{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T03:23:51Z","timestamp":1781061831835,"version":"3.54.1"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T00:00:00Z","timestamp":1420156800000},"content-version":"unspecified","delay-in-days":7247,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[1995,3]]},"abstract":"Abstract<\/jats:title>\n \n Objective:<\/jats:title>\n To evaluate the efficacy of Centers for Disease Control and Prevention (CDC)-recommended infection control measures implemented in response to an outbreak of multidrug-resistant (MDR) tuberculosis (TB).<\/jats:p>\n <\/jats:sec>\n \n Design:<\/jats:title>\n Retrospective cohort studies of acquired immunodeficiency syndrome (AIDS) patients and healthcare workers. The study period (January 1989 through September 1992) was divided into period I, before changes in infection control; period II, after aggressive use of administrative controls (eg, rapid placement of TB patients or suspected TB patients in single-patient rooms); and period III, while engineering changes were made (eg, improving ventilation in TB isolation rooms).<\/jats:p>\n <\/jats:sec>\n \n Setting:<\/jats:title>\n A New York City hospital that was the site of one of the first reported outbreaks of MDR-TB among AIDS patients in the United States.<\/jats:p>\n <\/jats:sec>\n \n Participants:<\/jats:title>\n All AIDS patients admitted during periods I and II. Healthcare workers on nine inpatient units with TB patients and six without TB patients.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The epidemic (38 patients) waned during period II and only one MDR-TB patient presented during period III. The MDR-TB attack rate among AIDS patients hospitalized on the same ward on the same days as an infectious MDR-TB patient was 8.8% (19 of 216) during period I, decreasing to 2.6% (5 of 193;\n P=<\/jats:italic>\n 0.01) during period II. In a small group of healthcare workers with tuberculin skin test data, conversions during periods II through III were higher on wards with than without TB patients (5 of 29 versus 0 of 15;\n P=<\/jats:italic>\n 0.15), although the difference was not statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n Transmission of MDR-TB among AIDS patients decreased markedly after enforcement of readily implementable administrative measures, ending the outbreak. However, tuberculin skin-test conversions among healthcare workers may not have been prevented by these measures. CDC guidelines for prevention of nosocomial transmission of TB should be implemented fully at all US hospitals.<\/jats:p>\n <\/jats:sec>","DOI":"10.1086\/647075","type":"journal-article","created":{"date-parts":[[2009,9,16]],"date-time":"2009-09-16T13:57:09Z","timestamp":1253109429000},"page":"141-147","source":"Crossref","is-referenced-by-count":28,"title":["Evaluation of Infection Control Measures in Preventing the Nosocomial Transmission of Multidrug-Resistant Mycobacterium tuberculosis in a New York City Hospital"],"prefix":"10.1017","volume":"16","author":[{"given":"Leonardo A.","family":"Stroud","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome I.","family":"Tokars","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael H.","family":"Grieco","sequence":"additional","affiliation":[{"name":"St. Luke's-Roosevelt Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack T.","family":"Crawford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David H.","family":"Culver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian R.","family":"Edlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilia M.","family":"Sordillo","sequence":"additional","affiliation":[{"name":"St. Luke's-Roosevelt Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles L.","family":"Woodley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Ellen","family":"Gilligan","sequence":"additional","affiliation":[{"name":"St. Luke's-Roosevelt Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Schneider","sequence":"additional","affiliation":[{"name":"St. Luke's-Roosevelt Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Williams","sequence":"additional","affiliation":[{"name":"St. Luke's-Roosevelt Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William R.","family":"Jarvis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,1,2]]},"container-title":["Infection Control & Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S019594170000727X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T05:48:33Z","timestamp":1762494513000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S019594170000727X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,3]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,3]]}},"alternative-id":["S019594170000727X"],"URL":"https:\/\/doi.org\/10.1086\/647075","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,3]]}}}