{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:38:33Z","timestamp":1790163513027,"version":"4.1.0"},"reference-count":123,"publisher":"IOP Publishing","issue":"43","license":[{"start":{"date-parts":[[2017,10,2]],"date-time":"2017-10-02T00:00:00Z","timestamp":1506902400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"},{"start":{"date-parts":[[2017,10,2]],"date-time":"2017-10-02T00:00:00Z","timestamp":1506902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003975","name":"The Israel Cancer Association","doi-asserted-by":"crossref","award":["2015-0116"],"award-info":[{"award-number":["2015-0116"]}],"id":[{"id":"10.13039\/501100003975","id-type":"DOI","asserted-by":"crossref"}]},{"name":"ERC-STG","award":["2015-0116"],"award-info":[{"award-number":["2015-0116"]}]},{"DOI":"10.13039\/501100003977","name":"The Israel Science Foundation","doi-asserted-by":"crossref","award":["1778\/13"],"award-info":[{"award-number":["1778\/13"]}],"id":[{"id":"10.13039\/501100003977","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Kamin Grant","award":["52752"],"award-info":[{"award-number":["52752"]}]},{"name":"The Israel Ministry of Science Technology and Space","award":["3-11878"],"award-info":[{"award-number":["3-11878"]}]},{"name":"ERC-STG-2015","award":["680242"],"award-info":[{"award-number":["680242"]}]},{"name":"The European Union FP-7 IRG Program for a Career Integration Grant","award":["908049"],"award-info":[{"award-number":["908049"]}]},{"name":"the German-Israeli Foundation for Scientific Research and Development for a GIF Young grant","award":["I-2328-1139.10\/2012"],"award-info":[{"award-number":["I-2328-1139.10\/2012"]}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":true},"short-container-title":["Nanotechnology"],"published-print":{"date-parts":[[2017,10,27]]},"DOI":"10.1088\/1361-6528\/aa8a3d","type":"journal-article","created":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T09:15:22Z","timestamp":1504602922000},"page":"43LT01","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":37,"title":["Nanoparticles target early-stage breast cancer metastasis<i>in vivo<\/i>"],"prefix":"10.1088","volume":"28","author":[{"given":"Evgeniya","family":"Goldman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7894-486X","authenticated-orcid":false,"given":"Assaf","family":"Zinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zvi","family":"Yaari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashima","family":"Kajal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dikla","family":"Vardi-Oknin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mor","family":"Goldfeder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josh E.","family":"Schroeder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janna","family":"Shainsky-Roitman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dov","family":"Hershkovitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avi","family":"Schroeder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2017,10,2]]},"reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21332"},{"key":"2","author":"Horner M","year":"2009","journal-title":"SEER Cancer Statistics Review, 1975\u20132006"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20134"},{"key":"4","first-page":"512","volume":"35","author":"Butler T P","year":"1975","journal-title":"Cancer Res."},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.26.14608"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1038\/nature20785"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1038\/nature17038"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3180"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.09.024"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-013-2998-2"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1893"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1984.2.11.1281"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200103153441101"},{"key":"14","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1158\/1078-0432.728.11.2","volume":"11","author":"Demaria S","year":"2005","journal-title":"Clin. Cancer Res.","ISSN":"https:\/\/id.crossref.org\/issn\/1078-0432","issn-type":"print"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1096\/fj.09-149641"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aaf7374"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1038\/natrevmats.2016.69"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200906684"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.5b00276"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2012.01.020"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1038\/nmat3780"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1566"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.6b08244"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.5b04237"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1601039"},{"key":"26","doi-asserted-by":"crossref","DOI":"10.1088\/1758-5082\/6\/2\/020301","volume":"6","author":"Shapira A","year":"2014","journal-title":"Biofabrication","ISSN":"https:\/\/id.crossref.org\/issn\/1758-5090","issn-type":"print"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.2165\/11538150-000000000-00000"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aag1802"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2007.387"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1038\/nrd4333"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.2147\/ijn.s34157"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2013.02.020"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1593\/neo.03460"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.12.51"},{"key":"35","first-page":"6387","volume":"46","author":"Matsumura Y","year":"1986","journal-title":"Cancer Res."},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1038\/nrc.2016.108"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1021\/mp200083n"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.4161\/cc.5.16.3018"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1038\/35025220"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.8.4607"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2010.139"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-008-9562-y"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1377"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1996.03540220042028"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1089\/153968503321642615"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-3659(99)00248-5"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200342050-00002"},{"key":"48","first-page":"243","volume":"7","author":"Harrington K J","year":"2001","journal-title":"Clin. Cancer Res.","ISSN":"https:\/\/id.crossref.org\/issn\/1078-0432","issn-type":"print"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2005.05.049"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1007\/s00280-007-0525-5"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1007\/s10544-008-9209-0"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-12-4561"},{"key":"53","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2012.05.013"},{"key":"54","first-page":"1005","volume":"9","author":"Hafner A","year":"2014","journal-title":"Int. J. Nanomed."