{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T10:16:13Z","timestamp":1770718573544,"version":"3.49.0"},"reference-count":0,"publisher":"Rockefeller University Press","issue":"2","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1937,8,1]]},"abstract":"<jats:p>A Plasmodium knowlesi infection in rhesus monkeys is almost invariably fatal. This infection, however, may be made chronic by the early administration of antimalarial drugs. The animals then will harbor a chronic infection for an indefinite period. The serum taken from monkeys with chronic infection and injected into those suffering from an acute attack was found to have a definite depressing effect upon the course of the experimental disease. In some instances death was prevented and the acute infection changed into a chronic form; in others, the course of the experimental disease was prolonged.<\/jats:p>\n               <jats:p>In a similar manner the serum from monkeys harboring a chronic Plasmodium inui infection, when injected into monkeys suffering from an acute attack due to this parasite, was found to be effective in reducing the intensity of the primary infection.<\/jats:p>\n               <jats:p>The data presented indicate that protective antibodies are produced in the serum of monkeys during experimental malaria infection.<\/jats:p>","DOI":"10.1084\/jem.66.2.177","type":"journal-article","created":{"date-parts":[[2004,6,21]],"date-time":"2004-06-21T23:43:35Z","timestamp":1087861415000},"page":"177-190","update-policy":"https:\/\/doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":64,"title":["DEMONSTRATION OF PASSIVE IMMUNITY IN EXPERIMENTAL MONKEY MALARIA"],"prefix":"10.1084","volume":"66","author":[{"given":"L. T.","family":"Coggeshall","sequence":"first","affiliation":[{"name":"From the Laboratories of the International Health Division, The Rockefeller Foundation, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. W.","family":"Kumm","sequence":"additional","affiliation":[{"name":"From the Laboratories of the International Health Division, The Rockefeller Foundation, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1937,8,1]]},"container-title":["Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/66\/2\/177\/1181012\/177.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/66\/2\/177\/1181012\/177.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T13:04:53Z","timestamp":1601730293000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/66\/2\/177\/3627\/DEMONSTRATION-OF-PASSIVE-IMMUNITY-IN-EXPERIMENTAL"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1937,8,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1937,8,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.66.2.177","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1937,8,1]]}}}