{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T10:18:58Z","timestamp":1789726738372,"version":"4.0.1"},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T00:00:00Z","timestamp":1420156800000},"content-version":"unspecified","delay-in-days":2102,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2009,4]]},"abstract":"<jats:p>To evaluate the utility of the QuantiFERON-TB Gold assay for monitoring latent tuberculosis treatment efficacy, the assay was performed serially for healthcare workers receiving isoniazid therapy. After 9 months of isoniazid therapy, all of these healthcare workers remained QuantiFERON-TB Gold positive, and cellular proliferation assays revealed persistently strong purified protein derivative responses. These results do not support the use of the QuantiFERON-TB Gold assay to monitor therapy.<\/jats:p>","DOI":"10.1086\/596606","type":"journal-article","created":{"date-parts":[[2009,2,23]],"date-time":"2009-02-23T23:11:34Z","timestamp":1235430694000},"page":"392-395","source":"Crossref","is-referenced-by-count":24,"title":["Evaluation of the Effect of Treatment of Latent Tuberculosis Infection on QuantiFERON-TB Gold Assay Results"],"prefix":"10.1017","volume":"30","author":[{"given":"Nira R.","family":"Pollock","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suely S.","family":"Kashino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle R.","family":"Napolitano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Sloutsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swati","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmine","family":"Guillet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Nardell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Campos-Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,1,2]]},"reference":[{"key":"S0195941700036614_ref008","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200511-1783OC"},{"key":"S0195941700036614_ref005","unstructured":"Public Health Agency of Canada. International tuberculosis incidence rates. March 31, 2008. Available at: http:\/\/www.phac-aspc.gc.ca\/tbpc-latb\/itir_e.html. Accessed September 1, 2008."},{"key":"S0195941700036614_ref002","first-page":"1","article-title":"Guidelines for preventing the transmission of Mycobacterium tuberculosis in health-care settings, 2005","volume":"54","author":"Jensen","year":"2005","journal-title":"MMWR Recomm Rep"},{"key":"S0195941700036614_ref010","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2008.01244.x"},{"key":"S0195941700036614_ref003","unstructured":"QuantiFERON-TB Gold [package insert]. Document no. 05980000C. Victoria, Australia: Cellestis; 2006."},{"key":"S0195941700036614_ref006","doi-asserted-by":"publisher","DOI":"10.1086\/499311"},{"key":"S0195941700036614_ref011","doi-asserted-by":"publisher","DOI":"10.1186\/1465-9921-8-5"},{"key":"S0195941700036614_ref007","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200608-1109OC"},{"key":"S0195941700036614_ref001","first-page":"49","article-title":"Guidelines for using the QuantiFERON-TB Gold test for detecting Mycobacterium tuberculosis infection, United States","volume":"54","author":"Mazurek","year":"2005","journal-title":"MMWR Recomm Rep"},{"key":"S0195941700036614_ref004","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00010-08"},{"key":"S0195941700036614_ref009","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6673-1-7"}],"container-title":["Infection Control &amp; Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0195941700036614","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T19:25:04Z","timestamp":1556652304000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0195941700036614\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,4]]}},"alternative-id":["S0195941700036614"],"URL":"https:\/\/doi.org\/10.1086\/596606","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4]]}}}