},{"key":"55","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S65526"},{"key":"56","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S46900"},{"key":"57","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.15.21"},{"key":"58","author":"Evers P","year":"2015"},{"key":"59","doi-asserted-by":"publisher","DOI":"10.1021\/mp200394t"},{"key":"60","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.03.020"},{"key":"61","doi-asserted-by":"publisher","DOI":"10.3816\/CBC.2003.n.037"},{"key":"62","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199809243391307"},{"key":"63","doi-asserted-by":"publisher","DOI":"10.2147\/ijn.s3061"},{"key":"64","doi-asserted-by":"publisher","DOI":"10.1021\/la0631668"},{"key":"65","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201700374"},{"key":"66","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.10.077"},{"key":"67","doi-asserted-by":"publisher","DOI":"10.1139\/o59-099"},{"key":"68","author":"Tamer Elbayoumi V T ed Berezin M Y","year":"2015","journal-title":"Nanotechnology for Biomedical Imaging and Diagnostics: From Nanoparticle Design to Clinical Applications"},{"key":"69","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4419-0685-4_1"},{"key":"70","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.02.013"},{"key":"71","author":"","year":"2016"},{"key":"72","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp0708307"},{"key":"73","doi-asserted-by":"publisher","DOI":"10.1186\/bcr2737"},{"key":"74","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2016.66"},{"key":"75","author":"Weinberg R","year":"2007","journal-title":"Biology of Cancer Garland Science"},{"key":"76","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)49915-0"},{"key":"77","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2014.08.019"},{"key":"78","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3001"},{"key":"79","doi-asserted-by":"crossref","first-page":"297","DOI":"10.2217\/17435889.1.3.297","volume":"1","author":"Immordino M L","year":"2006","journal-title":"Int. J. Nanomed."},{"key":"80","doi-asserted-by":"publisher","DOI":"10.1038\/nature08956"},{"key":"81","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S29147"},{"key":"82","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2012.45"},{"key":"83","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2010.05.001"},{"key":"84","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65006-7"},{"key":"85","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.98.2.398"},{"key":"86","doi-asserted-by":"publisher","DOI":"10.3109\/08982109409037068"},{"key":"87","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3330"},{"key":"88","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b00376"},{"key":"89","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2011.11.024"},{"key":"90","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3227"},{"key":"91","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-007-9438-0"},{"key":"92","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2013.4517"},{"key":"93","doi-asserted-by":"publisher","DOI":"10.5306\/wjco.v5.i2.82"},{"key":"94","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-008-0085-x"},{"key":"95","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2002.127544"},{"key":"96","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1098"},{"key":"97","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.11.025"},{"key":"98","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2622"},{"key":"99","doi-asserted-by":"publisher","DOI":"10.1038\/nm0806-875"},{"key":"100","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.12.013"},{"key":"101","doi-asserted-by":"publisher","DOI":"10.1084\/jem.138.4.745"},{"key":"102","doi-asserted-by":"publisher","DOI":"10.1038\/7895"},{"key":"103","doi-asserted-by":"publisher","DOI":"10.1038\/nature06487"},{"key":"104","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1974"},{"key":"105","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2627"},{"key":"106","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(94)90200-3"},{"key":"107","doi-asserted-by":"publisher","DOI":"10.1038\/nrc.2017.6"},{"key":"108","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2014.533"},{"key":"109","doi-asserted-by":"publisher","DOI":"10.3109\/02841869709109228"},{"key":"110","first-page":"1957","volume":"9","author":"Wachsberger P","year":"2003","journal-title":"Clin. Cancer Res.","ISSN":"https:\/\/id.crossref.org\/issn\/1078-0432","issn-type":"print"},{"key":"111","doi-asserted-by":"publisher","DOI":"10.1038\/sj.neo.7900129"},{"key":"112","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1521265113"},{"key":"113","doi-asserted-by":"publisher","DOI":"10.1016\/j.molonc.2008.04.001"},{"key":"114","doi-asserted-by":"publisher","DOI":"10.1126\/science.935859"},{"key":"115","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2621"},{"key":"116","doi-asserted-by":"publisher","DOI":"10.1038\/nrc865"},{"key":"117","doi-asserted-by":"publisher","DOI":"10.1038\/nature06385"},{"key":"118","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa040766"},{"key":"119","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200408130"},{"key":"120","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-4382"},{"key":"121","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0701138104"},{"key":"122","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms2856"},{"key":"123","doi-asserted-by":"publisher","DOI":"10.1038\/nature04186"}],"container-title":["Nanotechnology"],"original-title":[],"link":[{"URL":"http:\/\/stacks.iop.org\/0957-4484\/28\/i=43\/a=43LT01?key=crossref.406677fc2e720722d71ca6de80fc4e7b","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/aa8a3d\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"text-mining"},{"URL":"http:\/\/stacks.iop.org\/0957-4484\/28\/i=43\/a=43LT01\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/aa8a3d","content-type":"text\/html","content-version":"am","intended-application":"text-mining"},{"URL":"http:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/aa8a3d\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/aa8a3d\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"similarity-checking"},{"URL":"http:\/\/stacks.iop.org\/0957-4484\/28\/i=43\/a=43LT01\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/stacks.iop.org\/0957-4484\/28\/i=43\/a=43LT01?key=crossref.406677fc2e720722d71ca6de80fc4e7b","content-type":"text\/html","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T05:39:05Z","timestamp":1659418745000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/aa8a3d"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,2]]},"references-count":123,"journal-issue":{"issue":"43","published-print":{"date-parts":[[2017,10,27]]}},"URL":"https:\/\/doi.org\/10.1088\/1361-6528\/aa8a3d","relation":{},"ISSN":["0957-4484","1361-6528"],"issn-type":[{"value":"0957-4484","type":"print"},{"value":"1361-6528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,2]]},"assertion":[{"value":"Nanotechnology","name":"journal_title","label":"Journal title"},{"value":"lett","name":"article_type","label":"Article type"},{"value":"Nanoparticles target early-stage breast cancer metastasisin vivo","name":"article_title","label":"Article title"},{"value":"\u00a9 2017 IOP Publishing Ltd","name":"copyright_information","label":"Copyright information"},{"value":"cc-by Original content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.","name":"license_information","label":"License information"},{"value":"2017-07-21","name":"date_received","label":"Date received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2017-09-05","name":"date_accepted","label":"Date accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2017-10-02","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}