{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T10:45:26Z","timestamp":1778841926729,"version":"3.51.4"},"reference-count":35,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T00:00:00Z","timestamp":1420156800000},"content-version":"unspecified","delay-in-days":1219,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:sec id=\"S0195941700050232_abs1\"><jats:title>Objective.<\/jats:title><jats:p>To assess the prevalence of and risk factors for carbapenem-resistant <jats:italic>Klebsiella pneumoniae<\/jats:italic> (CRKP) carriage among patients in post-acute-care facilities (PACFs) in Israel.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700050232_abs2\"><jats:title>Design, Setting, and Patients.<\/jats:title><jats:p>A cross-sectional prevalence survey was conducted in 12 PACFs. Rectal swab samples were obtained from 1,144 patients in 33 wards. Risk factors for CRKP carriage were assessed among the cohort. Next, a nested, matched case-control study was conducted to define individual risk factors for colonization. Finally, the cohort of patients with a history of CRKP carriage was characterized to determine risk factors for continuous carriage.<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700050232_abs3\"><jats:title>Results.<\/jats:title><jats:p>The prevalence of rectal carriage of CRKP among 1,004 patients without a history of CRKP carriage was 12.0%. Independent risk factors for CRKP carriage were prolonged length of stay (odds ratio [OR], 1.001; <jats:italic>P<\/jats:italic> &lt; .001), sharing a room with a known carrier (OR, 3.09; <jats:italic>P<\/jats:italic> = .02), and increased prevalence of known carriers on the ward (OR, 1.02; <jats:italic>P<\/jats:italic> = .013). A policy of screening for carriage on admission was protective (OR, 0.41; <jats:italic>P<\/jats:italic> = .03). Risk factors identified in the nested case-control study were antibiotic exposure during the prior 3 months (OR, 1.66; <jats:italic>P<\/jats:italic> = .03) and colonization with other resistant pathogens (OR, 1.64; <jats:italic>P<\/jats:italic> = .03). Among 140 patients with a history of CRKP carriage, 47% were colonized. Independent risk factors for continued CRKP carriage were antibiotic exposure during the prior 3 months (OR, 3.05; <jats:italic>P<\/jats:italic> = .04), receipt of amoxicillin-clavulanate (OR, 4.18; <jats:italic>P<\/jats:italic> = .007), and screening within 90 days of the first culture growing CRKP (OR, 2.9; <jats:italic>P<\/jats:italic> = .012).<\/jats:p><\/jats:sec><jats:sec id=\"S0195941700050232_abs4\"><jats:title>Conclusions.<\/jats:title><jats:p>We found a large reservoir of CRKP in PACFs. Infection-control polices and antibiotic exposure were associated with patient colonization.<\/jats:p><\/jats:sec>","DOI":"10.1086\/661279","type":"journal-article","created":{"date-parts":[[2011,8,9]],"date-time":"2011-08-09T15:57:24Z","timestamp":1312905444000},"page":"845-853","source":"Crossref","is-referenced-by-count":85,"title":["Carbapenem-Resistant <i>Klebsiella pneumoniae<\/i> in Post-Acute-Care Facilities in Israel"],"prefix":"10.1017","volume":"32","author":[{"given":"Debby","family":"Ben-David","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samira","family":"Masarwa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiri","family":"Navon-Venezia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hagit","family":"Mishali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilan","family":"Fridental","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bina","family":"Rubinovitch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gill","family":"Smollan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yehuda","family":"Carmeli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchell 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