin at the interdesmosomal plasma membrane depends on heterodimerization with periplakin and that the NH2 terminus of periplakin therefore plays a key role in forming the scaffold on which the cornified envelope is assembled.<\/jats:p>","DOI":"10.1083\/jcb.151.3.573","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T16:45:41Z","timestamp":1027701941000},"page":"573-586","update-policy":"https:\/\/doi.org\/10.1083\/jcb.crossmarkpolicy","source":"Crossref","is-referenced-by-count":86,"title":["Subcellular Distribution of Envoplakin and Periplakin"],"prefix":"10.1083","volume":"151","author":[{"given":"Teresa","family":"DiColandrea","sequence":"first","affiliation":[{"name":"aKeratinocyte Laboratory, Imperial Cancer Research Fund, London WC2A 3PX, England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadashi","family":"Karashima","sequence":"additional","affiliation":[{"name":"aKeratinocyte Laboratory, Imperial Cancer Research Fund, London WC2A 3PX, England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arto","family":"M\u00e4\u00e4tt\u00e4","sequence":"additional","affiliation":[{"name":"aKeratinocyte Laboratory, Imperial Cancer Research Fund, London WC2A 3PX, England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona M.","family":"Watt","sequence":"additional","affiliation":[{"name":"aKeratinocyte Laboratory, Imperial Cancer Research Fund, London WC2A 3PX, England"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"291","published-online":{"date-parts":[[2000,10,30]]},"reference":[{"key":"2023072902320863800_Ahoetal1998","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1006\/geno.1997.5188","article-title":"cDNA cloning, mRNA expression, and chromosomal mapping of human and mouse periplakin genes","volume":"48","author":"Aho","year":"1998","journal-title":"Genomics"},{"key":"2023072902320863800_N0x1e03260N0x28ef720","doi-asserted-by":"crossref","first-page":"3442","DOI":"10.1101\/gad.12.21.3442","article-title":"Not just scaffoldingplectin regulates actin dynamics in cultured cells","volume":"12","author":"Andr\u00e4","year":"1998","journal-title":"Genes Dev."},{"key":"2023072902320863800_Bornslaegeretal1996","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1083\/jcb.134.4.985","article-title":"Breaking the connectiondisplacement of the desmosomal plaque protein desmoplakin from cell\u2013cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly","volume":"134","author":"Bornslaeger","year":"1996","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_Foisneretal1988","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1083\/jcb.106.3.723","article-title":"Cytoskeleton-associated plectinin situ localization, in vitro reconstitution, and binding to immobilized intermediate filament proteins","volume":"106","author":"Foisner","year":"1988","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_FuchsandCleveland1998","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1126\/science.279.5350.514","article-title":"A structural scaffolding of intermediate filaments in health and disease","volume":"279","author":"Fuchs","year":"1998","journal-title":"Science"},{"key":"2023072902320863800_FuchsandYang1999","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0092-8674(00)80041-0","article-title":"Crossroads on cytoskeletal highways","volume":"98","author":"Fuchs","year":"1999","journal-title":"Cell."},{"key":"2023072902320863800_Fuchsetal1999","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1093\/hmg\/8.13.2461","article-title":"Unusual 5\u2032 transcript complexity of plectin isoformsnovel tissue-specific exons modulate actin binding activity","volume":"8","author":"Fuchs","year":"1999","journal-title":"Hum. Mol. Genet"},{"key":"2023072902320863800_Gandarillasetal1999","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1600-0625.1999.tb00350.x","article-title":"Evidence that apoptosis and terminal differentiation of epidermal keratinocytes are distinct processes","volume":"8","author":"Gandarillas","year":"1999","journal-title":"Exp. Dermatol."},{"key":"2023072902320863800_Geertsetal1999","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1083\/jcb.147.2.417","article-title":"Binding of integrin \u03b16\u03b24 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament binding","volume":"147","author":"Geerts","year":"1999","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_Greenetal1990","doi-asserted-by":"crossref","first-page":"11406","DOI":"10.1016\/S0021-9258(19)38608-9","article-title":"Structure of the human desmoplakins. Implications for function in the desmosomal plaque","volume":"265","author":"Green","year":"1990","journal-title":"J. Biol. Chem."