{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:05:02Z","timestamp":1785801902940,"version":"3.56.0"},"reference-count":161,"publisher":"IOP Publishing","issue":"33","license":[{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/page\/copyright"},{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/iopscience.iop.org\/info\/page\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004621","name":"Kerman University of Medical Sciences","doi-asserted-by":"crossref","award":["401000143"],"award-info":[{"award-number":["401000143"]}],"id":[{"id":"10.13039\/501100004621","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["iopscience.iop.org"],"crossmark-restriction":false},"short-container-title":["Nanotechnology"],"published-print":{"date-parts":[[2024,8,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>\n                  <jats:italic>Candida auris<\/jats:italic>, a rapidly emerging multidrug-resistant fungal pathogen, poses a global health threat, with cases reported in over 47 countries. Conventional detection methods struggle, and the increasing resistance of <jats:italic>C. auris<\/jats:italic> to antifungal agents has limited treatment options. Nanoparticle-based therapies, utilizing materials like silver, carbon, zinc oxide, titanium dioxide, polymer, and gold, show promise in effectively treating cutaneous candidiasis. This review explores recent advancements in nanoparticle-based therapies, emphasizing their potential to revolutionize antifungal therapy, particularly in combating <jats:italic>C. auris<\/jats:italic> infections. The discussion delves into mechanisms of action, combinations of nanomaterials, and their application against multidrug-resistant fungal pathogens, offering exciting prospects for improved clinical outcomes and reduced mortality rates. The aim is to inspire further research, ushering in a new era in the fight against multidrug-resistant fungal infections, paving the way for more effective and targeted therapeutic interventions.<\/jats:p>","DOI":"10.1088\/1361-6528\/ad4bed","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T22:21:26Z","timestamp":1715811686000},"page":"332001","update-policy":"https:\/\/doi.org\/10.1088\/crossmark-policy","source":"Crossref","is-referenced-by-count":10,"title":["Advancements in nanoparticle-based therapies for multidrug-resistant candidiasis infections: a comprehensive review"],"prefix":"10.1088","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3544-829X","authenticated-orcid":false,"given":"Alireza","family":"Izadi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Paknia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Roostaee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Amin Ayatollahi","family":"Mousavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1711-2522","authenticated-orcid":true,"given":"Mahmood","family":"Barani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"266","published-online":{"date-parts":[[2024,5,30]]},"reference":[{"key":"nanoad4bedbib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41579-022-00720-1","article-title":"Tackling the emerging threat of antifungal resistance to human health","volume":"20","author":"Fisher","year":"2022","journal-title":"Nat. Rev. Microbiol."},{"key":"nanoad4bedbib2","doi-asserted-by":"publisher","first-page":"1020","DOI":"10.1016\/j.chom.2022.04.013","article-title":"Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria","volume":"30","author":"Drummond","year":"2022","journal-title":"Cell Host Microbe"},{"key":"nanoad4bedbib3","first-page":"113","article-title":"Fungi\u2014a component of the oral microbiome involved in periodontal diseases","author":"Karkowska-Kuleta","year":"2022"},{"key":"nanoad4bedbib4","doi-asserted-by":"publisher","DOI":"10.1172\/JCI155786","article-title":"Fungal microbiome in inflammatory bowel disease: a critical assessment","volume":"132","author":"Underhill","year":"2022","journal-title":"J. Clin. Invest."},{"key":"nanoad4bedbib5","doi-asserted-by":"publisher","first-page":"2621","DOI":"10.2147\/CCID.S391360","article-title":"Intrinsic atopic dermatitis and extrinsic atopic dermatitis: similarities and differences","volume":"15","author":"Liu","year":"2022","journal-title":"Clin. Cosmet. Invest. Dermatol."