{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T08:48:35Z","timestamp":1784191715183,"version":"3.55.0"},"reference-count":0,"publisher":"Rockefeller University Press","issue":"5","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1959,11,1]]},"abstract":"<jats:p>The sequential cytological changes which develop in tissue culture cells infected with adenovirus types 5 and 7 are described and compared with those produced by adenovirus types 1, 2, 3, and 4. The evidence that is presented indicates that types 1, 2, and 5 belong to one major subdivision of the adenovirus group and types 3, 4, and 7 to another. That the host cell nucleus is the principal site of adenovirus synthesis has been confirmed by fluorescent antibody studies. They have demonstrated the occurrence of type-specific adenovirus antigen in the characteristic intranuclear inclusions and other virus-induced structures reported to contain virus-like particles or shown by electronmicroscopy.<\/jats:p>","DOI":"10.1084\/jem.110.5.827","type":"journal-article","created":{"date-parts":[[2004,6,22]],"date-time":"2004-06-22T20:51:07Z","timestamp":1087937467000},"page":"827-844","update-policy":"https:\/\/doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":60,"title":["SEQUENTIAL CELLULAR CHANGES PRODUCED BY TYPES 5 AND 7 ADENOVIRUSES IN H<scp>E<\/scp>L<scp>A<\/scp> CELLS AND IN HUMAN AMNIOTIC CELLS"],"prefix":"10.1084","volume":"110","author":[{"given":"Georgiana S.","family":"Boyer","sequence":"first","affiliation":[{"name":"From the Departments of Preventive Medicine, Medicine and Pediatrics, School of Medicine, Western Reserve University, and the University Hospitals, Cleveland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Floyd W.","family":"Denny","sequence":"additional","affiliation":[{"name":"From the Departments of Preventive Medicine, Medicine and Pediatrics, School of Medicine, Western Reserve University, and the University Hospitals, Cleveland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold S.","family":"Ginsberg","sequence":"additional","affiliation":[{"name":"From the Departments of Preventive Medicine, Medicine and Pediatrics, School of Medicine, Western Reserve University, and the University Hospitals, Cleveland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"291","published-online":{"date-parts":[[1959,11,1]]},"container-title":["The Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/rupress.org\/jem\/article-pdf\/110\/5\/827\/1647561\/827.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/rupress.org\/jem\/article-pdf\/110\/5\/827\/1647561\/827.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T18:44:46Z","timestamp":1690224286000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/110\/5\/827\/2714\/SEQUENTIAL-CELLULAR-CHANGES-PRODUCED-BY-TYPES-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1959,11,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1959,11,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.110.5.827","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1959,11,1]]}}}