},{"key":"2023072902320863800_Greenetal1992","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0141-8130(05)80004-2","article-title":"Comparative structural anaysis of desmoplakin, bullous pemphigoid antigen and plectinmembers of a new gene family involved in organization of intermediate filaments","volume":"14","author":"Green","year":"1992","journal-title":"J. Biol. Macromol."},{"key":"2023072902320863800_GregoryandBrown1998","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1083\/jcb.143.5.1271","article-title":"kakapo, a gene required for adhesion between and within cell layers in Drosophila, encodes a large cytoskeletal linker protein related to plectin and dystrophin","volume":"143","author":"Gregory","year":"1998","journal-title":"J. Cell Biol"},{"key":"2023072902320863800_Hatzfeldetal2000","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1083\/jcb.149.1.209","article-title":"The functions of plakophilin 1 in desmosome assembly and actin filament organization","volume":"149","author":"Hatzfeld","year":"2000","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_HerrmannandAebi2000","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0955-0674(99)00060-5","article-title":"Intermediate filaments and their associatesmulti-talented structural elements specifying cytoarchitecture and cytodynamics","volume":"12","author":"Herrmann","year":"2000","journal-title":"Curr. Opin. Cell Biol."},{"key":"2023072902320863800_Hochstenbachetal1992","doi-asserted-by":"crossref","first-page":"4734","DOI":"10.1073\/pnas.89.10.4734","article-title":"Endoplasmic reticulum resident protein of 90 kD associates with the T- and B-cell antigen receptors and major histocompatibility complex antigens during their assembly","volume":"89","author":"Hochstenbach","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"2023072902320863800_HouseweartandCleveland1998","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0955-0674(98)80091-4","article-title":"Intermediate filaments and their associated proteinsmultiple dynamic personalities","volume":"10","author":"Houseweart","year":"1998","journal-title":"Curr. Opin. Cell Biol."},{"key":"2023072902320863800_Huovilaetal1992","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1083\/jcb.118.6.1305","article-title":"Hepatitis B surface antigen assembles in a post-ER, pre-Golgi compartment","volume":"118","author":"Huovila","year":"1992","journal-title":"J. Cell Biol"},{"key":"2023072902320863800_Ishida-YamamotoandIizuka1998","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-0625.1998.tb00295.x","article-title":"Structural organization of cornified cell envelopes and alterations in inherited skin disorders","volume":"7","author":"Ishida-Yamamoto","year":"1998","journal-title":"Exp. Dermatol."},{"key":"2023072902320863800_Karakesisoglouetal2000","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1083\/jcb.149.1.195","article-title":"An epidermal plakin that integrates actin and microtubule networks at cellular junctions","volume":"149","author":"Karakesisoglou","year":"2000","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_Kiyokawaetal1998","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1046\/j.1523-1747.1998.00449.x","article-title":"Envoplakin and periplakin are components of the paraneoplastic pemphigus antigen complex","volume":"111","author":"Kiyokawa","year":"1998","journal-title":"J. Invest. Dermatol."},{"key":"2023072902320863800_Kouklisetal1994","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1083\/jcb.127.4.1049","article-title":"Making a connectiondirect binding between keratin intermediate filaments and desmosomal proteins","volume":"127","author":"Kouklis","year":"1994","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_Kowalczyketal1997","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1083\/jcb.139.3.773","article-title":"The amino-terminal domain of desmoplakin binds to plakoglobin and clusters desmosomal cadherin-plakoglobin complexes","volume":"139","author":"Kowalczyk","year":"1997","journal-title":"J. Cell Biol"},{"key":"2023072902320863800_Kowalczyketal1999","doi-asserted-by":"crossref","first-page":"18145","DOI":"10.1074\/jbc.274.26.18145","article-title":"The head domain of plakophilin-1 binds to desmoplakin and enhances its recruitment to desmosomes. Implications for cutaneous disease","volume":"274","author":"Kowalczyk","year":"1999","journal-title":"J. Biol. Chem."