{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T08:26:32Z","timestamp":1758875192345},"reference-count":0,"publisher":"Rockefeller University Press","issue":"1","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1939,1,1]]},"abstract":"<jats:p>Vascularization of the cornea of the rat in the absence of antecedent pathology is probably a specific and the most reliable criterion of riboflavin deficiency.<\/jats:p>\n               <jats:p>Its initiation and repair may be used for testing the biological activity of compounds structurally related to riboflavin.<\/jats:p>\n               <jats:p>The facts that the invading capillaries are easily visible in the living animal and that the growth and regression of the blood vessels are under dietary control and for a considerable period of time unaccompanied by other pathological reactions, make this method very suitable for the study of problems related to capillary growth.<\/jats:p>\n               <jats:p>We believe that the best hypothesis in explanation is that the vascularization is a response to asphyxia of the tunica propria.<\/jats:p>","DOI":"10.1084\/jem.69.1.1","type":"journal-article","created":{"date-parts":[[2004,6,21]],"date-time":"2004-06-21T19:01:21Z","timestamp":1087844481000},"page":"1-12","update-policy":"http:\/\/dx.doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":63,"title":["VASCULARIZATION OF THE CORNEA OF THE RAT IN RIBOFLAVIN DEFICIENCY, WITH A NOTE ON CORNEAL VASCULARIZATION IN VITAMIN A DEFICIENCY"],"prefix":"10.1084","volume":"69","author":[{"given":"O. A.","family":"Bessey","sequence":"first","affiliation":[{"name":"From the Dental School and Department of Pathology, The Harvard Medical School, Boston"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. B.","family":"Wolbach","sequence":"additional","affiliation":[{"name":"From the Dental School and Department of Pathology, The Harvard Medical School, Boston"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1939,1,1]]},"container-title":["Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/69\/1\/1\/1181427\/1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/69\/1\/1\/1181427\/1.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T13:12:39Z","timestamp":1601730759000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/69\/1\/1\/52839\/VASCULARIZATION-OF-THE-CORNEA-OF-THE-RAT-IN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1939,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1939,1,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.69.1.1","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1939,1,1]]}}}