},{"key":"nanoad4bedbib6","doi-asserted-by":"publisher","first-page":"29","DOI":"10.52711\/0975-4377.2022.00005","article-title":"Review on antifungal agents","volume":"14","author":"Shirsat","year":"2022","journal-title":"Res. J. Pharm. Dosage Forms Technol."},{"key":"nanoad4bedbib7","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1099\/jmm.0.001318","article-title":"On the emergence, spread and resistance of Candida auris: host, pathogen and environmental tipping points","volume":"70","author":"Chakrabarti","year":"2021","journal-title":"J. Med. Microbiol."},{"key":"nanoad4bedbib8","author":"Attas","year":"2021"},{"key":"nanoad4bedbib9","first-page":"p 371","article-title":"Human fungal pathogens: diversity, genomics, and preventions","author":"Fahliyani","year":"2021"},{"key":"nanoad4bedbib10","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/j.idc.2021.03.007","article-title":"Candidemia and invasive candidiasis","volume":"35","author":"McCarty","year":"2021","journal-title":"Infect. Dis. Clin."},{"key":"nanoad4bedbib11","doi-asserted-by":"publisher","first-page":"e00029","DOI":"10.1128\/CMR.00029-17","article-title":"Candida auris: a review of the literature","volume":"31","author":"Jeffery-Smith","year":"2018","journal-title":"Clin. Microbiol. Rev."},{"key":"nanoad4bedbib12","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1111\/myc.12781","article-title":"An outbreak due to Candida auris with prolonged colonisation and candidaemia in a tertiary care European hospital","volume":"61","author":"Ruiz\u2010Gait\u00e1n","year":"2018","journal-title":"Mycoses"},{"key":"nanoad4bedbib13","first-page":"389","article-title":"Hemodialysis-associated infections","author":"Nguyen","year":"2019"},{"key":"nanoad4bedbib14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13756-016-0132-5","article-title":"First hospital outbreak of the globally emerging Candida auris in a European hospital","volume":"5","author":"Schelenz","year":"2016","journal-title":"Antimicrob. Resist. Infect. Control."},{"key":"nanoad4bedbib15","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1097\/QCO.0000000000000469","article-title":"Candida auris","volume":"31","author":"Saris","year":"2018","journal-title":"Curr. Opin. Infect. Dis."},{"key":"nanoad4bedbib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41426-018-0197-8","article-title":"First cases and risk factors of super yeast Candida auris infection or colonization from Shenyang, China","volume":"7","author":"Tian","year":"2018","journal-title":"Emerg. Microbes Infect."},{"key":"nanoad4bedbib17","doi-asserted-by":"publisher","first-page":"539","DOI":"10.3390\/antibiotics9090539","article-title":"Ibrexafungerp: a novel oral triterpenoid antifungal in development for the treatment of Candida auris infections","volume":"9","author":"Ghannoum","year":"2020","journal-title":"Antibiotics"},{"key":"nanoad4bedbib18","doi-asserted-by":"publisher","first-page":"A29","DOI":"10.1016\/j.ajic.2019.03.004","article-title":"New and emerging infectious diseases (ebola, middle eastern respiratory syndrome coronavirus, carbapenem-resistant enterobacteriaceae, Candida auris): focus on environmental survival and germicide susceptibility","volume":"47","author":"Weber","year":"2019","journal-title":"Am. J. Infect. Control"},{"key":"nanoad4bedbib19","volume":"vol 23","author":"Shaukat","year":"2021"},{"key":"nanoad4bedbib20","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1111\/myc.12754","article-title":"Comparative virulence of Candida auris with Candida haemulonii, Candida glabrata and Candida albicans in a murine model","volume":"61","author":"Fakhim","year":"2018","journal-title":"Mycoses"},{"key":"nanoad4bedbib21","doi-asserted-by":"publisher","first-page":"898","DOI":"10.3390\/antibiotics9120898","article-title":"Candida auris urinary tract infections and possible treatment","volume":"9","author":"Griffith","year":"2020","journal-title":"Antibiotics"},{"key":"nanoad4bedbib22","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.1056\/NEJMoa1714373","article-title":"A Candida auris outbreak and its control in an intensive care setting","volume":"379","author":"Eyre","year":"2018","journal-title":"New Engl. J. Med."},{"key":"nanoad4bedbib23","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1080\/14787210.2017.1364992","article-title":"Candida auris: a worrisome, globally emerging pathogen","volume":"15","author":"Navalkele","year":"2017","journal-title":"Expert Rev. Anti-Infect. Ther."