},{"key":"2023072902320863800_Lane1982","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1083\/jcb.92.3.665","article-title":"Monoclonal antibodies provide specific molecular markers for the study of epithelial tonofilament organization","volume":"92","author":"Lane","year":"1982","journal-title":"J. Cell Biol"},{"key":"2023072902320863800_Laneetal1985","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/j.1749-6632.1985.tb50415.x","article-title":"Keratin antigens in dfferentiating skin","volume":"455","author":"Lane","year":"1985","journal-title":"Ann. NY Acad. Sci"},{"key":"2023072902320863800_Leungetal1999","first-page":"41","article-title":"Microtubule actin cross-linking factor (MACF)a hybrid of dystonin and dystrophin that can interact with the actin and microtubule cytoskeletons","volume":"147","author":"Leung","year":"1999","journal-title":"J. Cell Biol"},{"key":"2023072902320863800_Levyetal1998","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1038\/sj.gt.3300689","article-title":"Optimised retroviral infection of human epidermal keratinocyteslong-term expression of transduced integrin gene following grafting on to SCID mice","volume":"5","author":"Levy","year":"1998","journal-title":"Gene Ther."},{"key":"2023072902320863800_Liuetal1996","doi-asserted-by":"crossref","first-page":"4278","DOI":"10.1073\/pnas.93.9.4278","article-title":"Human plectinorganization of the gene, sequence analysis, and chromosome localization (8q24)","volume":"93","author":"Liu","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"2023072902320863800_MaandSun1986","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1083\/jcb.103.1.41","article-title":"Differentiation-dependent changes in the solubility of a 195-kD protein in human epidermal keratinocytes","volume":"103","author":"Ma","year":"1986","journal-title":"J. Cell Biol"},{"key":"2023072902320863800_N0x1e03260N0x28f01a0","doi-asserted-by":"crossref","first-page":"19857","DOI":"10.1074\/jbc.M001028200","article-title":"Structure and regulation of the envoplakin gene","volume":"275","author":"M\u00e4\u00e4tt\u00e4","year":"2000","journal-title":"J. Biol. Chem."},{"key":"2023072902320863800_Mahoneyetal1998","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1046\/j.1523-1747.1998.00279.x","article-title":"The members of the plakin family of proteins recognized by paraneoplastic pemphigus antibodies include periplakin","volume":"111","author":"Mahoney","year":"1998","journal-title":"J. Invest. Dermatol."},{"key":"2023072902320863800_MarekovandSteinert1998","doi-asserted-by":"crossref","first-page":"17763","DOI":"10.1074\/jbc.273.28.17763","article-title":"Ceramides are bound to structural proteins of the human foreskin epidermal cornified cell envelope","volume":"273","author":"Marekov","year":"1998","journal-title":"J. Biol. Chem."},{"key":"2023072902320863800_Mengetal1997","doi-asserted-by":"crossref","first-page":"21495","DOI":"10.1074\/jbc.272.34.21495","article-title":"Two-hybrid analysis reveals fundamental differences in direct interactions between desmoplakin and cell type-specific intermediate filaments","volume":"272","author":"Meng","year":"1997","journal-title":"J. Biol. Chem."},{"key":"2023072902320863800_Morrisonetal1988","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0014-4827(88)90459-4","article-title":"The peanut lectin-binding glycoproteins of human epidermal keratinocytes","volume":"177","author":"Morrison","year":"1988","journal-title":"Exp. Cell Res"},{"key":"2023072902320863800_NemesandSteinert1999","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1038\/emm.1999.2","article-title":"Bricks and mortar of the epidermal barrier","volume":"31","author":"Nemes","year":"1999","journal-title":"Exp. Mol. Med."},{"key":"2023072902320863800_Nemesetal1999","doi-asserted-by":"crossref","first-page":"8402","DOI":"10.1073\/pnas.96.15.8402","article-title":"A novel function for transglutaminase 1attachment of long-chain \u03c9-hydroxyceramides to involucrin by ester bond formation","volume":"96","author":"Nemes","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"2023072902320863800_Nikolicetal1996","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1083\/jcb.134.6.1455","article-title":"Basic amino acid residue cluster within nuclear targeting sequence motif is essential for cytoplasmic plectin-vimentin network junctions","volume":"134","author":"Nikolic","year":"1996","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_OKeefeetal1989","doi-asserted-by":"crossref","first-page":"8310","DOI":"10.1016\/S0021-9258(18)83184-2","article-title":"Desmoplakin I and desmoplakin II. Purification and characterization","volume":"264","author":"O'Keefe","year":"1989","journal-title":"J. Biol. Chem."