{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:12:37Z","timestamp":1787505157490,"version":"build-2736575974"},"reference-count":0,"publisher":"Rockefeller University Press","issue":"3","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1944,9,1]]},"abstract":"<jats:p>1. The symptoms, history of tick bite, characteristic fever curve, and white blood cell picture should enable the physician to make a diagnosis of Colorado tick fever in nearly every case.<\/jats:p>\n                  <jats:p>2. The typical white blood cell picture is a depression of the total leucocytes with a shift to the left of the granulocytes. Basophilic cytoplasmic bodies appear occasionally in lymphocytes 3 to 4 days after clinical recovery.<\/jats:p>\n                  <jats:p>3. The disease can be transmitted serially in human beings by parenteral injection of blood or serum. Such transfers have not resulted in decreased or increased virulence.<\/jats:p>\n                  <jats:p>4. The naturally acquired and experimental cases of Colorado tick fever are identical in their manifestations.<\/jats:p>\n                  <jats:p>5. An attack of Colorado tick fever confers a degree of definite immunity to the disease.<\/jats:p>\n                  <jats:p>6. Colorado tick fever is not a mild form of Rocky Mountain spotted fever since individuals immunized with ground tick vaccine against Rocky Mountain spotted fever are still susceptible to Colorado tick fever.<\/jats:p>\n                  <jats:p>7. Adult Dermacentor andersoni ticks allowed to feed on typical cases, then carried through to a new generation and fed on susceptible adults, failed to transmit the disease.<\/jats:p>\n                  <jats:p>8. Colorado tick fever has been successfully transmitted to an experimental animal, the golden hamster.<\/jats:p>","DOI":"10.1084\/jem.80.3.165","type":"journal-article","created":{"date-parts":[[2004,6,21]],"date-time":"2004-06-21T19:43:35Z","timestamp":1087847015000},"page":"165-188","update-policy":"https:\/\/doi.org\/10.1084\/jem.crossmarkpolicy","source":"Crossref","is-referenced-by-count":27,"title":["THE EXPERIMENTAL TRANSMISSION OF COLORADO TICK FEVER"],"prefix":"10.1084","volume":"80","author":[{"given":"Lloyd","family":"Florio","sequence":"first","affiliation":[{"name":"From the Department of Public Health and Laboratory Diagnosis, University of Colorado School of Medicine, Denver"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mabel O.","family":"Stewart","sequence":"additional","affiliation":[{"name":"From the Department of Public Health and Laboratory Diagnosis, University of Colorado School of Medicine, Denver"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward R.","family":"Mugrage","sequence":"additional","affiliation":[{"name":"From the Department of Public Health and Laboratory Diagnosis, University of Colorado School of Medicine, Denver"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"291","published-online":{"date-parts":[[1944,9,1]]},"container-title":["Journal of Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/80\/3\/165\/1183012\/165.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/rupress.org\/jem\/article-pdf\/80\/3\/165\/1183012\/165.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T09:44:26Z","timestamp":1601718266000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jem\/article\/80\/3\/165\/4803\/THE-EXPERIMENTAL-TRANSMISSION-OF-COLORADO-TICK"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1944,9,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1944,9,1]]}},"URL":"https:\/\/doi.org\/10.1084\/jem.80.3.165","relation":{},"ISSN":["1540-9538","0022-1007"],"issn-type":[{"value":"1540-9538","type":"electronic"},{"value":"0022-1007","type":"print"}],"subject":[],"published":{"date-parts":[[1944,9,1]]}}}