{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T06:01:31Z","timestamp":1775800891789,"version":"3.50.1"},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T00:00:00Z","timestamp":1420156800000},"content-version":"unspecified","delay-in-days":1949,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:sec id=\"S0195941700037450_abs1\"><jats:title>Background.<\/jats:title><jats:p>Infection-control interventions are needed to minimize transmission of influenza-like illness (ILI) and other infections in settings where children are in close proximity.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700037450_abs2\"><jats:title>Setting.<\/jats:title><jats:p>A 240-children Thai kindergarten.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700037450_abs3\"><jats:title>Methods.<\/jats:title><jats:p>Three-year, quasi-experimental study was conducted to assess the association between the use of a bundle of 4 infection control interventions and the incidence of ILI, diarrheal illnesses, and hand-foot-mouth infections among preschool children. The numbers of incident infections were calculated for the preintervention year (period 1), the immediate postintervention year (period 2), and the sustained postintervention year (period 3).<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700037450_abs4\"><jats:title>Results.<\/jats:title><jats:p>The monthly incidence of ILI in period 1 (mean, 124 episodes per month) was 25.8 cases per 1,000 child-days; in period 2, it was 10.1 cases per 1,000 child-days (a reduction of 60.8%; P = .008); and in period 3, it was 8.2 cases per 1,000 child-days (a further reduction of 19%;<jats:italic>P<\/jats:italic>= .002). The monthly incidence of diarrheal illnesses in period 1 was 14 cases per 1,000 child-days; in period 2, it was 4 cases per 1,000 child-days (<jats:italic>P<\/jats:italic>= .01); and in period 3, it was 3 cases per 1,000 child-days (<jats:italic>P<\/jats:italic>= .007). The yearly incidence of hand-foot-mouth infection in period 1 was 10 cases per 1,000 child-days; in period 2, it was 1 case per 1,000 child-days (<jats:italic>P<\/jats:italic>= .01); and in period 3, it was 0.5 cases per 1,000 child-days per year (<jats:italic>P<\/jats:italic>= .007).<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700037450_abs5\"><jats:title>Conclusion.<\/jats:title><jats:p>Use of the infection control intervention bundle was associated with reduced incidence of ILI at the Thai preschool.<\/jats:p><\/jats:sec>","DOI":"10.1086\/599773","type":"journal-article","created":{"date-parts":[[2009,7,17]],"date-time":"2009-07-17T20:16:59Z","timestamp":1247861819000},"page":"817-822","source":"Crossref","is-referenced-by-count":11,"title":["Intervention with an Infection Control Bundle to Reduce Transmission of Influenza-Like Illnesses in a Thai Preschool"],"prefix":"10.1017","volume":"30","author":[{"given":"Anucha","family":"Apisarnthanarak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piyaporn","family":"Apisarnthanarak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boonsri","family":"Cheevakumjorn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda M.","family":"Mundy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,1,2]]},"reference":[{"key":"S0195941700037450_ref012","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2597"},{"key":"S0195941700037450_ref015","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-0199"},{"key":"S0195941700037450_ref021","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2006.10.019"},{"key":"S0195941700037450_ref008","first-page":"182","article-title":"Influenza in Thailand: a case study for middle income countries","volume":"23","author":"Simmerman","year":"2004","journal-title":"Vacane"},{"key":"S0195941700037450_ref010","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-1734"},{"key":"S0195941700037450_ref018","doi-asserted-by":"publisher","DOI":"10.1086\/587495"},{"key":"S0195941700037450_ref005","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/12.Supplement_8.S923"},{"key":"S0195941700037450_ref004","first-page":"652","article-title":"Prevalence of rotavirus, adenovirus and astrovirus infection in young children with gastroenteritis in Gaborone, Botswana","volume":"80","author":"Basu","year":"2003","journal-title":"East Afr Med J"},{"key":"S0195941700037450_ref011","doi-asserted-by":"publisher","DOI":"10.1086\/529211"},{"key":"S0195941700037450_ref001","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1542\/peds.79.1.55","article-title":"Childhood upper respiratory tract infections: to what degree is incidence affected by daycare attendance?","volume":"79","author":"Fleming","year":"1987","journal-title":"Pediatrics"},{"key":"S0195941700037450_ref019","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1446.2006.00607.x"},{"key":"S0195941700037450_ref020","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2008.09.017"},{"key":"S0195941700037450_ref013","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa055414"},{"key":"S0195941700037450_ref006","first-page":"88","article-title":"Hand, foot and mouth disease: University Malaya medical center experience","volume":"57","author":"Hooi","year":"2002","journal-title":"Med J Malaysia"},{"key":"S0195941700037450_ref002","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(88)80164-1"},{"key":"S0195941700037450_ref007","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0002101"},{"key":"S0195941700037450_ref014","first-page":"733","article-title":"Assessment of the efficacy and effectiveness of influenza vaccines in healthy children: systematic review","volume":"365","author":"Jefferson","year":"2005","journal-title":"Lancet"},{"key":"S0195941700037450_ref017","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2007.11.013"},{"key":"S0195941700037450_ref009","first-page":"CD006207","article-title":"Interventions for the interruption or reduction of the spread of respiratory viruses","volume":"4","author":"Jefferson","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"S0195941700037450_ref003","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1542\/peds.57.2.191","article-title":"Respiratory illness in preschool children with different forms of day care","volume":"57","author":"Strangert","year":"1976","journal-title":"Pediatrics"},{"key":"S0195941700037450_ref016","first-page":"88","article-title":"Non-pharmaceutical interventions for pandemic influenza, national and community measures","volume":"12","author":"Bell","year":"2006","journal-title":"Emerg Infect Dis"}],"container-title":["Infection Control &amp; 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