{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:33:42Z","timestamp":1791326022391,"version":"4.3.1"},"reference-count":37,"publisher":"Rockefeller University Press","issue":"6","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2004,9,13]]},"abstract":"<jats:p>GCM proteins constitute a small transcription factor family with a DNA-binding domain exhibiting a novel fold composed of two subdomains rigidly held together by coordination of one of two structural zinc cations. In all known cases, GCM proteins exert the role of master regulators: the prototypical family member determines gliogenesis in Drosophila melanogaster, whereas mammalian GCM proteins orchestrate divergent aspects of development and physiology in placenta, kidney, thymus, and parathyroid gland. Recent data point to an involvement of GCM proteins in different pathological contexts, such as preeclampsia, hyper- or hypoparathyroidism, and parathyroid gland tumors.<\/jats:p>","DOI":"10.1083\/jcb.200406097","type":"journal-article","created":{"date-parts":[[2004,9,8]],"date-time":"2004-09-08T01:33:09Z","timestamp":1094607189000},"page":"765-768","update-policy":"https:\/\/doi.org\/10.1083\/jcb.crossmarkpolicy","source":"Crossref","is-referenced-by-count":26,"title":["Impacts of a new transcription factor family"],"prefix":"10.1083","volume":"166","author":[{"given":"Said","family":"Hashemolhosseini","sequence":"first","affiliation":[{"name":"Institut fu\u0308r Biochemie, Universita\u0308t Erlangen-Nu\u0308rnberg, 91054 Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Wegner","sequence":"additional","affiliation":[{"name":"Institut fu\u0308r Biochemie, Universita\u0308t Erlangen-Nu\u0308rnberg, 91054 Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"291","published-online":{"date-parts":[[2004,9,7]]},"reference":[{"key":"2023072906415944300_BIB1","doi-asserted-by":"crossref","first-page":"14912","DOI":"10.1073\/pnas.93.25.14912","volume":"93","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"2023072906415944300_BIB2","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1006\/dbio.2002.0740","volume":"248","year":"2002","journal-title":"Dev. Biol."},{"key":"2023072906415944300_BIB3","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/77076","volume":"25","year":"2000","journal-title":"Nat. Genet."},{"key":"2023072906415944300_BIB4","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/(SICI)1097-0177(199904)214:4<303::AID-AJA3>3.0.CO;2-B","volume":"214","year":"1999","journal-title":"Dev. Dyn."},{"key":"2023072906415944300_BIB5","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1006\/dbio.1999.9511","volume":"216","year":"1999","journal-title":"Dev. Biol."},{"key":"2023072906415944300_BIB6","doi-asserted-by":"crossref","first-page":"4587","DOI":"10.1242\/dev.00647","volume":"130","year":"2003","journal-title":"Development."},{"key":"2023072906415944300_BIB7","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.placenta.2003.10.014","volume":"25","year":"2004","journal-title":"Placenta."},{"key":"2023072906415944300_BIB8","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0014-5793(02)03257-X","volume":"528","year":"2002","journal-title":"FEBS Lett."},{"key":"2023072906415944300_BIB9","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1093\/emboj\/cdg182","volume":"22","year":"2003","journal-title":"EMBO J."},{"key":"2023072906415944300_BIB10","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1046\/j.1365-2265.2002.01627.x","volume":"57","year":"2002","journal-title":"Clin. Endocrinol. (Oxf.)."},{"key":"2023072906415944300_BIB11","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1172\/JCI200113180","volume":"108","year":"2001","journal-title":"J. Clin. Invest."},{"key":"2023072906415944300_BIB12","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0925-4773(01)00333-1","volume":"103","year":"2001","journal-title":"Mech. Dev."},{"key":"2023072906415944300_BIB13","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/35018111","volume":"406","year":"2000","journal-title":"Nature."},{"key":"2023072906415944300_BIB14","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0925-4773(02)00239-3","volume":"118","year":"2002","journal-title":"Mech. Dev."},{"key":"2023072906415944300_BIB15","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0014-5793(03)01037-8","volume":"553","year":"2003","journal-title":"FEBS Lett."},{"key":"2023072906415944300_BIB16","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.jmb.2003.12.029","volume":"336","year":"2004","journal-title":"J. Mol. Biol."