{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T02:22:21Z","timestamp":1768702941688,"version":"3.49.0"},"reference-count":35,"publisher":"IOP Publishing","issue":"2","license":[{"start":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T00:00:00Z","timestamp":1718323200000},"content-version":"vor","delay-in-days":13,"URL":"https:\/\/iopscience.iop.org\/page\/copyright"},{"start":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T00:00:00Z","timestamp":1718323200000},"content-version":"tdm","delay-in-days":13,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["12175043"],"award-info":[{"award-number":["12175043"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Science and Technology Development Fund of Shanghai Pudong New Area","award":["PKJ2021-Y47"],"award-info":[{"award-number":["PKJ2021-Y47"]}]},{"name":"Shanghai Committee of Science and Technology, China","award":["23ZR1460200"],"award-info":[{"award-number":["23ZR1460200"]}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["J. Radiol. Prot."],"published-print":{"date-parts":[[2024,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The measurement of linear energy transfer (LET) is crucial for the evaluation of the radiation effect in heavy ion therapy. As two detectors which are convenient to implant into the phantom, the performance of CR-39 and thermoluminescence detector (TLD) for LET measurement was compared by experiment and simulation in this study. The results confirmed the applicability of both detectors for LET measurements, but also revealed that the CR-39 detector would lead to potential overestimation of dose-averaged LET compared with the simulation by PHITS, while the TLD would have a large uncertainty measuring ions with LET larger than 20 keV <jats:italic>\u03bc<\/jats:italic>m<jats:sup>\u22121<\/jats:sup>. The results of this study were expected to improve the detection method of LET for therapeutic carbon beam and would finally be benefit to the quality assurance of heavy ion radiotherapy.<\/jats:p>","DOI":"10.1088\/1361-6498\/ad53d9","type":"journal-article","created":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T18:22:43Z","timestamp":1717525363000},"page":"021522","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of linear energy transfer measurement for therapeutic carbon beam using CR-39 and TLD"],"prefix":"10.1088","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6964-9385","authenticated-orcid":true,"given":"Zhou","family":"Yuan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weihai","family":"Zhuo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiyan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiling","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingfang","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6606-431X","authenticated-orcid":true,"given":"Bo","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"266","published-online":{"date-parts":[[2024,6,14]]},"reference":[{"key":"jrpad53d9bib1","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6560\/aafa46","article-title":"Investigation of single carbon ion fragmentation in water and PMMA for hadron therapy","volume":"64","author":"Aric\u00f2","year":"2019","journal-title":"Phys. Med. Biol."},{"key":"jrpad53d9bib2","doi-asserted-by":"publisher","first-page":"8003","DOI":"10.1088\/1361-6560\/aa875e","article-title":"Investigation of mixed ion fields in the forward direction for 220.5 MeV\/u helium ion beams: comparison between water and PMMA targets","volume":"62","author":"Aric\u00f2","year":"2017","journal-title":"Phys. Med. Biol."},{"key":"jrpad53d9bib3","doi-asserted-by":"publisher","DOI":"10.1016\/j.radphyschem.2020.108730","article-title":"Microdosimetry with a sealed mini-TEPC and a silicon telescope at a clinical proton SOBP of CATANA","volume":"171","author":"Bianchi","year":"2020","journal-title":"Radiat. Phys. Chem."},{"key":"jrpad53d9bib4","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.radmeas.2009.11.006","article-title":"On the correctness of the thermoluminescent high-temperature ratio (HTR) method for estimating ionization density effects in mixed radiation fields","volume":"45","author":"Bilski","year":"2010","journal-title":"Radiat. Meas."},{"key":"jrpad53d9bib5","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1016\/j.radmeas.2009.10.089","article-title":"Track etch based LET spectrometry in beams of neutrons with energies from 0.2 to 200MeV","volume":"44","author":"Brabcova","year":"2009","journal-title":"Radiat. Meas."},{"key":"jrpad53d9bib6","doi-asserted-by":"publisher","first-page":"3123","DOI":"10.1002\/mp.14177","article-title":"Experimental investigation of the characteristics of radioactive beams for heavy ion therapy","volume":"47","author":"Chacon","year":"2020","journal-title":"Med. Phys."},{"key":"jrpad53d9bib7","doi-asserted-by":"publisher","first-page":"8262","DOI":"10.1038\/s41598-022-10575-4","article-title":"Improved simultaneous LET and dose measurements in proton therapy","volume":"12","author":"Christensen","year":"2022","journal-title":"Sci. Rep."