{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T05:29:42Z","timestamp":1792301382156,"version":"4.4.0"},"reference-count":11,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T00:00:00Z","timestamp":1420156800000},"content-version":"unspecified","delay-in-days":731,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infect. Control Hosp. Epidemiol."],"published-print":{"date-parts":[[2013,1]]},"abstract":"\n Objective.<\/jats:title>\n To describe antimicrobial resistance patterns for healthcare-associated infections (HAIs) reported to the National Healthcare Safety Network (NHSN) during 2009-2010.<\/jats:p>\n <\/jats:sec>\n \n Methods.<\/jats:title>\n Central line-associated bloodstream infections, catheter-associated urinary tract infections, ventilator-associated pneumonia, and surgical site infections were included. Pooled mean proportions of isolates interpreted as resistant (or, in some cases, nonsusceptible) to selected antimicrobial agents were calculated by type of HAI and compared to historical data.<\/jats:p>\n <\/jats:sec>\n \n Results.<\/jats:title>\n \n Overall, 2,039 hospitals reported 1 or more HAIs; 1,749 (86%) were general acute care hospitals, and 1,143 (56%) had fewer than 200 beds. There were 69,475 HAIs and 81,139 pathogens reported. Eight pathogen groups accounted for about 80% of reported pathogens:\n Staphylococcus aureus<\/jats:italic>\n (16%),\n Enterococcus<\/jats:italic>\n spp. (14%),\n Escherichia coli<\/jats:italic>\n (12%), coagulase-negative staphylococci (11%),\n Candida<\/jats:italic>\n spp. (9%),\n Klebsiella pneumoniae<\/jats:italic>\n (and\n Klebsiella oxytoca<\/jats:italic>\n ; 8%),\n Pseudomonas aeruginosa<\/jats:italic>\n (8%), and\n Enterobacter<\/jats:italic>\n spp. (5%). The percentage of resistance was similar to that reported in the previous 2-year period, with a slight decrease in the percentage of\n S. aureus<\/jats:italic>\n resistant to oxacillins (MRSA). Nearly 20% of pathogens reported from all HAIs were the following multidrug-resistant phenotypes: MRSA (8.5%); vancomycin-resistant\n Enterococcus<\/jats:italic>\n (3%); extended-spectrum cephalosporin-resistant\n K. pneumoniae<\/jats:italic>\n and\n K. oxytoca<\/jats:italic>\n (2%),\n E. coli<\/jats:italic>\n (2%), and\n Enterobacter<\/jats:italic>\n spp. (2%); and carbapenem-resistant\n P. aeruginosa<\/jats:italic>\n (2%),\n K. pneumoniae\/oxytoca<\/jats:italic>\n (<1%),\n E, coli<\/jats:italic>\n (<1%), and\n Enterobacter<\/jats:italic>\n spp. (<1%). Among facilities reporting HAIs with 1 of the above gram-negative bacteria, 20%-40% reported at least 1 with the resistant phenotype.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion.<\/jats:title>\n While the proportion of resistant isolates did not substantially change from that in the previous 2 years, multidrug-resistant gram-negative phenotypes were reported from a moderate proportion of facilities.<\/jats:p>\n <\/jats:sec>","DOI":"10.1086\/668770","type":"journal-article","created":{"date-parts":[[2012,11,27]],"date-time":"2012-11-27T18:11:29Z","timestamp":1354039889000},"page":"1-14","source":"Crossref","is-referenced-by-count":1358,"title":["Antimicrobial-Resistant Pathogens Associated with Healthcare-Associated Infections Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009\u20132010"],"prefix":"10.1017","volume":"34","author":[{"given":"Dawn M.","family":"Sievert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Ricks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan R.","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjun","family":"Srinivasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Kallen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandi","family":"Limbago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Fridkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"National Healthcare Safety Network (NHSN) Team and Participating NHSN Facilities","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,1,2]]},"reference":[{"key":"S0195941700031921_ref002","unstructured":"CDC. The National Healthcare Safety Network (NHSN) Manual. Patient Safety Component Protocol. Centers for Disease Control and Prevention website, http:\/\/www.cdc.gov\/ncidod \/dhqp\/pdf\/nhsn\/NHSN_Manual_PatientSafetyProtocol_CURRENT.pdf. Published 2008."},{"key":"S0195941700031921_ref005","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.7139"},{"key":"S0195941700031921_ref003","volume-title":"Performance standards for antimicrobial susceptibility testing-sixteenth informational supplement","year":"2008"},{"key":"S0195941700031921_ref009","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00576-07"},{"key":"S0195941700031921_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(06)70689-2"},{"key":"S0195941700031921_ref007","doi-asserted-by":"publisher","DOI":"10.1086\/652152"},{"key":"S0195941700031921_ref011","doi-asserted-by":"publisher","DOI":"10.1086\/657583"},{"key":"S0195941700031921_ref006","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1115"},{"key":"S0195941700031921_ref001","doi-asserted-by":"publisher","DOI":"10.1086\/591861"},{"key":"S0195941700031921_ref004","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03570.x"},{"key":"S0195941700031921_ref010","doi-asserted-by":"publisher","DOI":"10.1086\/421495"}],"container-title":["Infection Control & Hospital Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0195941700031921","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T16:07:18Z","timestamp":1556122038000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0195941700031921\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0195941700031921"],"URL":"https:\/\/doi.org\/10.1086\/668770","relation":{"is-referenced-by":[{"id-type":"doi","id":"10.1007\/s13197-025-06327-7","asserted-by":"object"}]},"ISSN":["0899-823X","1559-6834"],"issn-type":[{"value":"0899-823X","type":"print"},{"value":"1559-6834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}