{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:13:26Z","timestamp":1760188406936},"reference-count":0,"publisher":"Rockefeller University Press","issue":"2","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1932,2,1]]},"abstract":"<jats:p>1. Normal serum, used in cultures for preparation of the streptolysin, modifies the properties of the streptolysin, causing delayed hemolysis, increased filterability, resistance to oxidation or reduction, and absence of antigenicity.<\/jats:p>\n               <jats:p>1. Streptolysin prepared without serum is an active antigen.<\/jats:p>\n               <jats:p>3. Similar temperatures are required to destroy the antigenic activity of serum-free streptolysin and the skin reactivity of Dick toxin.<\/jats:p>\n               <jats:p>4. Scarlet fever antitoxin contains antistreptolysin which does not neutralise serum streptolysin and which can be detected only by titration against serum-free streptolysin.<\/jats:p>\n               <jats:p>5. The antihemolysin which neutralises serum-free streptolysin is species-specific but not type-specific.<\/jats:p>","DOI":"10.1084\/jem.55.2.267","type":"journal-article","created":{"date-parts":[[2004,6,18]],"date-time":"2004-06-18T06:19:10Z","timestamp":1087539550000},"page":"267-280","update-policy":"http:\/\/dx.doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":88,"title":["ANTIGENIC STREPTOCOCCAL HEMOLYSIN"],"prefix":"10.1084","volume":"55","author":[{"given":"E. W.","family":"Todd","sequence":"first","affiliation":[{"name":"From the Belmont Laboratories (London County Council), Sutton, Surrey, England"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1932,2,1]]},"container-title":["Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/55\/2\/267\/1140275\/267.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/55\/2\/267\/1140275\/267.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T08:15:46Z","timestamp":1601712946000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/55\/2\/267\/10241\/ANTIGENIC-STREPTOCOCCAL-HEMOLYSIN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1932,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1932,2,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.55.2.267","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1932,2,1]]}}}