{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T11:03:37Z","timestamp":1758279817325},"reference-count":0,"publisher":"Rockefeller University Press","issue":"3","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1923,3,1]]},"abstract":"<jats:p>Chemical studies of the blood and urine of four dogs following pyloric obstruction are reported.<\/jats:p>\n               <jats:p>The observations of other workers that a fall in chlorides and a rise in CO2-combining power of the plasma occur, are confirmed.<\/jats:p>\n               <jats:p>There is also a marked rise in the non-protein nitrogen of the blood, consisting mainly of urea nitrogen and undetermined nitrogen.<\/jats:p>\n               <jats:p>The fall in chlorides is not due to the loss of chlorides in the gastric juice. The chlorine is probably bound somewhere in the process of protein destruction.<\/jats:p>\n               <jats:p>There is a close relation between the fall in chlorides and the protein destruction.<\/jats:p>\n               <jats:p>A study of tetany should include the protein metabolism as well as that of the inorganic salts, since it seems possible that the tetany is due to protein split-products and not to the alkalosis.<\/jats:p>\n               <jats:p>The chemical changes following pyloric obstruction are essentially the same as those following high intestinal obstruction.<\/jats:p>","DOI":"10.1084\/jem.37.3.377","type":"journal-article","created":{"date-parts":[[2004,6,17]],"date-time":"2004-06-17T23:20:47Z","timestamp":1087514447000},"page":"377-381","update-policy":"http:\/\/dx.doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":29,"title":["CHEMICAL CHANGES IN THE BLOOD OF THE DOG AFTER PYLORIC OBSTRUCTION"],"prefix":"10.1084","volume":"37","author":[{"given":"Russell L.","family":"Haden","sequence":"first","affiliation":[{"name":"From the University of Kansas School of Medicine, Kansas City, Kansas."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas G.","family":"Orr","sequence":"additional","affiliation":[{"name":"From the University of Kansas School of Medicine, Kansas City, Kansas."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1923,3,1]]},"container-title":["Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/37\/3\/377\/1176488\/377.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/37\/3\/377\/1176488\/377.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T11:42:57Z","timestamp":1601725377000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/37\/3\/377\/9137\/CHEMICAL-CHANGES-IN-THE-BLOOD-OF-THE-DOG-AFTER"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1923,3,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1923,3,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.37.3.377","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1923,3,1]]}}}