},{"key":"2023072906415944300_BIB17","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/0092-8674(95)90281-3","volume":"82","year":"1995","journal-title":"Cell."},{"key":"2023072906415944300_BIB18","doi-asserted-by":"crossref","first-page":"6027","DOI":"10.1242\/dev.00822","volume":"130","year":"2003","journal-title":"Development."},{"key":"2023072906415944300_BIB19","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1002\/bies.1129","volume":"23","year":"2001","journal-title":"Bioessays."},{"key":"2023072906415944300_BIB20","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/0092-8674(95)90280-5","volume":"82","year":"1995","journal-title":"Cell."},{"key":"2023072906415944300_BIB21","doi-asserted-by":"crossref","first-page":"4664","DOI":"10.1093\/emboj\/20.17.4664","volume":"20","year":"2001","journal-title":"EMBO J."},{"key":"2023072906415944300_BIB22","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0014-5793(98)01650-0","volume":"442","year":"1999","journal-title":"FEBS Lett."},{"key":"2023072906415944300_BIB23","doi-asserted-by":"crossref","first-page":"12364","DOI":"10.1073\/pnas.95.21.12364","volume":"95","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"2023072906415944300_BIB24","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1210\/jc.2003-030733","volume":"89","year":"2004","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"2023072906415944300_BIB25","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1177\/002215540004800704","volume":"48","year":"2000","journal-title":"J. Histochem. Cytochem."},{"key":"2023072906415944300_BIB26","doi-asserted-by":"crossref","first-page":"3957","DOI":"10.1242\/dev.129.16.3957","volume":"129","year":"2002","journal-title":"Development."},{"key":"2023072906415944300_BIB27","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0925-4773(99)00027-1","volume":"82","year":"1999","journal-title":"Mech. Dev."},{"key":"2023072906415944300_BIB28","doi-asserted-by":"crossref","first-page":"4739","DOI":"10.1073\/pnas.94.9.4739","volume":"94","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"2023072906415944300_BIB29","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1093\/nar\/26.10.2337","volume":"26","year":"1998","journal-title":"Nucleic Acids Res."},{"key":"2023072906415944300_BIB30","doi-asserted-by":"crossref","first-page":"2466","DOI":"10.1128\/MCB.20.7.2466-2474.2000","volume":"20","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"2023072906415944300_BIB31","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0925-4773(02)00095-3","volume":"115","year":"2002","journal-title":"Mech. Dev."},{"key":"2023072906415944300_BIB32","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1006\/dbio.2001.0342","volume":"236","year":"2001","journal-title":"Dev. Biol."},{"key":"2023072906415944300_BIB33","doi-asserted-by":"crossref","first-page":"4774","DOI":"10.1074\/jbc.275.7.4774","volume":"275","year":"2000","journal-title":"J. Biol. Chem."},{"key":"2023072906415944300_BIB34","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S0959-437X(02)00327-1","volume":"12","year":"2002","journal-title":"Curr. Opin. Genet. Dev."},{"key":"2023072906415944300_BIB35","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1242\/dev.122.1.131","volume":"122","year":"1996","journal-title":"Development."},{"key":"2023072906415944300_BIB36","doi-asserted-by":"crossref","first-page":"32279","DOI":"10.1074\/jbc.274.45.32279","volume":"274","year":"1999","journal-title":"J. Biol. Chem."},{"key":"2023072906415944300_BIB37","doi-asserted-by":"crossref","first-page":"50062","DOI":"10.1074\/jbc.M209316200","volume":"277","year":"2002","journal-title":"J. Biol. Chem."}],"container-title":["The Journal of Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/rupress.org\/jcb\/article-pdf\/166\/6\/765\/1870996\/jcb1666765.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/rupress.org\/jcb\/article-pdf\/166\/6\/765\/1870996\/jcb1666765.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,29]],"date-time":"2023-07-29T06:43:12Z","timestamp":1690612992000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jcb\/article\/166\/6\/765\/51273\/Impacts-of-a-new-transcription-factor-family"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,9,7]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,9,13]]}},"URL":"https:\/\/doi.org\/10.1083\/jcb.200406097","relation":{},"ISSN":["1540-8140","0021-9525"],"issn-type":[{"value":"1540-8140","type":"electronic"},{"value":"0021-9525","type":"print"}],"subject":[],"published":{"date-parts":[[2004,9,7]]}}}