{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:48:24Z","timestamp":1762505304884},"reference-count":20,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T00:00:00Z","timestamp":1420156800000},"content-version":"unspecified","delay-in-days":2589,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2007,12]]},"abstract":"<jats:sec id=\"S0195941700026321_abs1\"><jats:title>Objective.<\/jats:title><jats:p>To compare the ability of 2 types of dressings to contain vaccinia virus after smallpox vaccination.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700026321_abs2\"><jats:title>Design.<\/jats:title><jats:p>Prospective, nonrandomized trial.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700026321_abs3\"><jats:title>Setting.<\/jats:title><jats:p>The smallpox vaccination clinic in a medium-sized military hospital.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700026321_abs4\"><jats:title>Participants.<\/jats:title><jats:p>Ninety-seven active-duty military members who received smallpox vaccination in accordance with US Department of Defense and Centers for Disease Control and Prevention guidelines.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700026321_abs5\"><jats:title>Methods.<\/jats:title><jats:p>The first 40 participants enrolled were instructed to cover their vaccination sites with a semipermeable membrane placed over a separate gauze pad, and the subsequent 57 participants were given a semipermeable membrane bonded to an absorbent pad. Swab samples of the external surface of the dressing were collected 7 and 21 days after vaccination. Real-time quantitative polymerase chain reaction was used to detect vaccinia DNA in the samples.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700026321_abs6\"><jats:title>Results.<\/jats:title><jats:p>The rate of vaccinia DNA detection was significantly higher for samples obtained from vaccinees who were using the separate gauze and semipermeable membrane, compared with the vacinees who were using the gauze-impregnated semipermeable membrane (22% vs 2.2%;<jats:italic>P<\/jats:italic>= .008; odds ratio, 12.3 [95% confidence interval, 1.4-567.4]).<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700026321_abs7\"><jats:title>Conclusion.<\/jats:title><jats:p>A gauze-impregnated semipermeable membrane more effectively reduced viral passage to the external surface of the dressing than did a semipermeable membrane placed over a separate gauze pad. Routine use of such dressings following smallpox vaccination might reduce the incidence of autoinoculation and secondary transmission.<\/jats:p><\/jats:sec>","DOI":"10.1086\/523277","type":"journal-article","created":{"date-parts":[[2007,12,5]],"date-time":"2007-12-05T10:59:57Z","timestamp":1196852397000},"page":"1339-1343","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of a Semipermeable Dressing Bonded to an Absorbent Pad and a Semipermeable Dressing Over a Separate Gauze Pad for Containment of Vaccinia Virus at the Vaccination Site"],"prefix":"10.1017","volume":"28","author":[{"given":"Michael R.","family":"Savona","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilfred P. Dela","family":"Cruz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer A.","family":"Thornton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick J.","family":"Danaher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,1,2]]},"reference":[{"key":"S0195941700026321_ref004","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra022500"},{"key":"S0195941700026321_ref018","unstructured":"Centers for Disease Control and Prevention. Guidelines and recommendations: Smallpox vaccination status and procedures\u2014guidelines for grantees using licensed undiluted Wyeth Dryvax vaccine. Available at: http:\/\/www.bt.cdc.gov\/agent\/smallpox\/vaccination\/pdf\/statusprocedure.pdf. Accessed July 3, 2007."},{"key":"S0195941700026321_ref008","unstructured":"Military Vaccine Agency. Smallpox vaccination safety summary. Available at: http:\/\/www.smallpox.mil\/event\/SPSafetySum.asp. Accessed July 3, 2007."},{"key":"S0195941700026321_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)91636-9"},{"key":"S0195941700026321_ref002","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1975.24.656"},{"key":"S0195941700026321_ref011","first-page":"1","article-title":"Vaccinia (smallpox) vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2001","volume":"50","author":"Rotz","year":"2001","journal-title":"MMWR Recomm Rep"},{"key":"S0195941700026321_ref015","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2003.026781"},{"key":"S0195941700026321_ref010","unstructured":"World Health Organization. Fact sheet on smallpox. Available at: http:\/\/www.who.int\/mediacentre\/factsheets\/smallpox\/en\/. Accessed July 3, 2007."},{"key":"S0195941700026321_ref014","doi-asserted-by":"publisher","DOI":"10.1086\/423967"},{"key":"S0195941700026321_ref007","doi-asserted-by":"publisher","DOI":"10.1007\/BF01313805"},{"key":"S0195941700026321_ref012","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/166.2.244"},{"key":"S0195941700026321_ref009","unstructured":"Smallpox vaccine, eczema vaccinatum\u2014USA. ProMED-Mail March 18, 2007: 20070318.0947. Available at: http:\/\/www.promedmail.org. Accessed July 3, 2007."},{"key":"S0195941700026321_ref006","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1128\/IAI.11.4.617-621.1975","article-title":"Response of camels to intradermal inoculation with smallpox and camelpox viruses","volume":"11","author":"Baxby","year":"1975","journal-title":"Infect Immun"},{"key":"S0195941700026321_ref016","volume-title":"Dryvax (smallpox vaccine dry, calf lymph type) [package insert]. Dried Smallpox vaccine","year":"2004"},{"key":"S0195941700026321_ref020","first-page":"103","article-title":"Secondary and tertiary transfer of vaccinia virus among U.S. military personnel\u2014United States and worldwide, 2002-2004","volume":"53","year":"2004","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"S0195941700026321_ref017","unstructured":"Department of Defense. Clinical policy for the Department of Defense smallpox vaccination program (SVP). Available at: http:\/\/www.smallpox.mil\/documents\/219SPclinicalpolicy.pdf. Accessed July 3, 2007."},{"key":"S0195941700026321_ref001","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1970.03170160031005"},{"key":"S0195941700026321_ref005","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.16.1898"},{"key":"S0195941700026321_ref019","first-page":"175","volume-title":"Rapid detection of orthopoxvirus DNA by Light Cycler PCR with Taqman primer probe set","author":"Xia","year":"2003"},{"key":"S0195941700026321_ref013","doi-asserted-by":"publisher","DOI":"10.1086\/381205"}],"container-title":["Infection Control &amp; Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0195941700026321","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,29]],"date-time":"2020-04-29T04:33:49Z","timestamp":1588134829000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0195941700026321\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12]]},"references-count":20,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["S0195941700026321"],"URL":"https:\/\/doi.org\/10.1086\/523277","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,12]]}}}