{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:18:25Z","timestamp":1761488305209},"reference-count":29,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T00:00:00Z","timestamp":1420156800000},"content-version":"unspecified","delay-in-days":1919,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:sec id=\"S019594170003784X_abs1\"><jats:title>Objectives.<\/jats:title><jats:p>Medical and nursing students (hereafter referred to as \u201chealthcare students\u201d) are at risk of contracting and transmitting infectious diseases in a hospital Setting. The aim of our study was to evaluate the vaccination history of healthcare students and their serologic immunity against vaccine-preventable diseases.<\/jats:p><\/jats:sec><jats:sec id=\"S019594170003784X_abs2\"><jats:title>Design.<\/jats:title><jats:p>Prospective cohort study.<\/jats:p><\/jats:sec><jats:sec id=\"S019594170003784X_abs3\"><jats:title>Setting.<\/jats:title><jats:p>A tertiary care children's hospital in Athens, Greece, which is affiliated with the University of Athens.<\/jats:p><\/jats:sec><jats:sec id=\"S019594170003784X_abs4\"><jats:title>Methods.<\/jats:title><jats:p>Healthcare students were recruited during April through November 2007. The information obtained from these students during personal interviews included demographics and whether there was a history of varicella, measles, mumps, rubella, and\/or hepatitis A or B virus infection. Vaccination history and documentation of disease were abstracted from available medical records. Serum antibodies against the above-mentioned viral agents were determined by use of an enzyme-linked immunosorbent assay. Seronegative students and those with immunization gaps were referred to local vaccination clinics, and compliance was assessed 3 months later.<\/jats:p><\/jats:sec><jats:sec id=\"S019594170003784X_abs5\"><jats:title>Results.<\/jats:title><jats:p>A total of 187 healthcare students were recruited, 131 (70.1%) of whom provided complete documentation of vaccination history. Adequate immunity against diphtheria and tetanus was documented for 55 (37.2%) and 73 (49.3%) of the 148 participants, respectively, whereas age-appropriate vaccination against pertussis, diphtheria, tetanus, and poliomyelitis was noted for 138 (93.2%), 147 (99.3%), 147 (99.3%), and 147 (99.3%) healthcare students, respectively. Of 185 healthcare students, 171 (92.4%) were immune to varicella. Of 182 healthcare students, 179 (98.4%) were immune to measles, 163 (89.6%) were immune to mumps, and 176 (96.7%) were immune to rubella. Of 179 healthcare students, 151 (84.4%) were immune to hepatitis B virus. Of 178 healthcare students, 26 (14.6%) were immune to hepatitis A virus. Antibodies (10 IU\/L or higher) to hepatitis B surface antigen were detected for 151 (84.4%) of 179 healthcare students, and antibodies (10 IU\/L or higher) to hepatitis A virus were detected for 26 (14.6%) of 178 healthcare students. Fewer than 30% of participants were in full compliance with recommended vaccinations.<\/jats:p><\/jats:sec><jats:sec id=\"S019594170003784X_abs6\"><jats:title>Conclusions.<\/jats:title><jats:p>We have determined that there is a certain proportion of healthcare students who are susceptible to certain vaccine-preventable diseases. The development of an appropriate vaccination strategy is required to decrease the risk of transmission in a hospital setting.<\/jats:p><\/jats:sec>","DOI":"10.1086\/605923","type":"journal-article","created":{"date-parts":[[2009,8,26]],"date-time":"2009-08-26T18:59:12Z","timestamp":1251313152000},"page":"1006-1011","source":"Crossref","is-referenced-by-count":16,"title":["Medical and Nursing Students with Suboptimal Protective Immunity against Vaccine-Preventable Diseases"],"prefix":"10.1017","volume":"30","author":[{"given":"Ioanna D.","family":"Pavlopoulou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George L.","family":"Daikos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Tzivaras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelos","family":"Bozas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Kosmidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constantinos","family":"Tsournakas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Theodoridou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,1,2]]},"reference":[{"key":"S019594170003784X_ref012","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-113-8-628"},{"key":"S019594170003784X_ref022","doi-asserted-by":"publisher","DOI":"10.1086\/502910"},{"key":"S019594170003784X_ref019","first-page":"18","article-title":"Susceptibility to poliomyelitis, measles, mumps and rubella in university students","volume":"77","author":"Schoub","year":"1990","journal-title":"S Afr Med J"},{"key":"S019594170003784X_ref006","first-page":"1511","volume-title":"Vaccines","author":"Weber","year":"2004"},{"key":"S019594170003784X_ref014","doi-asserted-by":"publisher","DOI":"10.1078\/1438-4639-00333"},{"key":"S019594170003784X_ref027","first-page":"E060223.2","article-title":"Current measles outbreak in Greece","volume":"11","author":"Georgakopoulou","year":"2006","journal-title":"Euro Surv\u00e4ll"},{"key":"S019594170003784X_ref001","first-page":"45","volume-title":"Bennett and Brachman's hospital infections","author":"Beltrami","year":"2007"},{"key":"S019594170003784X_ref016","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kqg077"},{"key":"S019594170003784X_ref013","first-page":"957","article-title":"Immunization policies in Canadian medical schools","volume":"151","author":"Rowan","year":"1994","journal-title":"CMAJ"},{"key":"S019594170003784X_ref020","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1993.00410160081007"},{"key":"S019594170003784X_ref023","doi-asserted-by":"crossref","first-page":"484","DOI":"10.5694\/j.1326-5377.2008.tb02139.x","article-title":"Vaccination and screening of medical students: results of a student health initiative","volume":"189","author":"Torda","year":"2008","journal-title":"Med J Aust"},{"key":"S019594170003784X_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)80725-5"},{"key":"S019594170003784X_ref005","first-page":"1","article-title":"Prevention of varicella. 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