{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T08:38:34Z","timestamp":1648715914256},"reference-count":0,"publisher":"Rockefeller University Press","issue":"6","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1943,12,1]]},"abstract":"<jats:p>In mice vaccinated subcutaneously with different doses of virulent W.E.E. virus or with formolized vaccine, neutralizing and complement-fixing antibodies paralleled resistance to some extent yet appeared in groups in which resistance remained undetectable, persisted at a similar maximum level in spite of different titers of resistance, and after resistance had become negligible.<\/jats:p>\n               <jats:p>In mice vaccinated subcutaneously with different doses of virulent St. Louis encephalitis virus or with formolized vaccine, neutralizing and complement-fixing antibodies bore little relation to resistance. Neutralizing antibodies appeared only in the group showing resistance but not until resistance was diminishing. Complement-fixing antibodies developed equally well in groups with or without resistance.<\/jats:p>","DOI":"10.1084\/jem.78.6.447","type":"journal-article","created":{"date-parts":[[2004,6,21]],"date-time":"2004-06-21T23:43:35Z","timestamp":1087861415000},"page":"447-463","update-policy":"http:\/\/dx.doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["NEUTRALIZING AND COMPLEMENT-FIXING ANTIBODY PRODUCTION AND RESISTANCE FOLLOWING VACCINATION IN EXPERIMENTAL ENCEPHALITIS INFECTIONS"],"prefix":"10.1084","volume":"78","author":[{"given":"J.","family":"Casals","sequence":"first","affiliation":[{"name":"From the Laboratories of The Rockefeller Institute for Medical Research, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1943,12,1]]},"container-title":["Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/78\/6\/447\/1182747\/447.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/78\/6\/447\/1182747\/447.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T13:40:07Z","timestamp":1601732407000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/78\/6\/447\/4742\/NEUTRALIZING-AND-COMPLEMENTFIXING-ANTIBODY"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1943,12,1]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1943,12,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.78.6.447","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1943,12,1]]}}}