{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T20:35:55Z","timestamp":1781901355921,"version":"3.54.5"},"reference-count":0,"publisher":"Rockefeller University Press","issue":"5","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1965,5,1]]},"abstract":"<jats:p>A hemagglutination method employing tanned human O erythrocytes sensitized with purified Group A streptococcal polysaccharide has been developed to measure A polysaccharide antibody in antistreptococcal rabbit and human sera.<\/jats:p>\n               <jats:p>The reaction of sensitized RBC with known Group A streptococcal rabbit antisera, inhibition of hemagglutination with A polysaccharide, and abolition of hemagglutination and hemagglutination-inhibition by exposure of polysaccharide antigen to A enzyme, which destroys the specific immunologic determinant of A carbohydrate, were utilized to demonstrate the specificity of this hemagglutinating system.<\/jats:p>\n               <jats:p>The results of A polysaccharide antibody determinations on sera from normal persons, patients convalescent from streptococcal infection, and patients with non-suppurative streptococcal sequelae are presented.<\/jats:p>","DOI":"10.1084\/jem.121.5.793","type":"journal-article","created":{"date-parts":[[2004,6,22]],"date-time":"2004-06-22T20:51:07Z","timestamp":1087937467000},"page":"793-806","update-policy":"https:\/\/doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":21,"title":["THE DETERMINATION OF ANTIBODY TO GROUP A STREPTOCOCCAL POLYSACCHARIDE IN HUMAN SERA BY HEMAGGLUTINATION"],"prefix":"10.1084","volume":"121","author":[{"given":"Willard C.","family":"Schmidt","sequence":"first","affiliation":[{"name":"From the Departments of Pediatrics, Preventive Medicine, and Microbiology, Cleveland Metropolitan General Hospital, and Western Reserve University School of Medicine, Cleveland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorothy J.","family":"Moore","sequence":"additional","affiliation":[{"name":"From the Departments of Pediatrics, Preventive Medicine, and Microbiology, Cleveland Metropolitan General Hospital, and Western Reserve University School of Medicine, Cleveland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"291","published-online":{"date-parts":[[1965,5,1]]},"container-title":["The Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/rupress.org\/jem\/article-pdf\/121\/5\/793\/1650742\/793.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/rupress.org\/jem\/article-pdf\/121\/5\/793\/1650742\/793.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T19:44:30Z","timestamp":1690227870000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/121\/5\/793\/3836\/THE-DETERMINATION-OF-ANTIBODY-TO-GROUP-A"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1965,5,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1965,5,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.121.5.793","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1965,5,1]]}}}