{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T10:18:21Z","timestamp":1780568301302,"version":"3.54.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[1997,10,1]],"date-time":"1997-10-01T00:00:00Z","timestamp":875664000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,19]],"date-time":"2013-07-19T00:00:00Z","timestamp":1374192000000},"content-version":"vor","delay-in-days":5770,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The American Journal of Human Genetics"],"published-print":{"date-parts":[[1997,10]]},"DOI":"10.1086\/514883","type":"journal-article","created":{"date-parts":[[2007,12,4]],"date-time":"2007-12-04T19:38:45Z","timestamp":1196797125000},"page":"928-933","source":"Crossref","is-referenced-by-count":50,"title":["Hereditary Geniospasm: Linkage to Chromosome 9q13-q21 and Evidence for Genetic Heterogeneity"],"prefix":"10.1016","volume":"61","author":[{"given":"P.R.","family":"Jarman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.W.","family":"Wood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.T.","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.V.","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.P.","family":"Bhatia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.D.","family":"Marsden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.B.","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1086\/514883_bib1","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/j.1399-0004.1991.tb03074.x","article-title":"Trembling chin: a report of this inheritable dominant character in a four-generation Canadian family","volume":"40","author":"Alsager","year":"1991","journal-title":"Clin Genet"},{"key":"10.1086\/514883_bib2","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1006\/geno.1996.0013","article-title":"A gene for autosomal dominant paroxysmal choreoathetosis\/spasticity (CSE) maps to the vicinity of a potassium channel gene cluster on chromosome 1p, probably within 2 cM between D1S443 and D1S197","volume":"31","author":"Auburger","year":"1996","journal-title":"Genomics"},{"key":"10.1086\/514883_bib3","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1093\/brain\/117.4.805","article-title":"A study of hereditary essential tremor","volume":"117","author":"Bain","year":"1994","journal-title":"Brain"},{"key":"10.1086\/514883_bib4","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/BF00343994","article-title":"Erbliches Kinnzittern in einer westspanischen Familie","volume":"231","author":"Becker","year":"1982","journal-title":"Arch Psychiatr Nervenkr"},{"key":"10.1086\/514883_bib5","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/mds.870020103","article-title":"Essential tongue tremor","volume":"2","author":"Biary","year":"1987","journal-title":"Mov Disord"},{"key":"10.1086\/514883_bib6","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1038\/ng1094-136","article-title":"Episodic ataxia\/myokymia syndrome is associated with point mutations in the human potassium channel gene, KCNA1","volume":"8","author":"Browne","year":"1994","journal-title":"Nat Genet"},{"key":"10.1086\/514883_bib7","first-page":"252","article-title":"Faster sequential genetic linkage computations","volume":"53","author":"Cottingham","year":"1993","journal-title":"Am J Hum Genet"},{"key":"10.1086\/514883_bib8","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/mds.870080314","article-title":"Geniospasm: hereditary chin trembling","volume":"8","author":"Danek","year":"1993","journal-title":"Mov Disord"},{"key":"10.1086\/514883_bib9","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1038\/380152a0","article-title":"A comprehensive genetic map of the human genome based on 5,264 microsatellites","volume":"380","author":"Dib","year":"1996","journal-title":"Nature"},{"key":"10.1086\/514883_bib10","first-page":"140","article-title":"Paroxysmal dystonic choreoathetosis: tight linkage to chromosome 2q","volume":"59","author":"Fink","year":"1996","journal-title":"Am J Hum Genet"},{"key":"10.1086\/514883_bib11","first-page":"135","article-title":"A gene for familial paroxysmal dyskinesia (FPD1) maps to chromosome 2q","volume":"59","author":"Fouad","year":"1996","journal-title":"Am J Hum Genet"},{"key":"10.1086\/514883_bib12","first-page":"121","article-title":"Erbliches Kinnzittern in einer Tiroler Talschaft","volume":"29","author":"Ganner","year":"1935","journal-title":"Arch Rassenbiol"},{"key":"10.1086\/514883_bib13","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/oxfordjournals.jhered.a102839","article-title":"The inheritance of \u201cfacial spasm.