{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:00:10Z","timestamp":1760644810340},"reference-count":0,"publisher":"Rockefeller University Press","issue":"3","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1975,9,1]]},"abstract":"<jats:p>The morphology of the tight junction of rat thyroid epithelium was examined in freeze-fractured material fixed in glutaraldehyde and briefly glycerinated. In normal thyroids the overall appearance of this junctional specialization resembled that of other cell types in many respects. Short-term changes in thyroid activity and hypophysectomy for 3 wk did not obviously affect the appearance of tight junctions. Feeding of the goitrogen, thiouracil, which stimulates secretion of thyroid-stimulating hormone, resulted in the appearance of some very narrow and some very wide, tight junctions or sometimes junctions with both wide and narrow regions within the same cell.<\/jats:p>","DOI":"10.1083\/jcb.66.3.657","type":"journal-article","created":{"date-parts":[[2004,5,14]],"date-time":"2004-05-14T23:04:59Z","timestamp":1084575899000},"page":"657-663","update-policy":"http:\/\/dx.doi.org\/10.1083\/jcb.crossmarkpolicy","source":"Crossref","is-referenced-by-count":44,"title":["Changes in tight junctions of thyroid epithelium with changes in thyroid activity."],"prefix":"10.1083","volume":"66","author":[{"given":"L W","family":"Tice","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S H","family":"Wollman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R C","family":"Carter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1975,9,1]]},"container-title":["The Journal of cell biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/rupress.org\/jcb\/article-pdf\/66\/3\/657\/1630462\/657.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/rupress.org\/jcb\/article-pdf\/66\/3\/657\/1630462\/657.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T06:49:44Z","timestamp":1690181384000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jcb\/article\/66\/3\/657\/29525\/Changes-in-tight-junctions-of-thyroid-epithelium"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,9,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1975,9,1]]}},"URL":"https:\/\/doi.org\/10.1083\/jcb.66.3.657","relation":{},"ISSN":["0021-9525","1540-8140"],"issn-type":[{"value":"0021-9525","type":"print"},{"value":"1540-8140","type":"electronic"}],"subject":[],"published":{"date-parts":[[1975,9,1]]}}}