},{"key":"jrpad53d9bib8","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1038\/s42254-021-00368-5","article-title":"Physics and biomedical challenges of cancer therapy with accelerated heavy ions","volume":"3","author":"Durante","year":"2021","journal-title":"Nat. Rev. Phys."},{"key":"jrpad53d9bib9","doi-asserted-by":"publisher","author":"Fleischer","year":"2024","DOI":"10.1525\/9780520320239"},{"key":"jrpad53d9bib10","doi-asserted-by":"publisher","first-page":"4295","DOI":"10.1088\/0031-9155\/59\/15\/4295","article-title":"Calibration of the Al2O3:C optically stimulated luminescence (OSL) signal for linear energy transfer (LET) measurements in therapeutic proton beams","volume":"59","author":"Granville","year":"2014a","journal-title":"Phys. Med. Biol."},{"key":"jrpad53d9bib11","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.radmeas.2014.03.026","article-title":"Linear energy transfer dependence of Al0O3:C optically stimulated luminescence detectors exposed to therapeutic proton beams","volume":"71","author":"Granville","year":"2014b","journal-title":"Radiat. Meas."},{"key":"jrpad53d9bib12","doi-asserted-by":"publisher","first-page":"1765","DOI":"10.1088\/0031-9155\/61\/4\/1765","article-title":"Simultaneous measurements of absorbed dose and linear energy transfer in therapeutic proton beams","volume":"61","author":"Granville","year":"2016","journal-title":"Phys. Med. Biol."},{"key":"jrpad53d9bib13","doi-asserted-by":"publisher","first-page":"N283","DOI":"10.1088\/0031-9155\/60\/14\/N283","article-title":"Comparison of linear energy transfer scoring techniques in Monte Carlo simulations of proton beams","volume":"60","author":"Granville","year":"2015","journal-title":"Phys. Med. Biol."},{"key":"jrpad53d9bib14","doi-asserted-by":"publisher","first-page":"6234","DOI":"10.1118\/1.4932217","article-title":"Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant4 Monte Carlo code","volume":"42","author":"Guan","year":"2015","journal-title":"Med. Phys."},{"key":"jrpad53d9bib15","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6560\/aadaa6","article-title":"Linear energy transfer (LET) spectra and survival fraction distribution based on the CR-39 plastic charged-particle detector in a spread-out Bragg peak irradiation by a 12C beam","volume":"63","author":"Hirano","year":"2018","journal-title":"Phys. Med. Biol."},{"key":"jrpad53d9bib16","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1093\/oxfordjournals.rpd.a006337","article-title":"On the use of LiF:Mg,Ti TLDs in space\u2014a critical review","volume":"106","author":"Horowitz","year":"2003","journal-title":"Radiat. Prot. Dosim."},{"key":"jrpad53d9bib17","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1093\/jicru\/ndi013","article-title":"Stopping of ions heavier than Helium","volume":"5","author":"ICRU","year":"2005","journal-title":"J. ICRU"},{"key":"jrpad53d9bib18","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1093\/jicru\/ndw030","article-title":"Key data for ionizing-radiation dosimetry: measurement standards and applications","volume":"14","author":"ICRU","year":"2014","journal-title":"J. ICRU"},{"key":"jrpad53d9bib19","doi-asserted-by":"publisher","first-page":"4532","DOI":"10.1002\/mp.14905","article-title":"In-field and out-of-field microdosimetric characterisation of a 62 MeV proton beam at CATANA","volume":"48","author":"James","year":"2021","journal-title":"Med. Phys."},{"key":"jrpad53d9bib20","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.nimb.2016.07.002","article-title":"A performance test of a new high-surface-quality and high-sensitivity CR-39 plastic nuclear track detector\u2014TechnoTrak","volume":"383","author":"Kodaira","year":"2016","journal-title":"Nucl. Instrum. Methods Phys. Res. B"},{"key":"jrpad53d9bib21","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.nima.2007.01.086","article-title":"New method of the precise measurement for the thickness and bulk etch rate of the solid-state track detector","volume":"574","author":"Kodaira","year":"2007","journal-title":"Nucl. Instrum. Methods Phys. Res. A"},{"key":"jrpad53d9bib22","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1016\/j.radmeas.2012.10.001","article-title":"Calibration of CR-39 with atomic force microscope for the measurement of short range tracks from proton-induced target fragmentation reactions","volume":"50","author":"Kodaira","year":"2013","journal-title":"Radiat. Meas."},{"key":"jrpad53d9bib23","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6560\/abd66f","article-title":"Estimating the biological effects of helium, carbon, oxygen, and neon ion beams using 3D silicon microdosimeters","volume":"66","author":"Lee","year":"2021","journal-title":"Phys. Med. Biol."},{"key":"jrpad53d9bib24","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.radphyschem.2014.09.001","article-title":"Radiological characteristics of MRI-based VIP polymer gel under carbon beam irradiation","volume":"107","author":"Maeyama","year":"2015","journal-title":"Radiat. Phys. Chem."},{"key":"jrpad53d9bib25","doi-asserted-by":"publisher","DOI":"10.1063\/1.4917418","article-title":"Proposed linear energy transfer areal detector for protons using radiochromic film","volume":"86","author":"Mayer","year":"2015","journal-title":"Rev. Sci. Instrum."