{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:19:12Z","timestamp":1792811952960,"version":"4.5.0"},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T00:00:00Z","timestamp":1420156800000},"content-version":"unspecified","delay-in-days":945,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:sec id=\"S019594170003099X_abs1\"><jats:title>Background.<\/jats:title><jats:p>Viral respiratory pathogens cause outbreaks in pediatric long-term care facilities (LTCFs), but few studies have used viral diagnostic testing to identify the causative pathogens. We describe the use of such testing during a prolonged period of respiratory illness and elucidate the epidemiology of human metapneumovirus (hMPV) at our LTCF.<\/jats:p><\/jats:sec><jats:sec id=\"S019594170003099X_abs2\"><jats:title>Design.<\/jats:title><jats:p>Retrospective study of influenza-like illness (ILI).<\/jats:p><\/jats:sec><jats:sec id=\"S019594170003099X_abs3\"><jats:title>Setting.<\/jats:title><jats:p>A 136-bed pediatric LTCF from January 1 through April 30, 2010.<\/jats:p><\/jats:sec><jats:sec id=\"S019594170003099X_abs4\"><jats:title>Methods.<\/jats:title><jats:p>The ILI case definition included fever, cough, change in oropharyngeal secretions, increase in oxygen requirement, and\/or wheezing.<\/jats:p><\/jats:sec><jats:sec id=\"S019594170003099X_abs5\"><jats:title>Results.<\/jats:title><jats:p>During the study period, 69 episodes of ILI occurred in 61 (41%) of 150 residents. A viral pathogen was detected in 27 (39%) of the episodes, including respiratory syncytial virus (RSV) (<jats:italic>n<\/jats:italic> = 3), influenza A virus (not typed; <jats:italic>n<\/jats:italic> = 2), parainfluenza virus (<jats:italic>n<\/jats:italic> = 2), adenovirus (<jats:italic>n<\/jats:italic> = 1), and hMPV (<jats:italic>n<\/jats:italic> = 19). Twenty-seven of the residents with ILI (44%) required transfer to acute care hospitals (mean length of hospitalization, 12 days; range, 3\u201347 days). Residents with tracheostomies were more likely to have ILI (adjusted odds ratio [OR], 3.99 [95% confidence interval {CI}, 1.87\u20138.53]; <jats:italic>P<\/jats:italic> = .0004). The mortality rate for residents with ILI was 1.6%. Residents with hMPV were younger (<jats:italic>P<\/jats:italic> = .03), more likely to be transferred to an acute care facility (OR, 3.73 [95% CI, 1.17\u201311.95]; <jats:italic>P<\/jats:italic> = .02), and less likely to have a tracheostomy (adjusted OR, 0.19 [95% CI, 0.047\u20130.757]; <jats:italic>P<\/jats:italic> = .02).<\/jats:p><\/jats:sec><jats:sec id=\"S019594170003099X_abs6\"><jats:title>Discussion.<\/jats:title><jats:p>Diverse pathogens, most notably hMPV, caused ILI in our pediatric LTCF during a prolonged period of time. Viral testing was helpful in characterizing the epidemiology of ILI in this population.<\/jats:p><\/jats:sec>","DOI":"10.1086\/665727","type":"journal-article","created":{"date-parts":[[2012,5,4]],"date-time":"2012-05-04T18:50:24Z","timestamp":1336157424000},"page":"545-550","source":"Crossref","is-referenced-by-count":22,"title":["Epidemiology of Human Metapneumovirus in a Pediatric Long-Term Care Facility"],"prefix":"10.1017","volume":"33","author":[{"given":"Natalie","family":"Neu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Plaskett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon","family":"Hutcheon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen L.","family":"Southwick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Saiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,1,2]]},"reference":[{"key":"S019594170003099X_ref002","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa025472"},{"key":"S019594170003099X_ref010","doi-asserted-by":"publisher","DOI":"10.1086\/513204"},{"key":"S019594170003099X_ref021","doi-asserted-by":"publisher","DOI":"10.1086\/504937"},{"key":"S019594170003099X_ref018","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.00575_10.x"},{"key":"S019594170003099X_ref011","doi-asserted-by":"publisher","DOI":"10.1086\/519846"},{"key":"S019594170003099X_ref014","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2009.06.005"},{"key":"S019594170003099X_ref003","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181aa6c3e"},{"key":"S019594170003099X_ref006","doi-asserted-by":"publisher","DOI":"10.1086\/380100"},{"key":"S019594170003099X_ref001","doi-asserted-by":"publisher","DOI":"10.1038\/89098"},{"key":"S019594170003099X_ref007","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e318162a164"},{"key":"S019594170003099X_ref020","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000207395.80657.cf"},{"key":"S019594170003099X_ref015","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2009.259"},{"key":"S019594170003099X_ref016","volume-title":"Influenza: Reports and Surveillance Methods in the United States"},{"key":"S019594170003099X_ref012","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31822702fe"},{"key":"S019594170003099X_ref004","doi-asserted-by":"publisher","DOI":"10.3201\/eid1401.070251"},{"key":"S019594170003099X_ref013","doi-asserted-by":"publisher","DOI":"10.1086\/655161"},{"key":"S019594170003099X_ref017","doi-asserted-by":"publisher","DOI":"10.1542\/peds.102.1.137"},{"key":"S019594170003099X_ref009","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01959-08"},{"key":"S019594170003099X_ref005","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000126401.21779.74"},{"key":"S019594170003099X_ref008","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268808000666"},{"key":"S019594170003099X_ref019","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.11.5520-5525.2005"}],"container-title":["Infection Control &amp; Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S019594170003099X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T09:17:02Z","timestamp":1649236622000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S019594170003099X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S019594170003099X"],"URL":"https:\/\/doi.org\/10.1086\/665727","relation":{},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6]]}}}