{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:57:34Z","timestamp":1789181854393,"version":"build-2803163510"},"reference-count":16,"publisher":"IOP Publishing","issue":"2","license":[{"start":{"date-parts":[[2015,12,30]],"date-time":"2015-12-30T00:00:00Z","timestamp":1451433600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/publishingsupport.iopscience.iop.org\/iop-standard\/v1"},{"start":{"date-parts":[[2015,12,30]],"date-time":"2015-12-30T00:00:00Z","timestamp":1451433600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100006599","name":"Focused Ultrasound Foundation","doi-asserted-by":"crossref","award":["FUS307R1"],"award-info":[{"award-number":["FUS307R1"]}],"id":[{"id":"10.13039\/100006599","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Brain Canada Multi-Investigator Research Initiative"}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Phys. Med. Biol."],"published-print":{"date-parts":[[2016,1,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Magnetic resonance acoustic radiation force imaging (MR-ARFI) allows the quantification of microscopic displacements induced by ultrasound pulses, which are proportional to the local acoustic intensity. This study describes a new method to acquire MR-ARFI maps, which reduces the measurement noise in the quantification of displacement as well as improving its robustness in the presence of motion.<\/jats:p>\n                  <jats:p>Two MR-ARFI sequences were compared in this study. The first sequence \u2018variable MSG\u2019 involves switching the polarity of the motion sensitive gradient (MSG) between odd and even image frames. The second sequence named \u2018static MSG\u2019 involves a variable ultrasound trigger delay to sonicate during the first or second MSG for odd and even image frames, respectively. As previously published, the data acquired with a variable MSG required the use of reference data acquired prior to any sonication to process displacement maps. In contrary, data acquired with a static MSG were converted to displacement maps without using reference data acquired prior to the sonication. Displacement maps acquired with both sequences were compared by performing sonications for three different conditions: in a polyacrylamide phantom, in the leg muscle of a freely breathing pig and in the leg muscle of pig under apnea.<\/jats:p>\n                  <jats:p>\n                    The comparison of images acquired at even image frames and odd image frames indicates that the sequence with a static MSG provides a significantly better steady state (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009\u2009&lt;\u2009\u20090.001 based on a Student\u2019s t-test) than the images acquired with a variable MSG. In addition no reference data prior to sonication were required to process displacement maps for data acquired with a static MSG. The absence of reference data prior to sonication provided a 41% reduction of the spatial distribution of noise (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009\u2009&lt;\u2009\u20090.001 based on a Student\u2019s t-test) and reduced the sensitivity to motion for displacements acquired with a static MSG. No significant differences were expected and observed for thermal maps acquired with a variable MSG and a static MSG.\n                  <\/jats:p>\n                  <jats:p>The use of a static MSG with a variable ultrasound trigger delay improves the ARFI displacement map quality without additional acquisition time and remains compatible with the simultaneous acquisition of MR thermal maps.<\/jats:p>","DOI":"10.1088\/0031-9155\/61\/2\/712","type":"journal-article","created":{"date-parts":[[2015,12,30]],"date-time":"2015-12-30T08:13:23Z","timestamp":1451463203000},"page":"712-727","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":10,"title":["Variable ultrasound trigger delay for improved magnetic resonance acoustic radiation force imaging"],"prefix":"10.1088","volume":"61","author":[{"given":"Charles","family":"Mougenot","sequence":"first","affiliation":[{"name":"Philips Healthcare"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Waspe","sequence":"additional","affiliation":[{"name":"555 University Avenue"},{"name":"University of Toronto"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Looi","sequence":"additional","affiliation":[{"name":"555 University Avenue"},{"name":"University of Toronto"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James M","family":"Drake","sequence":"additional","affiliation":[{"name":"555 University Avenue"},{"name":"University of Toronto"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2015,12,30]]},"reference":[{"key":"pmbaa0d3bbib001","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1002\/mrm.23309","type":"journal-article","article-title":"ARFI-prepared MRgHIFU in liver: simultaneous mapping of ARFI-displacement and temperature elevation, using a fast GRE-EPI sequence","volume":"68","author":"Auboiroux","year":"2012","journal-title":"Magn. 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All rights, including for text and data mining, AI training, and similar technologies, are reserved.","name":"copyright_information","label":"Copyright Information"},{"value":"2015-08-28","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2015-12-02","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2015-12-30","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}