{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T11:42:29Z","timestamp":1787830949528,"version":"build-2784847793"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect Control Hosp Epidemiol"],"published-print":{"date-parts":[[2007,5]]},"abstract":"<jats:sec id=\"S0195941700046233_abs1\">\n               <jats:title>Objective.<\/jats:title>\n               <jats:p>To investigate the prevalence, duration, and etiology of bacteremia following dental extractions performed after a single administration of Chlorhexidine mouthwash.<\/jats:p>\n            <\/jats:sec>\n            <jats:sec id=\"S0195941700046233_abs2\">\n               <jats:title>Design and Setting.<\/jats:title>\n               <jats:p>A randomized, controlled trial performed in a university hospital.<\/jats:p>\n            <\/jats:sec>\n            <jats:sec id=\"S0195941700046233_abs3\">\n               <jats:title>Methods.<\/jats:title>\n               <jats:p>A series of 106 patients with mental and behavioral disabilities who underwent dental extractions under general anesthesia were randomly assigned to a control group or Chlorhexidine group. The exclusion criteria applied were use of antibiotics in the previous 3 months, use of oral antiseptics, any type of congenital or acquired immunodeficiency, and disease that predisposes the patient to infections or bleeding. The Chlorhexidine group had 0.2% Chlorhexidine mouthwash administered for 30 seconds before any dental manipulation. Blood samples were collected at baseline, 30 seconds, 15 minutes, and 1 hour after the dental extractions. Subculture and further identification of the isolated bacteria were performed by conventional microbiological techniques.<\/jats:p>\n            <\/jats:sec>\n            <jats:sec id=\"S0195941700046233_abs4\">\n               <jats:title>Results.<\/jats:title>\n               <jats:p>The prevalence of bacteremia after dental extraction in the control and Chlorhexidine groups were 96% and 79%, respectively, at 30 seconds (<jats:italic>P<\/jats:italic> = .008), 64% and 30% at 15 minutes (<jats:italic>P<\/jats:italic> &amp;lt;.001), and 20% and 2% at 1 hour (<jats:italic>P<\/jats:italic> = .005). The most frequently identified bacteria were <jats:italic>Streptococcus<\/jats:italic> species in both the control and Chlorhexidine groups (64% and 68%, respectively), particularly viridans group streptococci.<\/jats:p>\n            <\/jats:sec>\n            <jats:sec id=\"S0195941700046233_abs5\">\n               <jats:title>Conclusion.<\/jats:title>\n               <jats:p>We recommend the routine use of a 0.2% Chlorhexidine mouthwash before dental extractions to reduce the risk of postextraction bacteremia.<\/jats:p>\n            <\/jats:sec>","DOI":"10.1086\/516663","type":"journal-article","created":{"date-parts":[[2007,4,19]],"date-time":"2007-04-19T17:46:39Z","timestamp":1177004799000},"page":"577-582","source":"Crossref","is-referenced-by-count":47,"title":["Effect of a Chlorhexidine Mouthwash on the Risk of Postextraction Bacteremia"],"prefix":"10.1017","volume":"28","author":[{"given":"I.","family":"Tom\u00e1s","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Limeres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Tom\u00e1s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Medina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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