{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T20:40:15Z","timestamp":1775508015305,"version":"3.50.1"},"reference-count":26,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T00:00:00Z","timestamp":1420156800000},"content-version":"unspecified","delay-in-days":1431,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:sec id=\"S0195941700039849_abs1\"><jats:title>Objective.<\/jats:title><jats:p>To establish whether continuous subglottic suctioning (CSS) could be cost-effective.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700039849_abs2\"><jats:title>Design.<\/jats:title><jats:p>Cost-benefit analysis, based on a hypothetical replacement of conventional ventilation (CV) with CSS.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700039849_abs3\"><jats:title>Setting.<\/jats:title><jats:p>A surgical intensive care unit (SICU) of a tertiary care university hospital in France.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700039849_abs4\"><jats:title>Patients.<\/jats:title><jats:p>All consecutive patients receiving ventilation in the SICU in 2006.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700039849_abs5\"><jats:title>Methods.<\/jats:title><jats:p>Efficacy data for CSS were obtained from the literature and applied to the SICU of our hospital. Costs for CV and CSS were provided by the hospital pharmacy; costs for ventilator-associated pneumonia (VAP) were obtained from the literature. The cost per averted VAP episode was calculated, and a sensitivity analysis was performed on VAP incidence and on the number of tubes required for each patient.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700039849_abs6\"><jats:title>Results.<\/jats:title><jats:p>At our SICU in 2006, 416 patients received mechanical ventilation for 3,487 ventilation-days, and 32 VAP episodes were observed (7.9 episodes per 100 ventilated patients; incidence density, 9.2 episodes per 10,000 ventilation-days). Based on the hypothesis of a 29% reduction in the risk of VAP with CSS than CV, 9 VAP episodes could have been averted. The additional cost of CSS for 2006 was estimated to be \u20ac10,585.34. The cost per averted VAP episode was \u20ac1,176.15. Assuming a VAP cost of \u20ac4,387, a total of 3 averted VAP episodes would neutralize the additional cost. For a low VAP incidence of 6.6%, the cost per averted VAP would be \u20ac1,323. If each patient required 2 tubes during ventilation, the cost would be \u20ac1,383.69 per averted VAP episode.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700039849_abs7\"><jats:title>Conclusion.<\/jats:title><jats:p>Replacement of CV with CSS was cost-effective even when assuming the most pessimistic scenario of VAP incidence and costs.<\/jats:p><\/jats:sec>","DOI":"10.1086\/657943","type":"journal-article","created":{"date-parts":[[2011,1,19]],"date-time":"2011-01-19T21:01:02Z","timestamp":1295470862000},"page":"131-135","source":"Crossref","is-referenced-by-count":17,"title":["Is Continuous Subglottic Suctioning Cost-Effective for the Prevention of Ventilator-Associated Pneumonia?"],"prefix":"10.1017","volume":"32","author":[{"given":"Corinne","family":"Hallais","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00e9ronique","family":"Merle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre-Gildas","family":"Guitard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Moreau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Val\u00e9rie","family":"Josset","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denis","family":"Thillard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Haghighat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benoit","family":"Veber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Czernichow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,1,2]]},"reference":[{"key":"S0195941700039849_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(93)90060-3"},{"key":"S0195941700039849_ref020","doi-asserted-by":"publisher","DOI":"10.1016\/S1553-7250(05)31031-2"},{"key":"S0195941700039849_ref026","doi-asserted-by":"publisher","DOI":"10.1097\/01.anes.0000282083.83319.5f"},{"key":"S0195941700039849_ref016","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.3.858"},{"key":"S0195941700039849_ref024","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000181731.53912.D9"},{"key":"S0195941700039849_ref019","doi-asserted-by":"publisher","DOI":"10.1016\/S1553-7250(07)33026-2"},{"key":"S0195941700039849_ref011","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2004.07.051"},{"key":"S0195941700039849_ref013","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-122-3-199502010-00004"},{"key":"S0195941700039849_ref009","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1H678"},{"key":"S0195941700039849_ref021","unstructured":"RAISIN. 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