{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T10:39:59Z","timestamp":1698835199997},"reference-count":0,"publisher":"Rockefeller University Press","issue":"5","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1914,11,1]]},"abstract":"<jats:p>1. Intact bacteria probably resist tryptic digestion because of the absence of an exposed protein substrate.<\/jats:p>\n               <jats:p>2. Dried organisms resist digestion in a degree proportional to their content of unsaturated lipoids.<\/jats:p>\n               <jats:p>3. Lipoidal extractives reduce the resistance to tryptic digestion.<\/jats:p>\n               <jats:p>4. The extracted lipoids (saponified) are antitryptic in a degree proportional to their unsaturation.<\/jats:p>\n               <jats:p>5. The inactivation of the antiferment in Gram-negative organisms is probably due to changes in the degree of lipoidal dispersion.<\/jats:p>\n               <jats:p>6. Bacteria adsorb lipoids from the serum when incubated at 37\u00b0 C. Such organisms when dried are found to be more resistant to tryptic digestion than untreated organisms.<\/jats:p>","DOI":"10.1084\/jem.20.5.452","type":"journal-article","created":{"date-parts":[[2004,6,24]],"date-time":"2004-06-24T23:49:02Z","timestamp":1088120942000},"page":"452-467","update-policy":"http:\/\/dx.doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["BACTERIAL ANTIFERMENTS"],"prefix":"10.1084","volume":"20","author":[{"given":"James W.","family":"Jobling","sequence":"first","affiliation":[{"name":"From the Department of Pathology of the College of Physicians and Surgeons, Columbia University, New York."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Petersen","sequence":"additional","affiliation":[{"name":"From the Department of Pathology of the College of Physicians and Surgeons, Columbia University, New York."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1914,11,1]]},"container-title":["Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/20\/5\/452\/1208953\/452.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/20\/5\/452\/1208953\/452.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T16:21:33Z","timestamp":1601742093000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/20\/5\/452\/8504\/BACTERIAL-ANTIFERMENTS-STUDIES-ON-FERMENT-ACTION"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1914,11,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1914,11,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.20.5.452","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1914,11,1]]}}}