{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T12:39:50Z","timestamp":1648903190150},"reference-count":0,"publisher":"Rockefeller University Press","issue":"5","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1914,11,1]]},"abstract":"<jats:p>1. The antitryptic titer of the serum can be increased by subcutaneous injections of serum lipoids (antitrypsin) and of the lipoids from egg yolk.<\/jats:p>\n               <jats:p>2. Animals so injected show a relative immunity to acute anaphylactic shock (two minimum lethal doses).<\/jats:p>\n               <jats:p>3. Extraction of lipoids contained in antigens increases the toxicity of the antigen when injected into a sensitized animal.<\/jats:p>\n               <jats:p>4. Sublethal doses of soap solutions injected simultaneously with the antigen (purified horse serum albumen) prevent anaphylactic shock.<\/jats:p>\n               <jats:p>5. The refractory state following anaphylactic shock is related in part to an increase in the antitryptic titer of the serum.<\/jats:p>","DOI":"10.1084\/jem.20.5.468","type":"journal-article","created":{"date-parts":[[2004,6,24]],"date-time":"2004-06-24T23:49:02Z","timestamp":1088120942000},"page":"468-476","update-policy":"http:\/\/dx.doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["LIPOIDS AS INHIBITORS OF ANAPHYLACTIC SHOCK"],"prefix":"10.1084","volume":"20","author":[{"given":"James W.","family":"Jobling","sequence":"first","affiliation":[{"name":"From the Department of Pathology of the College of Physicians and Surgeons, Columbia University, New York."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Petersen","sequence":"additional","affiliation":[{"name":"From the Department of Pathology of the College of Physicians and Surgeons, Columbia University, New York."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1914,11,1]]},"container-title":["Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/20\/5\/468\/1208934\/468.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/20\/5\/468\/1208934\/468.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T16:19:50Z","timestamp":1601741990000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/20\/5\/468\/8506\/LIPOIDS-AS-INHIBITORS-OF-ANAPHYLACTIC-SHOCK"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1914,11,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1914,11,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.20.5.468","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1914,11,1]]}}}