},{"key":"nanoad4bedbib24","doi-asserted-by":"publisher","first-page":"1250","DOI":"10.3201\/eid2007.131765","article-title":"Candida auris\u2013associated candidemia, South Africa","volume":"20","author":"Magobo","year":"2014","journal-title":"Emerg. Infect. Dis."},{"key":"nanoad4bedbib25","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.mib.2019.05.008","article-title":"Global epidemiology of emerging Candida auris","volume":"52","author":"Rhodes","year":"2019","journal-title":"Curr. Opin. Microbiol."},{"key":"nanoad4bedbib26","doi-asserted-by":"publisher","first-page":"140","DOI":"10.3390\/jof7020140","article-title":"Molecular epidemiological investigation of a nosocomial cluster of C. auris: evidence of recent emergence in Italy and ease of transmission during the COVID-19 pandemic","volume":"7","author":"Pilato","year":"2021","journal-title":"J. Fungi"},{"key":"nanoad4bedbib27","doi-asserted-by":"publisher","first-page":"876","DOI":"10.3201\/eid2605.191588","article-title":"Clinical outcomes of patients treated for Candida auris infections in a multisite health system, Illinois, USA","volume":"26","author":"Arensman","year":"2020","journal-title":"Emerg. Infect. Dis."},{"key":"nanoad4bedbib28","doi-asserted-by":"publisher","first-page":"878","DOI":"10.3390\/jof7100878","article-title":"International multicentre study of Candida auris infections","volume":"7","author":"Pandya","year":"2021","journal-title":"J. Fungi"},{"key":"nanoad4bedbib29","doi-asserted-by":"publisher","first-page":"4470","DOI":"10.3390\/ijms22094470","article-title":"Candida auris: a quick review on identification, current treatments, and challenges","volume":"22","author":"\u010cern\u00e1kov\u00e1","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"nanoad4bedbib30","doi-asserted-by":"publisher","DOI":"10.1016\/j.fgb.2019.103243","article-title":"Candida auris and multidrug resistance: defining the new normal","volume":"131","author":"Lockhart","year":"2019","journal-title":"Fungal Genet. Biol."},{"key":"nanoad4bedbib31","doi-asserted-by":"publisher","first-page":"2445","DOI":"10.1128\/JCM.00630-17","article-title":"Rapid and accurate molecular identification of the emerging multidrug-resistant pathogen Candida auris","volume":"55","author":"Kordalewska","year":"2017","journal-title":"J. Clin. Microbiol."},{"key":"nanoad4bedbib32","doi-asserted-by":"publisher","first-page":"771","DOI":"10.2174\/1573405617666211208121419","article-title":"Use of ultrasound to observe mycosis fungoides: a case report and review of literature","volume":"18","author":"Chen","year":"2022","journal-title":"Curr. Med. Imaging"},{"key":"nanoad4bedbib33","doi-asserted-by":"publisher","first-page":"9782","DOI":"10.1021\/acs.jafc.3c02415","article-title":"Integrating genomics and metabolomics for the targeted discovery of new cyclopeptides with antifungal activity from a marine-derived fungus beauveria felina","volume":"71","author":"Jiang","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"nanoad4bedbib34","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1021\/acsinfecdis.3c00647","article-title":"Current development of thiazole-containing compounds as potential antibacterials against methicillin-resistant staphylococcus aureus","volume":"10","author":"Liu","year":"2024","journal-title":"ACS Infect. Dis."},{"key":"nanoad4bedbib35","doi-asserted-by":"publisher","first-page":"e02311","DOI":"10.1128\/spectrum.02311-22","article-title":"The bacterial MtrAB two-component system regulates the cell wall homeostasis responding to environmental alkaline stress","volume":"10","author":"Qin","year":"2022","journal-title":"Microbiol. Spectr."},{"key":"nanoad4bedbib36","doi-asserted-by":"publisher","first-page":"e00218","DOI":"10.1128\/msystems.00218-22","article-title":"Effects of \u2018healthy\u2019fecal microbiota transplantation against the deterioration of depression in fawn-hooded rats","volume":"7","author":"Hu","year":"2022","journal-title":"Msystems"},{"key":"nanoad4bedbib37","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.115387","article-title":"Babao Dan alleviates gut immune and microbiota disorders while impacting the TLR4\/MyD88\/NF-\u043aB pathway to attenuate 5-fluorouracil-induced intestinal injury","volume":"166","author":"Huang","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"nanoad4bedbib38","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1155\/2023\/9933283","article-title":"Niosome as an effective nanoscale solution for the treatment of microbial infections","volume":"2023","author":"Barani","year":"2023","journal-title":"Biomed. Res. Int."