{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T19:14:06Z","timestamp":1759778046510,"version":"3.41.2"},"reference-count":11,"publisher":"Rockefeller University Press","issue":"4","license":[{"start":{"date-parts":[[2021,3,12]],"date-time":"2021-03-12T00:00:00Z","timestamp":1615507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.rupress.org\/terms\/"},{"start":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T00:00:00Z","timestamp":1633305600000},"content-version":"vor","delay-in-days":206,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"}],"content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,4,5]]},"abstract":"<jats:p>In a 1937 issue of JEM, Carrel (1937. J. Exp. Med.https:\/\/doi.org\/10.1084\/jem.65.4.515) described a technique for culturing whole living organs outside the body. Here, Ingber reviews how this work led to a series of scientific, engineering, and medical breakthroughs that continue to this day.<\/jats:p>","DOI":"10.1084\/jem.20201756","type":"journal-article","created":{"date-parts":[[2021,3,12]],"date-time":"2021-03-12T14:36:47Z","timestamp":1615559807000},"update-policy":"https:\/\/doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Enabling out-of-body experiences for living organs"],"prefix":"10.1084","volume":"218","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4319-6520","authenticated-orcid":true,"given":"Donald E.","family":"Ingber","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[2021,3,12]]},"reference":[{"key":"2023072622520468400_bib1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.65.4.515","author":"Carrel","year":"1937","journal-title":"J. Exp. Med."},{"key":"2023072622520468400_bib2","doi-asserted-by":"publisher","DOI":"10.1126\/science.81.2112.621","author":"Carrel","year":"1935","journal-title":"Science."},{"key":"2023072622520468400_bib3","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196304)16:4&lt;453::aid-cncr2820160407&gt;3.0.co;2-y","author":"Folkman","year":"1963","journal-title":"Cancer."},{"key":"2023072622520468400_bib4","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-019-0498-9","author":"Herland","year":"2020","journal-title":"Nat. Biomed. Eng."},{"key":"2023072622520468400_bib5","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-019-0325-y","author":"Homan","year":"2019","journal-title":"Nat. Methods."},{"key":"2023072622520468400_bib6","doi-asserted-by":"publisher","DOI":"10.1126\/science.1188302","author":"Huh","year":"2010","journal-title":"Science."},{"key":"2023072622520468400_bib7","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3004249","author":"Huh","year":"2012","journal-title":"Sci. Transl. Med."},{"key":"2023072622520468400_bib8","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202002030","author":"Ingber","year":"2020","journal-title":"Adv. Sci."},{"key":"2023072622520468400_bib9","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1522193112","author":"Kim","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"2023072622520468400_bib10","doi-asserted-by":"publisher","DOI":"10.1084\/jem.62.3.409","author":"Lindbergh","year":"1935","journal-title":"J. Exp. Med."},{"key":"2023072622520468400_bib11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8191.2002.tb01210.x","author":"Stephenson","year":"2002","journal-title":"J. Card. Surg."}],"container-title":["Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/rupress.org\/jem\/article-pdf\/doi\/10.1084\/jem.20201756\/1791751\/jem_20201756.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/rupress.org\/jem\/article-pdf\/doi\/10.1084\/jem.20201756\/1791751\/jem_20201756.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,26]],"date-time":"2023-07-26T22:52:28Z","timestamp":1690411948000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/218\/4\/e20201756\/211881\/Enabling-out-of-body-experiences-for-living"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,12]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4,5]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.20201756","relation":{},"ISSN":["0022-1007","1540-9538"],"issn-type":[{"type":"print","value":"0022-1007"},{"type":"electronic","value":"1540-9538"}],"subject":[],"published":{"date-parts":[[2021,3,12]]},"article-number":"e20201756"}}