{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T10:28:17Z","timestamp":1758709697444},"reference-count":0,"publisher":"Rockefeller University Press","issue":"5","content-domain":{"domain":["rupress.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1972,11,1]]},"abstract":"<jats:p>We measured the internal potassium activity, aiK, and membrane potential, Em, simultaneously in 111 R2 giant neurons of Aplysia californica. aiK was 165.3 \u00b1 3.4 mM, Em was -47.8 \u00b1 0.9 mv, and EK calculated using the Nernst equation was -76.9 \u00b1 0.05 mv. Such values were maintained for as long as 6 hr of continuous recording in untreated cells, aiK fell exponentially after the following treatments: cooling to 0.5\u00b0\u20134\u00b0C, ouabain, zero external potassium, 2,4-dinitrophenol, and cyanide. The effects of cooling and zero potassium were reversible. Potassium permeability was calculated from net potassium flux using the constant field equation and ranged from 2.6 to 18.5 x 10-8 cm\/sec. We conclude that potassium is actively transported into this neuron against a 30\u201340 mv electrochemical gradient.<\/jats:p>","DOI":"10.1085\/jgp.60.5.519","type":"journal-article","created":{"date-parts":[[2004,5,13]],"date-time":"2004-05-13T22:45:45Z","timestamp":1084488345000},"page":"519-533","update-policy":"http:\/\/dx.doi.org\/10.1085\/jgp.crossmarkpolicy","source":"Crossref","is-referenced-by-count":29,"title":["Active Transport of Potassium by the Giant Neuron of the <i>Aplysia<\/i> Abdominal Ganglion"],"prefix":"10.1085","volume":"60","author":[{"given":"J. M.","family":"Russell","sequence":"first","affiliation":[{"name":"From the Departments of Pharmacology, Physiology, and Medicine, University of Utah College of Medicine, Salt Lake City, Utah 84112"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M.","family":"Brown","sequence":"additional","affiliation":[{"name":"From the Departments of Pharmacology, Physiology, and Medicine, University of Utah College of Medicine, Salt Lake City, Utah 84112"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"291","published-online":{"date-parts":[[1972,11,1]]},"container-title":["The Journal of General Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/rupress.org\/jgp\/article-pdf\/60\/5\/519\/1809701\/519.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/rupress.org\/jgp\/article-pdf\/60\/5\/519\/1809701\/519.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T11:16:00Z","timestamp":1690456560000},"score":1,"resource":{"primary":{"URL":"https:\/\/rupress.org\/jgp\/article\/60\/5\/519\/31149\/Active-Transport-of-Potassium-by-the-Giant-Neuron"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,11,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1972,11,1]]}},"URL":"https:\/\/doi.org\/10.1085\/jgp.60.5.519","relation":{},"ISSN":["1540-7748","0022-1295"],"issn-type":[{"value":"1540-7748","type":"electronic"},{"value":"0022-1295","type":"print"}],"subject":[],"published":{"date-parts":[[1972,11,1]]}}}