},{"key":"nanoad4bedbib39","article-title":"Advances of liposomal mediated nanocarriers for the treatment of dermatophyte infections","volume":"9","author":"Mousavi","year":"2023","journal-title":"Heliyon"},{"key":"nanoad4bedbib40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12645-023-00200-y","article-title":"Targeting nano-regulator based on metal\u2013organic frameworks for enhanced immunotherapy of bone metastatic prostate cancer","volume":"14","author":"Huang","year":"2023","journal-title":"Cancer Nanotechnol."},{"key":"nanoad4bedbib41","doi-asserted-by":"publisher","first-page":"707","DOI":"10.3390\/ph14080707","article-title":"Emerging applications of nanotechnology in healthcare systems: grand challenges and perspectives","volume":"14","author":"Anjum","year":"2021","journal-title":"Pharmaceuticals"},{"key":"nanoad4bedbib42","doi-asserted-by":"publisher","first-page":"2281","DOI":"10.1016\/j.nano.2017.06.015","article-title":"Nano-therapeutics: a revolution in infection control in post antibiotic era","volume":"13","author":"Zaidi","year":"2017","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"key":"nanoad4bedbib43","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.actatropica.2019.04.020","article-title":"Nano-facilitated drug delivery strategies in the treatment of plasmodium infection","volume":"195","author":"Puttappa","year":"2019","journal-title":"Acta Trop."},{"key":"nanoad4bedbib44","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtemb.2023.127325","article-title":"Green synthesis of Ag and Cu-doped Bismuth oxide nanoparticles: revealing synergistic antimicrobial and selective cytotoxic potentials for biomedical advancements","volume":"81","author":"Sarani","year":"2024","journal-title":"J. Trace Elem. Med. Biol."},{"key":"nanoad4bedbib45","doi-asserted-by":"publisher","DOI":"10.1049\/tje2.12268","article-title":"Inhibitory effect of zinc oxide nanoparticles and fibrillar chitosan\u2010zinc oxide nanostructures against herpes simplex virus infection","volume":"2023","author":"Abbasi","year":"2023","journal-title":"J. Eng."},{"key":"nanoad4bedbib46","doi-asserted-by":"publisher","first-page":"857","DOI":"10.2217\/nnm-2020-0482","article-title":"Nanotechnology approaches for delivery and targeting of Amphotericin B in fungal and parasitic diseases","volume":"16","author":"Jafari","year":"2021","journal-title":"Nanomedicine"},{"key":"nanoad4bedbib47","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.2217\/nnm-2020-0117","article-title":"Application of nanomaterials in treatment, anti-infection and detection of coronaviruses","volume":"15","author":"Nikaeen","year":"2020","journal-title":"Nanomedicine"},{"key":"nanoad4bedbib48","doi-asserted-by":"publisher","first-page":"881","DOI":"10.3390\/biology10090881","article-title":"Trends in nanotechnology and its potentialities to control plant pathogenic fungi: a review","volume":"10","author":"Kutawa","year":"2021","journal-title":"Biology"},{"key":"nanoad4bedbib49","doi-asserted-by":"publisher","first-page":"90","DOI":"10.2174\/2211738510666220210105113","article-title":"Theranostic applications of stimulusresponsive systems based on Fe2O3","volume":"10","author":"Pourmadadi","year":"2022","journal-title":"Pharm. Nanotechnol."},{"key":"nanoad4bedbib50","doi-asserted-by":"publisher","first-page":"182","DOI":"10.3390\/antiox10020182","article-title":"Phytogenic fabrication of Ag\u2013Fe bimetallic nanoparticles for cell cycle arrest and apoptosis signaling pathways in Candida auris by generating oxidative stress","volume":"10","author":"Kamli","year":"2021","journal-title":"Antioxidants"},{"key":"nanoad4bedbib51","doi-asserted-by":"publisher","first-page":"62","DOI":"10.3390\/jof7010062","article-title":"Facile bio-fabrication of Ag-Cu-Co trimetallic nanoparticles and its fungicidal activity against Candida auris","volume":"7","author":"Kamli","year":"2021","journal-title":"J. Fungi"},{"key":"nanoad4bedbib52","doi-asserted-by":"publisher","first-page":"180","DOI":"10.3390\/pharmaceutics14010180","article-title":"Nanostructured