{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T15:24:41Z","timestamp":1648567481770},"reference-count":0,"publisher":"Rockefeller University Press","issue":"6","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1931,12,1]]},"abstract":"<jats:p>These experiments show:<\/jats:p>\n               <jats:p>1. That the surface tension of normal blood serum is considerably lowered by standing undisturbed for a period of 1 hour (time-drop).<\/jats:p>\n               <jats:p>2. That the greatest time-drop recorded is with serum diluted approximately 10,000 times in fresh serum, and 50,000 times in heated serum.<\/jats:p>\n               <jats:p>3. That immune serum is not affected in the same manner by heat as is normal serum. Syphilitic serum and anti-sheep cell rabbit serum behave similarly in this respect.<\/jats:p>\n               <jats:p>4. That serum albumin is much more readily soluble in alkaline buffer solutions than globulin is, and that globulin from normal serum ionizes more than that from syphilitic serum.<\/jats:p>\n               <jats:p>Further investigations are being made in an effort to determine why the proteins aggregate or dissociate under the influence of the factors under consideration.<\/jats:p>","DOI":"10.1084\/jem.54.6.859","type":"journal-article","created":{"date-parts":[[2004,6,18]],"date-time":"2004-06-18T06:19:10Z","timestamp":1087539550000},"page":"859-873","update-policy":"http:\/\/dx.doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["STUDIES ON THE SPECIFIC CHARACTERISTICS OF SYPHILITIC BLOOD PROTEINS"],"prefix":"10.1084","volume":"54","author":[{"given":"S. T.","family":"Walton","sequence":"first","affiliation":[{"name":"From the Department of Laboratories, Henry Ford Hospital, Detroit"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1931,12,1]]},"container-title":["Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/54\/6\/859\/1179436\/859.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/54\/6\/859\/1179436\/859.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T12:38:09Z","timestamp":1601728689000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/54\/6\/859\/52812\/STUDIES-ON-THE-SPECIFIC-CHARACTERISTICS-OF"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1931,12,1]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1931,12,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.54.6.859","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1931,12,1]]}}}