{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T13:15:03Z","timestamp":1762175703097},"reference-count":0,"publisher":"Rockefeller University Press","issue":"2","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1915,8,1]]},"abstract":"<jats:p>1. The intravenous injection of trypsin in dogs results in a shock similar in many respects to anaphylactic and peptone shock.<\/jats:p>\n               <jats:p>2. The injection is followed by a marked rise of serum protease and lipase.<\/jats:p>\n               <jats:p>3. The antiferment usually shows a distinct drop in titer, with a recovery following in from four to twenty-four hours.<\/jats:p>\n               <jats:p>4. The non-coagulable nitrogen shows no constant alteration, but is never greatly changed in amount.<\/jats:p>\n               <jats:p>5. Inactivated preparations were in some respects followed by symptoms similar to those following the injection of the active preparation.<\/jats:p>\n               <jats:p>6. Subcutaneous and gastric absorption was practically without effect.<\/jats:p>\n               <jats:p>7. Intestinal absorption was followed by an increase in serum protease without evidence of intoxication, or by typical symptoms of acute poisoning.<\/jats:p>\n               <jats:p>8. The leucocyte curve bears no constant relation to the serum protease or lipase.<\/jats:p>","DOI":"10.1084\/jem.22.2.141","type":"journal-article","created":{"date-parts":[[2004,6,17]],"date-time":"2004-06-17T22:31:16Z","timestamp":1087511476000},"page":"141-153","update-policy":"http:\/\/dx.doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["SERUM FERMENTS AND ANTIFERMENT DURING TRYPSIN SHOCK"],"prefix":"10.1084","volume":"22","author":[{"given":"James W.","family":"Jobling","sequence":"first","affiliation":[{"name":"From the Department of Pathology, Medical Department, Vanderbilt University, Nashville."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Petersen","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, Medical Department, Vanderbilt University, Nashville."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. A.","family":"Eggstein","sequence":"additional","affiliation":[{"name":"From the Department of Pathology, Medical Department, Vanderbilt University, Nashville."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1915,8,1]]},"container-title":["Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/22\/2\/141\/1173717\/141.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/22\/2\/141\/1173717\/141.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T11:04:03Z","timestamp":1601723043000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/22\/2\/141\/8615\/SERUM-FERMENTS-AND-ANTIFERMENT-DURING-TRYPSIN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1915,8,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1915,8,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.22.2.141","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1915,8,1]]}}}