lipid carriers loaded with lippia sidoides essential oil as a strategy to combat the multidrug-resistant Candida auris","volume":"14","author":"Baldim","year":"2022","journal-title":"Pharmaceutics"},{"key":"nanoad4bedbib53","doi-asserted-by":"publisher","first-page":"21183","DOI":"10.1021\/acsami.9b20708","article-title":"Inhibition of Candida auris biofilm formation on medical and environmental surfaces by silver nanoparticles","volume":"12","author":"Lara","year":"2020","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"nanoad4bedbib54","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1021\/acsanm.1c01013","article-title":"Eradication of fungi using MoSe2\/chitosan nanosheets","volume":"5","author":"Saha","year":"2022","journal-title":"ACS Appl. Nano Mater."},{"key":"nanoad4bedbib55","doi-asserted-by":"publisher","first-page":"857","DOI":"10.3390\/microorganisms8060857","article-title":"Candida and candidiasis\u2014opportunism versus pathogenicity: a review of the virulence traits","volume":"8","author":"Ciurea","year":"2020","journal-title":"Microorganisms"},{"key":"nanoad4bedbib56","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1001127","article-title":"How many species are there on Earth and in the ocean?","volume":"9","author":"Mora","year":"2011","journal-title":"PLoS Biol."},{"key":"nanoad4bedbib57","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0101510","article-title":"Epidemiology and outcomes of invasive candidiasis due to non-albicans species of Candida in 2,496 patients: data from the prospective antifungal therapy (PATH) registry 2004\u20132008","volume":"9","author":"Pfaller","year":"2014","journal-title":"PLoS One"},{"key":"nanoad4bedbib58","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.diagmicrobio.2012.06.012","article-title":"The PATH (prospective antifungal therapy) alliance\u00ae registry and invasive fungal infections: update 2012","volume":"73","author":"Azie","year":"2012","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"nanoad4bedbib59","first-page":"21","article-title":"Virulence and pathogenicity of fungal pathogens with special reference to Candida albicans","author":"Khan","year":"2010"},{"key":"nanoad4bedbib60","first-page":"95","article-title":"Candida albicans: genetics, dimorphism and pathogenicity","volume":"1","author":"Molero","year":"1998","journal-title":"Int. Microbiol."},{"key":"nanoad4bedbib61","doi-asserted-by":"publisher","first-page":"67","DOI":"10.3390\/jof5030067","article-title":"Emerging fungal infections: new patients, new patterns, and new pathogens","volume":"5","author":"Friedman","year":"2019","journal-title":"J. Fungi"},{"key":"nanoad4bedbib62","doi-asserted-by":"publisher","first-page":"S445","DOI":"10.1093\/infdis\/jix131","article-title":"Multidrug-resistant Candida: epidemiology, molecular mechanisms, and treatment","volume":"216","author":"Arendrup","year":"2017","journal-title":"J. Infect. Dis."},{"key":"nanoad4bedbib63","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1016\/j.cmi.2021.11.024","article-title":"In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B resistance in Candida auris","volume":"28","author":"Rybak","year":"2022","journal-title":"Clin. Microbiol. Infect."},{"key":"nanoad4bedbib64","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1111\/myc.13477","article-title":"Drug repurposing against Candida auris: a systematic review","volume":"65","author":"Izadi","year":"2022","journal-title":"Mycoses"},{"key":"nanoad4bedbib65","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1111\/myc.13471","article-title":"Global prevalence and subgroup analyses of coronavirus disease (COVID-19) associated Candida auris infections (CACa): a systematic review and meta-analysis","volume":"65","author":"Vaseghi","year":"2022","journal-title":"Mycoses"},{"key":"nanoad4bedbib66","doi-asserted-by":"publisher","first-page":"1160","DOI":"10.1080\/22221751.2020.1771218","article-title":"Comparison of in vivo pathogenicity of four Candida auris clades in a neutropenic bloodstream infection murine model","volume":"9","author":"Forg\u00e1cs","year":"2020","journal-title":"Emerg. Microbes Infect."