{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T05:30:02Z","timestamp":1786426202553,"version":"build-2736575974"},"reference-count":20,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"unspecified","delay-in-days":10991,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[1996,7]]},"abstract":"Abstract<\/jats:title>\n \n Objective:<\/jats:bold>\n To implement and evaluate an algorithm designed to assist in the consistent placement of patients with suspected pulmonary tuberculosis into negative-pressure isolation rooms (NPIRs).\n <\/jats:p>\n \n Design:<\/jats:bold>\n A standard algorithm was designed for the appropriate room placement of patients with suspected pulmonary tuberculosis using clinical, radiographic, and laboratory criteria and reported risk factors. A case-patient was defined as an inpatient who had at least one\n Mycobacterium tuberculosis<\/jats:italic>\n culture-positive respiratory specimen from January 1, 1993, through December 31, 1994. Demographic, clinical, laboratory, case contact, and isolation and room placement data were collected prospectively on all case-patients.\n <\/jats:p>\n \n Setting:<\/jats:bold>\n A 900-bed university teaching and referral center.\n <\/jats:p>\n \n Results:<\/jats:bold>\n During 1993 and 1994, 69 patients were evaluated for possible pulmonary tuberculosis, and 31 case-patients were identified. Of the 31 case-patients, 26 (84%) were placed on respiratory isolation in NPIRs, including 19 (61%) who were isolated within 24 hours of admission (1993, 14 of 20 [70%]; 1994, 5 of 11 [45%]). Seven case-patients (23%) were isolated in NPIRs following delays that ranged from 2 to 31 days (median, 9 days), and five case-patients (16%) never were isolated during admissions of from 3 to 28 days (median, 4 days). These 12 case-patients contributed a total of 136 patient-exposure days during their hospitalizations. Misclassification of patient risk status by user error delayed isolation of five (42%) of the 12 improperly isolated case-patients.\n <\/jats:p>\n \n Conclusions:<\/jats:bold>\n The use of an algorithm incorporating radiographic, laboratory, and clinical criteria and reported risk factors may assist in the rapid isolation of patients with suspected pulmonary tuberculosis.\n <\/jats:p>","DOI":"10.1086\/647331","type":"journal-article","created":{"date-parts":[[2009,9,9]],"date-time":"2009-09-09T16:30:08Z","timestamp":1252513808000},"page":"412-418","source":"Crossref","is-referenced-by-count":8,"title":["Implementation and Evaluation of an Algorithm for Isolation of Patients With Suspected Pulmonary Tuberculosis"],"prefix":"10.1017","volume":"17","author":[{"given":"Clare F.","family":"Pegues","sequence":"first","affiliation":[{"name":"Massachusetts General Hospital"},{"name":"Massachusetts General Hospital"},{"name":"Massachusetts General Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas C.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Pegues","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital"},{"name":"Massachusetts General Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen","family":"Spencer","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyrus C.","family":"Hopkins","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital"},{"name":"Massachusetts General 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