},{"key":"2023072902320863800_Peietal1991","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1093\/carcin\/12.2.277","article-title":"Two strains of human keratinocytes transfected with HPV16 DNAcomparison with the normal parental cells","volume":"12","author":"Pei","year":"1991","journal-title":"Carcinogenesis"},{"key":"2023072902320863800_Reichertetal1993","first-page":"107","article-title":"The cornified envelopea key structure of terminally differentiating keratinocytes","volume-title":"Molecular Biology of the Skin.","author":"Reichert","year":"1993"},{"key":"2023072902320863800_Romeroetal1999","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1111\/j.1600-0625.1999.tb00348.x","article-title":"Analysis of cultured keratinocytes from a transgenic mouse model of psoriasiseffects of suprabasal integrin expression on keratinocyte adhesion, proliferation and terminal differentiation","volume":"8","author":"Romero","year":"1999","journal-title":"Exp. Dermatol"},{"key":"2023072902320863800_RuhrbergandWatt1997","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/S0959-437X(97)80154-2","article-title":"The plakin familyversatile organizers of cytoskeletal architecture","volume":"7","author":"Ruhrberg","year":"1997","journal-title":"Curr. Opin. Genet. Dev"},{"key":"2023072902320863800_Ruhrbergetal1996","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1083\/jcb.134.3.715","article-title":"Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin","volume":"134","author":"Ruhrberg","year":"1996","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_Ruhrbergetal1997","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1083\/jcb.139.7.1835","article-title":"Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin","volume":"139","author":"Ruhrberg","year":"1997","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_Sarriaetal1994","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1242\/jcs.107.6.1593","article-title":"The presence or absence of a vimentin-type intermediate filament network affects the shape of the nucleus in human SW-13 cells","volume":"107","author":"Sarria","year":"1994","journal-title":"J. Cell Sci."},{"key":"2023072902320863800_Sawamuraetal1991","doi-asserted-by":"crossref","first-page":"17784","DOI":"10.1016\/S0021-9258(18)55195-4","article-title":"Human bullous pemphigoid antigen (BPAG1). Amino acid sequences deduced from cloned cDNAs predict biologically important peptide segments and protein domains","volume":"266","author":"Sawamura","year":"1991","journal-title":"J. Biol. Chem."},{"key":"2023072902320863800_Simon1994","first-page":"275","article-title":"The epidermal cornified cell envelope and its precursors","volume-title":"The Keratinocyte Handbook","author":"Simon","year":"1994"},{"key":"2023072902320863800_SimonandGreen1984","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/0092-8674(84)90032-1","article-title":"Participation of membrane-associated proteins in the formation of the cross-linked envelope of the keratinocyte","volume":"36","author":"Simon","year":"1984","journal-title":"Cell"},{"key":"2023072902320863800_Slotetal1991","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1083\/jcb.113.1.123","article-title":"Immuno-localization of the insulin regulatable glucose transport in brown adipose tissue of rat","volume":"113","author":"Slot","year":"1991","journal-title":"J. Cell Biol"},{"key":"2023072902320863800_SmithandFuchs1998","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1083\/jcb.141.5.1229","article-title":"Defining the interactions between intermediate filaments and desmosomes","volume":"141","author":"Smith","year":"1998","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_Spectoretal1999","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/(SICI)1097-0029(19991001)47:1<18::AID-JEMT3>3.0.CO;2-E","article-title":"New anti-actin drugs in the study of the organization and function of the actin cytoskeleton","volume":"47","author":"Spector","year":"1999","journal-title":"Microscopy Research and Technique."},{"key":"2023072902320863800_StappenbeckandGreen1992","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1083\/jcb.116.5.1197","article-title":"The desmoplakin carboxyl terminus coaligns with and specficially disrupts intermediate filament networks when expressed in cultured cells","volume":"116","author":"Stappenbeck","year":"1992","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_Stappenbecketal1993","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1083\/jcb.123.3.691","article-title":"Functional analysis of desmoplakin domainsspecification of the interaction with keratin versus vimentin intermediate filement networks","volume":"123","author":"Stappenbeck","year":"1993","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_N0x1e03260N0x28f0aa0","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1242\/jcs.113.3.483","article-title":"Dose-dependent linkage, assembly inhibition and disassembly of vimentin and cytokeratin 5\/14 filaments through plectin's intermediate filament-binding domain","volume":"113","author":"Steinb\u00f6ck","year":"2000","journal-title":"J. Cell Sci."},{"key":"2023072902320863800_SteinertandMarekov1995","doi-asserted-by":"crossref","first-page":"17702","DOI":"10.1074\/jbc.270.30.17702","article-title":"The proteins elafin, filaggrin, keratin intermediate filaments, loricrin and SPRs are isodipeptide cross-linked components of the human epidermal cornified cell envelope","volume":"270","author":"Steinert","year":"1995","journal-title":"J. Biol. Chem."