{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T10:22:40Z","timestamp":1776680560768,"version":"3.51.2"},"reference-count":32,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2016,6,21]],"date-time":"2016-06-21T00:00:00Z","timestamp":1466467200000},"content-version":"unspecified","delay-in-days":4038,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2005,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0899823X0019840X_abs1\"><jats:title>Objective:<\/jats:title><jats:p>To examine the clinical outcomes and costs associated with<jats:italic>Staphylococcus aureus<\/jats:italic>bacteremia among hemodialysis-dependent patients.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X0019840X_abs2\"><jats:title>Design:<\/jats:title><jats:p>Prospectively identified cohort study.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X0019840X_abs3\"><jats:title>Setting:<\/jats:title><jats:p>A tertiary-care university medical center in North Carolina.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X0019840X_abs4\"><jats:title>Patients:<\/jats:title><jats:p>Two hundred ten hemodialysis-dependent adults with end-stage renal disease hospitalized with<jats:italic>S. aureus<\/jats:italic>bacteremia.<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X0019840X_abs5\"><jats:title>Results:<\/jats:title><jats:p>The majority of the patients (117; 55.7%) underwent dialysis via tunneled catheters, and 29.5% (62) underwent dialysis via synthetic arteriovenous fistulas. Vascular access was the suspected source of bacteremia in 185 patients (88.1%). Complications occurred in 31.0% (65), and the overall 12-week mortality rate was 19.0% (40). The mean cost of treating<jats:italic>S. aureus<\/jats:italic>bacteremia, including readmissions and outpatient costs, was $24,034 per episode. The mean initial hospitalization cost was significantly greater for patients with complicated versus uncomplicated<jats:italic>S. aureus<\/jats:italic>bacteremia ($32,462 vs $17,011;<jats:italic>P<\/jats:italic>= .002).<\/jats:p><\/jats:sec><jats:sec id=\"S0899823X0019840X_abs6\"><jats:title>Conclusion:<\/jats:title><jats:p>Interventions to decrease the rate of S.<jats:italic>aureus<\/jats:italic>bacteremia are needed in this high-risk, hemodialysis-dependent population (<jats:italic>Infect Control Hosp Epidemiol<\/jats:italic>2005;26:534-539).<\/jats:p><\/jats:sec>","DOI":"10.1086\/502580","type":"journal-article","created":{"date-parts":[[2006,4,14]],"date-time":"2006-04-14T20:33:48Z","timestamp":1145046828000},"page":"534-539","source":"Crossref","is-referenced-by-count":124,"title":["Clinical Outcomes and Costs Due to<i>Staphylococcus aureus<\/i>Bacteremia Among Patients Receiving Long-Term Hemodialysis"],"prefix":"10.1017","volume":"26","author":[{"given":"John J.","family":"Engemann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00eblle Y.","family":"Friedman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shelby D.","family":"Reed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert I.","family":"Griffiths","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynda A.","family":"Szczech","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith S.","family":"Kaye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin E.","family":"Stryjewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Barth","family":"Reller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin A.","family":"Schulman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. Ralph","family":"Corey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Vance G.","family":"Fowler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2016,6,21]]},"reference":[{"key":"S0899823X0019840X_ref017","doi-asserted-by":"publisher","DOI":"10.1086\/501641"},{"key":"S0899823X0019840X_ref019","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198510000-00009"},{"key":"S0899823X0019840X_ref015","doi-asserted-by":"publisher","DOI":"10.1086\/314712"},{"key":"S0899823X0019840X_ref023","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(94)90143-0"},{"key":"S0899823X0019840X_ref032","doi-asserted-by":"crossref","first-page":"2753","DOI":"10.1681\/ASN.V12122753","article-title":"Forecast of the number of patients with end-stage renal disease in the United States to the year 2010","volume":"12","author":"Xue","year":"2001","journal-title":"J Am Soc Nephrol"},{"key":"S0899823X0019840X_ref020","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1984.00350150137033"},{"key":"S0899823X0019840X_ref009","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(85)80104-9"},{"key":"S0899823X0019840X_ref003","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199808203390806"},{"key":"S0899823X0019840X_ref006","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/20.1.16"},{"key":"S0899823X0019840X_ref001","doi-asserted-by":"publisher","DOI":"10.1093\/clind\/24.4.584"},{"key":"S0899823X0019840X_ref012","doi-asserted-by":"publisher","DOI":"10.1159\/000064279"},{"key":"S0899823X0019840X_ref005","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-4453(97)92395-1"},{"key":"S0899823X0019840X_ref025","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.320.7243.1197"},{"key":"S0899823X0019840X_ref007","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.17.2066"},{"key":"S0899823X0019840X_ref013","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1681\/ASN.V95869","article-title":"EPIBACDIAL: a multicenter prospective study of risk factors for bacteremia in chronic hemodialysis patients","volume":"9","author":"Hoen","year":"1998","journal-title":"J Am Soc Nephrol"},{"key":"S0899823X0019840X_ref014","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1998.00134.x"},{"key":"S0899823X0019840X_ref022","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-129-11_Part_1-199812010-00004"},{"key":"S0899823X0019840X_ref018","doi-asserted-by":"publisher","DOI":"10.3201\/eid0501.990102"},{"key":"S0899823X0019840X_ref010","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-127-4-199708150-00003"},{"key":"S0899823X0019840X_ref002","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/23.2.255"},{"key":"S0899823X0019840X_ref024","volume-title":"Bureau of Labor Statistics Data","year":"2004"},{"key":"S0899823X0019840X_ref016","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1128\/JCM.30.3.670-674.1992","article-title":"Recurrent Staphylococcus aureus bacteremia","volume":"30","author":"Hartstein","year":"1992","journal-title":"J Clin Microbiol"},{"key":"S0899823X0019840X_ref029","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa011297"},{"key":"S0899823X0019840X_ref030","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa003069"},{"key":"S0899823X0019840X_ref028","doi-asserted-by":"publisher","DOI":"10.1086\/320001"},{"key":"S0899823X0019840X_ref031","volume-title":"United States Renal Data System","year":"2004"},{"key":"S0899823X0019840X_ref011","doi-asserted-by":"publisher","DOI":"10.1159\/000187285"},{"key":"S0899823X0019840X_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(05)70170-7"},{"key":"S0899823X0019840X_ref004","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(91)90349-3"},{"key":"S0899823X0019840X_ref026","doi-asserted-by":"publisher","DOI":"10.1023\/A:1012597123667"},{"key":"S0899823X0019840X_ref027","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03540460066034"},{"key":"S0899823X0019840X_ref021","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199206000-00025"}],"container-title":["Infection Control &amp; Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0899823X0019840X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,25]],"date-time":"2021-07-25T17:13:48Z","timestamp":1627233228000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0899823X0019840X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,6]]}},"alternative-id":["S0899823X0019840X"],"URL":"https:\/\/doi.org\/10.1086\/502580","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,6]]}}}