},{"key":"nanoad4bedbib67","first-page":"03364","article-title":"Tracing the evolutionary history and global expansion of Candida auris using population genomic analyses","volume":"11","author":"Chow","year":"2020","journal-title":"ASM"},{"key":"nanoad4bedbib68","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1111\/myc.13445","article-title":"Expert recommendations for prevention and management of Candida auris transmission","volume":"65","author":"Aldejohann","year":"2022","journal-title":"Mycoses"},{"key":"nanoad4bedbib69","doi-asserted-by":"publisher","first-page":"3390","DOI":"10.1021\/acs.chemrev.0c00199","article-title":"Antifungal drug resistance: molecular mechanisms in Candida albicans and beyond","volume":"121","author":"Lee","year":"2020","journal-title":"Chem. Rev."},{"key":"nanoad4bedbib70","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1038\/nchembio.1496","article-title":"Amphotericin forms an extramembranous and fungicidal sterol sponge","volume":"10","author":"Anderson","year":"2014","journal-title":"Nat. Chem. Biol."},{"key":"nanoad4bedbib71","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1007\/s40121-020-00382-7","article-title":"Sixty years of Amphotericin B: an overview of the main antifungal agent used to treat invasive fungal infections","volume":"10","author":"Cavassin","year":"2021","journal-title":"Infect. Dis. Ther."},{"key":"nanoad4bedbib72","doi-asserted-by":"publisher","first-page":"e383","DOI":"10.1016\/S1473-3099(17)30316-X","article-title":"The global problem of antifungal resistance: prevalence, mechanisms, and management","volume":"17","author":"Perlin","year":"2017","journal-title":"Lancet Infect. Dis."},{"key":"nanoad4bedbib73","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.jiac.2018.10.007","article-title":"Antifungal susceptibility trend and analysis of resistance mechanism for Candida species isolated from bloodstream at a Japanese university hospital","volume":"25","author":"Sakagami","year":"2019","journal-title":"J. Infect. Chemother."},{"key":"nanoad4bedbib74","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/204237","article-title":"Candida infections, causes, targets, and resistance mechanisms: traditional and alternative antifungal agents","volume":"2013","author":"Spampinato","year":"2013","journal-title":"Biomed Res. Int."},{"key":"nanoad4bedbib75","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1016\/j.cmi.2019.03.028","article-title":"Resistance of Candida to azoles and echinocandins worldwide","volume":"25","author":"Pristov","year":"2019","journal-title":"Clin. Microbiol. Infect."},{"key":"nanoad4bedbib76","doi-asserted-by":"publisher","first-page":"237","DOI":"10.2147\/IDR.S118892","article-title":"Fluconazole resistance in Candida species: a current perspective","volume":"10","author":"Berkow","year":"2017","journal-title":"Infect. Drug Resist."},{"key":"nanoad4bedbib77","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1093\/jac\/dkx480","article-title":"A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009\u201317) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance","volume":"73","author":"Chowdhary","year":"2018","journal-title":"J. Antimicrob. Chemother."},{"key":"nanoad4bedbib78","doi-asserted-by":"publisher","first-page":"a019703","DOI":"10.1101\/cshperspect.a019703","article-title":"Antifungal drug development: challenges, unmet clinical needs, and new approaches","volume":"4","author":"Roemer","year":"2014","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"nanoad4bedbib79","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.ijantimicag.2017.09.002","article-title":"The antifungal arsenal: alternative drugs and future targets","volume":"51","author":"Wiederhold","year":"2018","journal-title":"Int. J. Antimicrob. Agents"},{"key":"nanoad4bedbib80","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1111\/1469-0691.12038","article-title":"ESCMID* guideline for the diagnosis and management of Candida diseases 2012: diagnostic procedures","volume":"18","author":"Cuenca-Estrella","year":"2012","journal-title":"Clin. Microbiol. Infect."},{"key":"nanoad4bedbib81","doi-asserted-by":"crossref","first-page":"312","DOI":"10.3390\/antibiotics9060312","article-title":"Candidiasis and mechanisms of antifungal resistance","volume":"9","author":"Bhattacharya","year":"2020","journal-title":"Antibiotics"},{"key":"nanoad4bedbib82","doi-asserted-by":"publisher","first-page":"1635","DOI":"10.1111\/jphp.12780","article-title":"Echinocandins in antifungal pharmacotherapy","volume":"69","author":"Patil","year":"2017","journal-title":"J. Pharm. Pharmacol."