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This impacts the quality of T cell responses and the ability to limit viral persistence. Our studies provide unexpected insights into novel interplays between innate and adaptive immune effectors, and define the critical requirements for efficient control of viral persistence.<\/jats:p>","DOI":"10.1084\/jem.20091193","type":"journal-article","created":{"date-parts":[[2010,5,31]],"date-time":"2010-05-31T20:54:27Z","timestamp":1275339267000},"page":"1333-1343","update-policy":"https:\/\/doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":185,"title":["Innate immunity defines the capacity of antiviral T cells to limit persistent infection"],"prefix":"10.1084","volume":"207","author":[{"given":"Daniel M.","family":"Andrews","sequence":"first","affiliation":[{"name":"Immunology and Virology Program, Centre for Ophthalmology and Visual Science 1 , 2"},{"name":"University Department of Medicine, University of Western Australia, Nedlands, Western Australia 6009, Australia 1 , 2"},{"name":"Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia 6009, Australia 3"}]},{"given":"Marie J.","family":"Estcourt","sequence":"additional","affiliation":[{"name":"Immunology and Virology Program, Centre for Ophthalmology and Visual Science 1 , 2"},{"name":"University Department of Medicine, University of Western Australia, Nedlands, Western Australia 6009, Australia 1 , 2"},{"name":"Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia 6009, Australia 3"}]},{"given":"Christopher E.","family":"Andoniou","sequence":"additional","affiliation":[{"name":"Immunology and Virology Program, Centre for Ophthalmology and Visual Science 1 , 2"},{"name":"University Department of Medicine, University of Western Australia, Nedlands, Western Australia 6009, Australia 1 , 2"},{"name":"Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia 6009, Australia 3"}]},{"given":"Matthew E.","family":"Wikstrom","sequence":"additional","affiliation":[{"name":"Immunology and 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