{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T20:42:54Z","timestamp":1704919374634},"reference-count":0,"publisher":"Rockefeller University Press","issue":"4","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1936,10,1]]},"abstract":"<jats:p>1. Sensitized guinea pigs injected with normal rabbit or guinea pig serum previous to intravenous inoculation of antigen may be protected against a few lethal doses of antigen. The protection is greater with foreign than with homologous serum and appears to be related roughly to the amount of serum introduced.<\/jats:p>\n               <jats:p>2. Sensitized guinea pigs injected with antibody-containing serum preliminary to intravenous injection of antigen, show no greater refractoriness to anaphylaxis than do those injected with normal serum.<\/jats:p>\n               <jats:p>3. Moreover, in many instances, the injection of an excess of antibody into the circulation of sensitized guinea pigs, leads to an increased susceptibility of these animals to anaphylaxis.<\/jats:p>\n               <jats:p>4. These results indicate that an excess of circulating antibody is not responsible for a state of antianaphylaxis, but on the contrary, may contribute toward the anaphylactic reaction itself.<\/jats:p>","DOI":"10.1084\/jem.64.4.641","type":"journal-article","created":{"date-parts":[[2004,6,21]],"date-time":"2004-06-21T23:43:35Z","timestamp":1087861415000},"page":"641-655","update-policy":"http:\/\/dx.doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["THE RELATION BETWEEN ANTIANAPHYLAXIS AND ANTIBODY BALANCE"],"prefix":"10.1084","volume":"64","author":[{"given":"Marion C.","family":"Morris","sequence":"first","affiliation":[{"name":"From the Department of Bacteriology and Immunology, Washington University School of Medicine, St. Louis"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1936,10,1]]},"container-title":["Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/64\/4\/641\/1398902\/641.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/64\/4\/641\/1398902\/641.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T11:40:44Z","timestamp":1601984444000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/64\/4\/641\/3474\/THE-RELATION-BETWEEN-ANTIANAPHYLAXIS-AND-ANTIBODY"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1936,10,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1936,10,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.64.4.641","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1936,10,1]]}}}