{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:20:43Z","timestamp":1759962043413},"reference-count":0,"publisher":"Rockefeller University Press","issue":"3","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1964,3,1]]},"abstract":"<jats:p>1. Immunochemical cross-reactivity, but not identity, has been demonstrated between bovine parathyroid hormone and an antigen in biologically active extracts of human parathyroid tissue by quantitative C' fixation and C' fixation inhibition.<\/jats:p>\n               <jats:p>2. An antigen that fixes C' with rabbit antibody to bovine parathyroid hormone has been found in urea extracts of six human non-parathyroid neoplasms associated with a hypercalcemic syndrome mimicking primary hyperparathyroidism. Comparable extracts of control tissues and other tumors were serologically negative.<\/jats:p>\n               <jats:p>3. It is concluded that the tumor antigen is parathyroid hormone or a very closely related protein, and that its production by these neoplasms was the cause of the hypercalcemic syndrome in these six patients.<\/jats:p>","DOI":"10.1084\/jem.119.3.467","type":"journal-article","created":{"date-parts":[[2004,6,22]],"date-time":"2004-06-22T20:51:07Z","timestamp":1087937467000},"page":"467-484","update-policy":"http:\/\/dx.doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":112,"title":["IMMUNOCHEMICAL IDENTIFICATION OF PARATHYROID HORMONE IN NON-PARATHYROID NEOPLASMS ASSOCIATED WITH HYPERCALCEMIA"],"prefix":"10.1084","volume":"119","author":[{"suffix":"Jr.","given":"Armen H.","family":"Tashjian","sequence":"first","affiliation":[{"name":"From the Biological Research Laboratories, Harvard School of Dental Medicine, Department of Pharmacology, Harvard Medical School, Boston, and the Graduate Department of Biochemistry, Brandeis University, Waltham"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence","family":"Levine","sequence":"additional","affiliation":[{"name":"From the Biological Research Laboratories, Harvard School of Dental Medicine, Department of Pharmacology, Harvard Medical School, Boston, and the Graduate Department of Biochemistry, Brandeis University, Waltham"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul L.","family":"Munson","sequence":"additional","affiliation":[{"name":"From the Biological Research Laboratories, Harvard School of Dental Medicine, Department of Pharmacology, Harvard Medical School, Boston, and the Graduate Department of Biochemistry, Brandeis University, Waltham"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1964,3,1]]},"container-title":["The Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/rupress.org\/jem\/article-pdf\/119\/3\/467\/1650087\/467.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/rupress.org\/jem\/article-pdf\/119\/3\/467\/1650087\/467.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T19:35:08Z","timestamp":1690227308000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/119\/3\/467\/3714\/IMMUNOCHEMICAL-IDENTIFICATION-OF-PARATHYROID"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1964,3,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1964,3,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.119.3.467","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1964,3,1]]}}}