\u201d","volume":"18","author":"Goldsmith","year":"1927","journal-title":"J Hered"},{"key":"10.1086\/514883_bib14","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1177\/088307389300800208","article-title":"Successful treatment of hereditary trembling chin with botulinum toxin","volume":"8","author":"Gordon","year":"1993","journal-title":"J Child Neurol"},{"key":"10.1086\/514883_bib15","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1542\/peds.19.3.453","article-title":"Trembling of the chin: an inheritable dominant character","volume":"19","author":"Grossman","year":"1957","journal-title":"Pediatrics"},{"key":"10.1086\/514883_bib16","doi-asserted-by":"crossref","unstructured":"Jarman PR, Davis MB, Hodgson SV, Marsden CD, Wood NW. Paroxysmal dystonic choreoathetosis: genetic linkage studies in a British family. Brain (in press)","DOI":"10.1093\/brain\/120.12.2125"},{"key":"10.1086\/514883_bib17","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1002\/mds.870060307","article-title":"Tremor and idiopathic dystonia","volume":"6","author":"Jedynak","year":"1991","journal-title":"Mov Disord"},{"key":"10.1086\/514883_bib18","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1111\/j.1469-8749.1971.tb08344.x","article-title":"Hereditary chin-trembling with nocturnal myoclonus and tongue-biting in dizygous twins","volume":"13","author":"Johnson","year":"1971","journal-title":"Dev Med Child Neurol"},{"key":"10.1086\/514883_bib19","first-page":"468","article-title":"The DYT1 gene on 9q34 is responsible for most cases of early limb-onset idiopathic torsion dystonia in non-Jews","volume":"55","author":"Kramer","year":"1994","journal-title":"Am J Hum Genet"},{"key":"10.1086\/514883_bib20","first-page":"460","article-title":"Easy calculations of LOD scores and genetic risks on small computers","volume":"36","author":"Lathrop","year":"1984","journal-title":"Am J Hum Genet"},{"key":"10.1086\/514883_bib21","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1136\/adc.43.228.249","article-title":"Hereditary quivering of the chin","volume":"43","author":"Laurance","year":"1968","journal-title":"Arch Dis Child"},{"key":"10.1086\/514883_bib22","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1093\/hmg\/5.10.1673","article-title":"Idiopathic torsion dystonia: assignment of a gene to chromosome 18p in a German family with adult onset, autosomal dominant inheritance and purely focal distribution","volume":"5","author":"Leube","year":"1996","journal-title":"Hum Mol Genet"},{"key":"10.1086\/514883_bib23","first-page":"47","article-title":"Ventisei casi de geniospasmo attraverso cinque generazioni: contributo clinico allo studio dell' eredit\u00e1 fisio-patologica","volume":"1","author":"Massaro","year":"1894","journal-title":"I Pisani (Palermo)"},{"key":"10.1086\/514883_bib24","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1016\/0896-6273(89)90188-8","article-title":"Human gene for torsion dystonia located on chromosome 9q32-q34","volume":"2","author":"Ozelius","year":"1989","journal-title":"Neuron"},{"key":"10.1086\/514883_bib25","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1046\/j.1469-1809.1997.6130183.x","article-title":"Report on the Fifth International Workshop on Chromosome 9","volume":"61","author":"Povey","year":"1997","journal-title":"Ann Hum Genet"},{"key":"10.1086\/514883_bib26","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/0092-8674(91)90374-8","article-title":"Identification of a mutation in the gene causing hyperkalemic periodic paralysis","volume":"67","author":"Ptacek","year":"1991","journal-title":"Cell"},{"key":"10.1086\/514883_bib27","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/0092-8674(94)90135-X","article-title":"Dihydropyridine receptor mutations cause hypokalemic periodic paralysis","volume":"77","author":"Ptacek","year":"1994","journal-title":"Cell"},{"key":"10.1086\/514883_bib28","first-page":"276","article-title":"Clinical and epidemiological features of essential tremor of the jaw","volume":"6","author":"Rapoport","year":"1991","journal-title":"Mov Disord"},{"key":"10.1086\/514883_bib29","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/ng0794-390","article-title":"Chromosome-specific microsatellite sets for fluorescence-based, semi-automated genome mapping","volume":"7","author":"Reed","year":"1994","journal-title":"Nat Genet"},{"key":"10.1086\/514883_bib30","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1002\/mds.870110626","article-title":"Hereditary geniospasm: two new families","volume":"11","author":"Soland","year":"1996","journal-title":"Mov Disord"},{"key":"10.1086\/514883_bib31","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1093\/biomet\/14.3-4.311","article-title":"Facial spasm inherited through four generations","volume":"14","author":"Stocks","year":"1922","journal-title":"Biometrika"},{"key":"10.1086\/514883_bib32","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/S0022-3476(58)80218-8","article-title":"Familial trembling of the chin","volume":"53","author":"Wadlington","year":"1958","journal-title":"J Pediatr"},{"key":"10.1086\/514883_bib33","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1002\/cne.902910409","article-title":"Musculotopic organization of the facial motor nucleus in Macaca fascicularis: a morphometric and retrograde tracing study with cholera toxin B-HRP","volume":"291","author":"Welt","year":"1990","journal-title":"J Comp Neurol"}],"container-title":["The American Journal of Human Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002929707642025?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0002929707642025?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T01:14:15Z","timestamp":1708391655000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0002929707642025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,10]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1997,10]]}},"alternative-id":["S0002929707642025"],"URL":"https:\/\/doi.org\/10.1086\/514883","relation":{},"ISSN":["0002-9297"],"issn-type":[{"value":"0002-9297","type":"print"}],"subject":[],"published":{"date-parts":[[1997,10]]}}}