{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T06:15:19Z","timestamp":1791180919121,"version":"4.1.0"},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T00:00:00Z","timestamp":1420156800000},"content-version":"unspecified","delay-in-days":2711,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2007,8]]},"abstract":"<jats:p>In a 30-month prospective study, we evaluated the efficacy of chlorine dioxide to control <jats:italic>Legionella<\/jats:italic> organisms in a water distribution system of a hospital with 364 patient beds and 74 skilled nursing beds. The number of hot water specimens positive for <jats:italic>Legionella<\/jats:italic> organisms decreased from 12 (60%) of 20 to 2 (10%) of 20. An extended time (18 months) was needed to achieve a significant reduction in the rate of <jats:italic>Legionella<\/jats:italic> positivity among hot water specimens. At the time of writing, no cases of hospital-acquired Legionnaires disease have been detected at the hospital since the chlorine dioxide system was installed in January 2003. Use of chlorine dioxide was safe, based on Environmental Protection Agency limits regarding maximum concentrations of chlorine dioxide and chlorite.<\/jats:p>","DOI":"10.1086\/518847","type":"journal-article","created":{"date-parts":[[2007,7,5]],"date-time":"2007-07-05T14:29:01Z","timestamp":1183645741000},"page":"1009-1012","source":"Crossref","is-referenced-by-count":34,"title":["Safety and Efficacy of Chlorine Dioxide for <i>Legionella<\/i> Control in a Hospital Water System"],"prefix":"10.1017","volume":"28","author":[{"given":"Zhe","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"McCann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet E.","family":"Stout","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Piesczynski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Hawks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radisav","family":"Vidic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor L.","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,1,2]]},"reference":[{"key":"S0195941700047184_ref003","volume-title":"Evaluation of chlorine dioxide in potable water systems for Legionella control in an acute care hospital environment","author":"Bova","year":"2004"},{"key":"S0195941700047184_ref004","first-page":"300","volume-title":"Test Method: Determination of Inorganic Anions in Drinking Water by Ion Chromatography","year":"1997"},{"key":"S0195941700047184_ref011","volume-title":"Control of Legionella in domestic water systems and potential energy savings resulting from the control of legionellae with chlorine dioxide","author":"Makin","year":"1998"},{"key":"S0195941700047184_ref010","first-page":"86","article-title":"Six years' experience with chlorine dioxide in control of Legionella pneumophila in potable water supply of Glasgow Royal Infirmary","volume":"28","author":"Hood","year":"2000","journal-title":"Am J Infect Control"},{"key":"S0195941700047184_ref006","doi-asserted-by":"publisher","DOI":"10.1086\/502251"},{"key":"S0195941700047184_ref007","unstructured":"Zhang Z , Stout JE , Vidic RD . The impact of temperature and TOC on chlorine dioxide decay in drinking water. Paper presented at: American Water Works Association Annual Conference and Exposition; June 11 -15, 2006; San Antonio, TX."},{"key":"S0195941700047184_ref001","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1002\/j.1551-8833.2004.tb10538.x","article-title":"Keeping Legionella out of water systems","volume":"96","author":"Sidari","year":"2004","journal-title":"J Am Water Works Assoc"},{"key":"S0195941700047184_ref002","doi-asserted-by":"publisher","DOI":"10.1086\/502254"},{"key":"S0195941700047184_ref005","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/j.1551-8833.1998.tb08503.x","article-title":"Legionella in water distribution systems","volume":"90","author":"Lin","year":"1998","journal-title":"J Am Water Works Assoc"},{"key":"S0195941700047184_ref009","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-6701(96)90058-4"},{"key":"S0195941700047184_ref008","unstructured":"Harris A , Rendell M . The elimination of Legionella in local hot and cold water systems using a novel chlorine dioxide technique. In: Program and abstracts of the 60th Annual International Water Conference; October 18-20, 1999; Pittsburgh, PA. Abstract IWC-99-18."}],"container-title":["Infection Control &amp; Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0195941700047184","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T21:48:52Z","timestamp":1556747332000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0195941700047184\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8]]},"references-count":11,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2007,8]]}},"alternative-id":["S0195941700047184"],"URL":"https:\/\/doi.org\/10.1086\/518847","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,8]]}}}