},{"key":"jrpad53d9bib26","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6560\/aaff20","article-title":"A novel methodology to assess linear energy transfer and relative biological effectiveness in proton therapy using pairs of differently doped thermoluminescent detectors","volume":"64","author":"Parisi","year":"2019","journal-title":"Phys. Med. Biol."},{"key":"jrpad53d9bib27","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/j.radmeas.2006.03.008","article-title":"GlowFit\u2014a new tool for thermoluminescence glow-curve deconvolution","volume":"41","author":"Puchalska","year":"2006","journal-title":"Radiat. Meas."},{"key":"jrpad53d9bib28","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.nima.2016.02.038","article-title":"Measurement of LET (linear energy transfer) spectra using CR-39 at different depths of water irradiated by 171MeV protons: a comparison with Monte Carlo simulation","volume":"818","author":"Sahoo","year":"2016","journal-title":"Nucl. Instrum. Methods Phys. Res. A"},{"key":"jrpad53d9bib29","doi-asserted-by":"publisher","DOI":"10.1016\/j.radphyschem.2020.109078","article-title":"Microdosimetry with a 3D silicon on insulator (SOI) detector in a low energy proton beamline","volume":"176","author":"Samn\u00f8y","year":"2020","journal-title":"Radiat. Phys. Chem."},{"key":"jrpad53d9bib30","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1080\/00223131.2023.2275736","article-title":"Recent improvements of the particle and heavy ion transport code system\u2014PHITS version 3.33","volume":"61","author":"Sato","year":"2024","journal-title":"J. Nucl. Sci. Technol."},{"key":"jrpad53d9bib31","doi-asserted-by":"publisher","DOI":"10.1016\/j.radmeas.2020.106356","article-title":"Thermoluminescence efficiency and glow curves of Cr-doped Al2O3 ceramic TLD for a wide linear energy transfer range","volume":"134","author":"Shimomura","year":"2020","journal-title":"Radiat. Meas."},{"key":"jrpad53d9bib32","doi-asserted-by":"publisher","first-page":"197","DOI":"10.4236\/ijmpcero.2017.62018","article-title":"LET monitoring using liquid ionization chambers","volume":"06","author":"Tegami","year":"2017","journal-title":"Int. J. Med. Phys. Clin. Eng. Radiat. Oncol."},{"key":"jrpad53d9bib33","doi-asserted-by":"publisher","DOI":"10.1016\/j.radphyschem.2022.110193","article-title":"Measurements of linear energy transfer (LET) distributions by CR-39 for a therapeutic carbon ion beam with a new 2D ripple filter","volume":"197","author":"Yang","year":"2022a","journal-title":"Radiat. Phys. Chem."},{"key":"jrpad53d9bib34","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1088\/1361-6498\/abd88c","article-title":"Measurement of therapeutic 12C beam in a water phantom using CR-39","volume":"41","author":"Yang","year":"2021","journal-title":"J. Radiol. Prot."},{"key":"jrpad53d9bib35","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6498\/ac6044","article-title":"Changes of the linear energy transfer (LET) and beam width of therapeutic carbon ion beam in density heterogeneous phantoms","volume":"42","author":"Yang","year":"2022b","journal-title":"J. Radiol. Prot."}],"container-title":["Journal of Radiological Protection"],"original-title":[],"link":[{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6498\/ad53d9","content-type":"text\/html","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6498\/ad53d9\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6498\/ad53d9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6498\/ad53d9\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6498\/ad53d9\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6498\/ad53d9\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6498\/ad53d9\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"similarity-checking"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6498\/ad53d9\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T10:48:47Z","timestamp":1755946127000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6498\/ad53d9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,1]]},"references-count":35,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,6,14]]},"published-print":{"date-parts":[[2024,6,1]]}},"URL":"https:\/\/doi.org\/10.1088\/1361-6498\/ad53d9","relation":{},"ISSN":["0952-4746","1361-6498"],"issn-type":[{"value":"0952-4746","type":"print"},{"value":"1361-6498","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,1]]},"assertion":[{"value":"Comparison of linear energy transfer measurement for therapeutic carbon beam using CR-39 and TLD","name":"article_title","label":"Article Title"},{"value":"Journal of Radiological Protection","name":"journal_title","label":"Journal Title"},{"value":"paper","name":"article_type","label":"Article Type"},{"value":"\u00a9 2024 Society for Radiological Protection. Published on behalf of SRP by IOP Publishing Limited. All rights reserved. All rights, including for text and data mining, AI training, and similar technologies, are reserved.","name":"copyright_information","label":"Copyright Information"},{"value":"2024-04-15","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2024-06-04","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2024-06-14","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}