{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:01:16Z","timestamp":1760979676520},"reference-count":0,"publisher":"Rockefeller University Press","issue":"6","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1955,12,1]]},"abstract":"<jats:p>The injection of rabbit antidog-placenta serum in 11 dogs resulted in an acute nephritis which was fatal within a month in 4, progressed to a chronic disease in 5, and healed in 2 animals. The nephritis produced in 5 dogs by the injection of rabbit antidog-kidney serum was comparable to that following the injection of antiplacenta serum.<\/jats:p>\n               <jats:p>The manifestations of the acute disease included edema, hypertension, proteinuria, cylindruria, hematuria, nitrogen retention, hypoalbuminemia, hypercholesterolemia, increased erythrocyte sedimentation rate, and anemia. The non-fatal chronic nephritis was characterized by proteinuria, cylindruria, and hematuria. With the onset of renal failure elevation of the blood urea nitrogen again occurred.<\/jats:p>\n               <jats:p>Antiplacenta serum did not cause abortion when injected into pregnant dogs, nor did pregnancy modify the subsequent development of nephritis.<\/jats:p>","DOI":"10.1084\/jem.102.6.789","type":"journal-article","created":{"date-parts":[[2004,6,22]],"date-time":"2004-06-22T18:35:50Z","timestamp":1087929350000},"page":"789-805","update-policy":"http:\/\/dx.doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":35,"title":["GLOMERULONEPHRITIS PRODUCED IN DOGS BY SPECIFIC ANTISERA"],"prefix":"10.1084","volume":"102","author":[{"given":"Beatrice Carrier","family":"Seegal","sequence":"first","affiliation":[{"name":"From the Department of Microbiology, College of Physicians and Surgeons and the Columbia University Research Service, Goldwater Memorial Hospital, Columbia University, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margo W.","family":"Hasson","sequence":"additional","affiliation":[{"name":"From the Department of Microbiology, College of Physicians and Surgeons and the Columbia University Research Service, Goldwater Memorial Hospital, Columbia University, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evelyn C.","family":"Gaynor","sequence":"additional","affiliation":[{"name":"From the Department of Microbiology, College of Physicians and Surgeons and the Columbia University Research Service, Goldwater Memorial Hospital, Columbia University, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mildred S.","family":"Rothenberg","sequence":"additional","affiliation":[{"name":"From the Department of Microbiology, College of Physicians and Surgeons and the Columbia University Research Service, Goldwater Memorial Hospital, Columbia University, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1955,12,1]]},"container-title":["The Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/rupress.org\/jem\/article-pdf\/102\/6\/789\/1643909\/789.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/rupress.org\/jem\/article-pdf\/102\/6\/789\/1643909\/789.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T17:48:34Z","timestamp":1690220914000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/102\/6\/789\/2202\/GLOMERULONEPHRITIS-PRODUCED-IN-DOGS-BY-SPECIFIC"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1955,12,1]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1955,12,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.102.6.789","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1955,12,1]]}}}