},{"key":"2023072902320863800_SteinertandMarekov1997","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1074\/jbc.272.3.2021","article-title":"Involucrin is an early component in the assembly of the epidermal cornified cell envelope","volume":"270","author":"Steinert","year":"1997","journal-title":"J. Biol. Chem."},{"key":"2023072902320863800_SteinertandMarekov1999","doi-asserted-by":"crossref","first-page":"4247","DOI":"10.1091\/mbc.10.12.4247","article-title":"Initiation of assembly of the cell envelope barrier structure of stratified squamous epithelia","volume":"10","author":"Steinert","year":"1999","journal-title":"Mol. Biol. Cell."},{"key":"2023072902320863800_Studeretal1989","first-page":"253","article-title":"High pressure freezing comes of age","volume":"3","author":"Studer","year":"1989","journal-title":"Scanning Microsc. Suppl."},{"key":"2023072902320863800_StumpfandVolk1998","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1083\/jcb.143.5.1259","article-title":"Kakapo, a novel cytoskeletal-associated protein is essential for the restricted localization of the neuregulin-like factor, vein, at the muscle-tendon junction site","volume":"143","author":"Stumpf","year":"1998","journal-title":"J. Cell Biol"},{"key":"2023072902320863800_Svitkinaetal1996","first-page":"715","article-title":"Plectin sidearms mediate interaction of intermediate filaments with microtubules and other components of the cytoskeleton","volume":"134","author":"Svitkina","year":"1996","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_Tangetal1996","doi-asserted-by":"crossref","first-page":"9716","DOI":"10.1074\/jbc.271.16.9716","article-title":"Structural analysis of the predicted coiled-coiled rod domain of the cytoplasmic bullous pemphigoid antigen (BPAG1). Empirical localization of the N-terminal globular domain-rod boundary","volume":"271","author":"Tang","year":"1996","journal-title":"J. Biol. Chem."},{"key":"2023072902320863800_Wiche1998","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1242\/jcs.111.17.2477","article-title":"Role of plectin in cytoskeleton organization and dynamics","volume":"111","author":"Wiche","year":"1998","journal-title":"J. Cell Sci."},{"key":"2023072902320863800_Wicheetal1991","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1083\/jcb.114.1.83","article-title":"Cloning and sequencing of rat plectin indicates a 466-kD polypeptide chain with a three-domain structure based on a central alpha-helical coiled coil","volume":"114","author":"Wiche","year":"1991","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_Wicheetal1993","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1083\/jcb.121.3.607","article-title":"Expression of plectin mutant cDNA in cultured cells indicates a role of COOH-terminal domain in intermediate filament association","volume":"121","author":"Wiche","year":"1993","journal-title":"J. Cell Biol."},{"key":"2023072902320863800_Yangetal1996","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/S0092-8674(00)80138-5","article-title":"An essential cytoskeletal linker protein connecting actin microfilaments to intermediate filaments","volume":"86","author":"Yang","year":"1996","journal-title":"Cell."},{"key":"2023072902320863800_Yangetal1999","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0092-8674(00)81017-X","article-title":"Integrators of the cytoskeleton that stabilze microtubules","volume":"98","author":"Yang","year":"1999","journal-title":"Cell"},{"key":"2023072902320863800_Yonemuraetal1999","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1083\/jcb.145.7.1497","article-title":"Direct involvement of ezrin\/radixin\/moesin (ERM)-binding membrane proteins in the organization of microvilli in collaboration with activated ERM proteins","volume":"145","author":"Yonemura","year":"1999","journal-title":"J. Cell Biol"}],"container-title":["The Journal of Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/rupress.org\/jcb\/article-pdf\/151\/3\/573\/1860457\/0006038.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/rupress.org\/jcb\/article-pdf\/151\/3\/573\/1860457\/0006038.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,29]],"date-time":"2023-07-29T02:33:52Z","timestamp":1690598032000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jcb\/article\/151\/3\/573\/21298\/Subcellular-Distribution-of-Envoplakin-and"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,10,30]]},"references-count":67,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2000,10,30]]}},"URL":"https:\/\/doi.org\/10.1083\/jcb.151.3.573","relation":{},"ISSN":["0021-9525","1540-8140"],"issn-type":[{"value":"0021-9525","type":"print"},{"value":"1540-8140","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,10,30]]}}}