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An understanding of the epidemiology, clinical manifestations, and management of the more likely candidate agents is critical to limiting morbidity and mortality from a biological event. Effective response requires an increased index of suspicion for unusual diseases or syndromes, with prompt reporting to health authorities to facilitate recognition of an outbreak and subsequent intervention. Hospital epidemiology programs will play a crucial role in this effort.<\/jats:p>","DOI":"10.1086\/501700","type":"journal-article","created":{"date-parts":[[2006,2,7]],"date-time":"2006-02-07T20:02:23Z","timestamp":1139342543000},"page":"53-56","source":"Crossref","is-referenced-by-count":40,"title":["The Threat of Biological Terrorism: A Public Health and Infection Control Reality"],"prefix":"10.1017","volume":"21","author":[{"given":"Robert J.","family":"Leggiadro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,1,2]]},"reference":[{"key":"S0195941700071873_ref012","first-page":"617","article-title":"Fatal human plague\u2014 Arizona and Colorado, 1996","volume":"46","year":"1997","journal-title":"MMWR"},{"key":"S0195941700071873_ref004","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03550050074036"},{"key":"S0195941700071873_ref015","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-198311000-00019"},{"key":"S0195941700071873_ref003","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03550050061035"},{"key":"S0195941700071873_ref002","doi-asserted-by":"publisher","DOI":"10.3201\/eid0403.980341"},{"key":"S0195941700071873_ref014","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198507000-00006"},{"key":"S0195941700071873_ref016","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1542\/peds.87.1.124a","article-title":"Tetracycline for Rocky Mountain spotted fever","volume":"87","author":"Leggiadro","year":"1991","journal-title":"Pediatrics"},{"key":"S0195941700071873_ref007","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.158.5.429"},{"key":"S0195941700071873_ref009","doi-asserted-by":"publisher","DOI":"10.1126\/science.7973702"},{"key":"S0195941700071873_ref005","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.22.2127"},{"key":"S0195941700071873_ref001","doi-asserted-by":"publisher","DOI":"10.3201\/eid0403.980340"},{"key":"S0195941700071873_ref010","first-page":"69","article-title":"Bioterrorism alleging use of anthrax and interim guidelines for management\u2014United States, 1998","volume":"48","year":"1999","journal-title":"MMWR"},{"key":"S0195941700071873_ref006","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/19.6.1009"},{"key":"S0195941700071873_ref013","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1542\/peds.69.6.762","article-title":"Pediatric plague","volume":"69","author":"Mann","year":"1982","journal-title":"Pediatrics"},{"key":"S0195941700071873_ref008","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.18.1735"},{"key":"S0195941700071873_ref011","first-page":"1","article-title":"Prevention of plague: recommendations of the Advisory Committee on Immunization Practices (ACIP)","volume":"45","year":"1996","journal-title":"MMWR"}],"container-title":["Infection Control &amp; Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0195941700071873","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,6]],"date-time":"2023-05-06T11:53:40Z","timestamp":1683374020000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0195941700071873\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,1]]}},"alternative-id":["S0195941700071873"],"URL":"https:\/\/doi.org\/10.1086\/501700","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,1]]}}}