{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:20:15Z","timestamp":1761128415546},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T00:00:00Z","timestamp":1420156800000},"content-version":"unspecified","delay-in-days":4780,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2001,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0195941700074531_abs1\"><jats:title>Objective:<\/jats:title><jats:p>To compare the prevalence of nasal<jats:italic>Staphylococcus aureus<\/jats:italic>carriage among outpatients receiving allergen-injection immunotherapy with the prevalence among healthy controls and to determine predictors of nasal<jats:italic>S aureus<\/jats:italic>carriage.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700074531_abs2\"><jats:title>Design:<\/jats:title><jats:p>Survey.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700074531_abs3\"><jats:title>Setting:<\/jats:title><jats:p>Allergy clinic of a university hospital.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700074531_abs4\"><jats:title>Participants:<\/jats:title><jats:p>A volunteer sample consisting of 45 outpatients undergoing desensitization therapy and 84 first- and second-year medical students.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700074531_abs5\"><jats:title>Results:<\/jats:title><jats:p>The nasal<jats:italic>S aureus<\/jats:italic>carriage rate was significantly higher among patients (46.7%) than among students (26.2%;<jats:italic>P<\/jats:italic>=.019). In a multivariate model adjusted for age and gender, the presence of atopic dermatitis or eczema was the only independent predictor of nasal S<jats:italic>aureus<\/jats:italic>carriage (odds ratio [OR], 4.4; 95% confidence interval [CI<jats:sub>95<\/jats:sub>], 1.2-16.0;<jats:italic>P<\/jats:italic>=.02). The only other participant characteristic associated with nasal<jats:italic>S aureus<\/jats:italic>carriage was immunotherapy with allergen injections (OR, 1.98; CI<jats:sub>95<\/jats:sub>, 0.7-6.0), but this association did not reach statistical significance (<jats:italic>P<\/jats:italic>=.23). The probability of nasal<jats:italic>S aureus<\/jats:italic>carriage was 88.9% for patients receiving allergen injections and having atopic dermatitis or eczema, and 36.1% for patients receiving allergen injections without atopic dermatitis or eczema.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700074531_abs6\"><jats:title>Conclusions:<\/jats:title><jats:p>Patients undergoing desensitization have a higher nasal carriage rate of<jats:italic>S aureus.<\/jats:italic>However, factors other than the regular use of needles, and in particular abnormalities related to the atopic constitution of these patients, may predispose this population for<jats:italic>S aureus<\/jats:italic>carriage.<\/jats:p><\/jats:sec>","DOI":"10.1086\/501857","type":"journal-article","created":{"date-parts":[[2006,2,17]],"date-time":"2006-02-17T20:45:23Z","timestamp":1140209123000},"page":"741-745","source":"Crossref","is-referenced-by-count":8,"title":["Nasal Carriage of<i>Staphylococcus aureus<\/i>Among Patients Receiving Allergen-Injection Immunotherapy: Associated Factors and Quantitative Nasal Cultures"],"prefix":"10.1017","volume":"22","author":[{"given":"Stefano","family":"Bassetti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donnie P.","family":"Dunagan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Ralph B.","family":"D'Agostino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"Sherertz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,1,2]]},"reference":[{"key":"S0195941700074531_ref009","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/162.6.1400"},{"key":"S0195941700074531_ref008","doi-asserted-by":"publisher","DOI":"10.1177\/106002809803200104"},{"key":"S0195941700074531_ref015","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12500072"},{"key":"S0195941700074531_ref018","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1128\/IAI.64.1.310-318.1996","article-title":"Staphylococcus aureus binding to human nasal mucin","volume":"64","author":"Shuter","year":"1996","journal-title":"Infect Immun"},{"key":"S0195941700074531_ref001","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-6553(96)90026-7"},{"key":"S0195941700074531_ref005","doi-asserted-by":"publisher","DOI":"10.1001\/jama.279.8.593"},{"key":"S0195941700074531_ref007","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1128\/CMR.10.3.505","article-title":"Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks","volume":"10","author":"Kluytmans","year":"1997","journal-title":"Clin Microbiol Rev"},{"key":"S0195941700074531_ref011","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1977.01640060076008"},{"key":"S0195941700074531_ref002","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-6553(99)70031-3"},{"key":"S0195941700074531_ref013","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.133.11.1463"},{"key":"S0195941700074531_ref019","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2000.104256"},{"key":"S0195941700074531_ref010","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199107000-00007"},{"key":"S0195941700074531_ref003","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1994.03510440058033"},{"key":"S0195941700074531_ref004","doi-asserted-by":"publisher","DOI":"10.1086\/501572"},{"key":"S0195941700074531_ref006","first-page":"1165","article-title":"Staphylococcus aureus with reduced susceptibility to vancomycin\u2014Illinois, 1999","volume":"48","year":"2000","journal-title":"MMWR"},{"key":"S0195941700074531_ref014","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1995.tb03366.x"},{"key":"S0195941700074531_ref017","first-page":"L1203","article-title":"Mucoglycoprotein hypersecretion in allergic rhinitis and cystic fibrosis","volume":"273","author":"Yuta","year":"1997","journal-title":"Am J Physiol"},{"key":"S0195941700074531_ref016","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.1995.tb01134.x"},{"key":"S0195941700074531_ref012","first-page":"235","article-title":"Carriage rate of Staphylococcus aureus among patients receiving allergy injections","volume":"45","author":"Kirmani","year":"1980","journal-title":"Ann Allergy"}],"container-title":["Infection Control &amp; 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