{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:00:09Z","timestamp":1784192409666,"version":"3.55.0"},"reference-count":13,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T00:00:00Z","timestamp":1420156800000},"content-version":"unspecified","delay-in-days":5511,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[1999,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0195941700073021_abs1\"><jats:title>Objective:<\/jats:title><jats:p>To characterize the epidemiological relationships among<jats:italic>Stenotrophomonas maltophilia<\/jats:italic>isolates in the neonatology unit of our institution over a 4-month period in which an increased number of isolates was observed.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700073021_abs2\"><jats:title>Setting:<\/jats:title><jats:p>The neonatology ward in a 2,000-bed university hospital in Madrid, Spain.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700073021_abs3\"><jats:title>Design:<\/jats:title><jats:p>A retrospective molecular epidemiological analysis using three different typing methods, arbitrarily primed polymerase chain reaction (PCR), pulsed-field gel electrophoresis, and enterobacterial repetitive intergenic consensus-PCR, was performed with 11 isolates obtained from seven neonates over a 4-month period. Presumed unrelated isolates also were included as controls. A similarity dendrogram was obtained, to analyze the genetic relatedness among the isolates.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700073021_abs4\"><jats:title>Results:<\/jats:title><jats:p>All isolates from the neonates, except one, showed a remarkably high homology among their typing patterns for the three methods assayed and clustered in the relatedness dendrogram at 96% similarity. The unrelated strains selected as controls were unclustered. The index case was considered to be a newborn who had an<jats:italic>S maltophilia<\/jats:italic>isolate from a culture drawn on the day of admission to the neonatology unit and which was included in the clustered similarity group.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700073021_abs5\"><jats:title>Conclusions:<\/jats:title><jats:p>Such a high genetic similarity among the isolates, together with the presence of an index case who had been colonized or infected by<jats:italic>S maltophilia<\/jats:italic>before arrival at our institution, constitutes the first evidence of nosocomial cross-transmission of this microorganism.<\/jats:p><\/jats:sec>","DOI":"10.1086\/501590","type":"journal-article","created":{"date-parts":[[2006,2,3]],"date-time":"2006-02-03T21:31:03Z","timestamp":1139002263000},"page":"816-820","source":"Crossref","is-referenced-by-count":34,"title":["Evidence of Nosocomial<i>Stenotrophomonas Maltophilia<\/i>Cross-Infection in a Neonatology Unit Analyzed by Three Molecular Typing Methods"],"prefix":"10.1017","volume":"20","author":[{"given":"Dar\u00edo Garc\u00eda","family":"de 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