},{"key":"nanoad4bedbib83","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1016\/S0140-6736(03)14472-8","article-title":"Echinocandin antifungal drugs","volume":"362","author":"Denning","year":"2003","journal-title":"Lancet"},{"key":"nanoad4bedbib84","doi-asserted-by":"publisher","first-page":"2435","DOI":"10.1128\/AAC.06369-11","article-title":"Differential in vivo activities of anidulafungin, caspofungin, and micafungin against Candida glabrata isolates with and without FKS resistance mutations","volume":"56","author":"Arendrup","year":"2012","journal-title":"Antimicrob. Agents Chemother."},{"key":"nanoad4bedbib85","doi-asserted-by":"publisher","first-page":"3550","DOI":"10.1128\/AAC.02367-14","article-title":"Echinocandin failure case due to a previously unreported FKS1 mutation in Candida krusei","volume":"58","author":"Jensen","year":"2014","journal-title":"Antimicrob. Agents Chemother."},{"key":"nanoad4bedbib86","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1128\/AAC.02265-15","article-title":"Acquired flucytosine resistance during combination therapy with caspofungin and flucytosine for Candida glabrata cystitis","volume":"60","author":"Charlier","year":"2016","journal-title":"Antimicrob. Agents Chemother."},{"key":"nanoad4bedbib87","doi-asserted-by":"publisher","first-page":"3101","DOI":"10.1128\/AAC.49.8.3101-3108.2005","article-title":"Inactivation of the FCY2 gene encoding purine-cytosine permease promotes cross-resistance to flucytosine and fluconazole in Candida lusitaniae","volume":"49","author":"Chapeland-Leclerc","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"key":"nanoad4bedbib88","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0135110","article-title":"New mechanisms of flucytosine resistance in C. glabrata unveiled by a chemogenomics analysis in S. cerevisiae","volume":"10","author":"Costa","year":"2015","journal-title":"PLoS One"},{"key":"nanoad4bedbib89","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3390\/jof6010023","article-title":"An overview on conventional and non-conventional therapeutic approaches for the treatment of candidiasis and underlying resistance mechanisms in clinical strains","volume":"6","author":"Salazar","year":"2020","journal-title":"J. Fungi"},{"key":"nanoad4bedbib90","doi-asserted-by":"publisher","first-page":"771","DOI":"10.3390\/ijms22020771","article-title":"The Neosartorya fischeri antifungal protein 2 (NFAP2): a new potential weapon against multidrug-resistant Candida auris biofilms","volume":"22","author":"Kov\u00e1cs","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"nanoad4bedbib91","doi-asserted-by":"publisher","first-page":"1308","DOI":"10.1111\/myc.13277","article-title":"New weapons to fight a new enemy: a systematic review of drug combinations against the drug\u2010resistant fungus Candida auris","volume":"64","author":"Aghaei Gharehbolagh","year":"2021","journal-title":"Mycoses"},{"key":"nanoad4bedbib92","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1049\/iet-nbt.2017.0025","article-title":"Evaluation of antifungal effect of iron\u2010oxide nanoparticles against different Candida species","volume":"11","author":"Seddighi","year":"2017","journal-title":"IET Nanobiotechnol."},{"key":"nanoad4bedbib93","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11274-020-02940-0","article-title":"The use of nanoparticles as alternative therapeutic agents against Candida infections: an up-to-date overview and future perspectives","volume":"36","author":"Mba","year":"2020","journal-title":"World J. Microbiol. Biotechnol."},{"key":"nanoad4bedbib94","first-page":"347","article-title":"Antimicrobial effect of copper oxide nanoparticles on some oral bacteria and Candida species","volume":"4","author":"Amiri","year":"2017","journal-title":"J. Dent. Biomater."},{"key":"nanoad4bedbib95","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2022.103302","article-title":"The convergence of in silico approach and nanomedicine for efficient cancer treatment; in vitro investigations on curcumin loaded multifunctional graphene oxide nanocomposite structure","volume":"71","author":"Paknia","year":"2022","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"nanoad4bedbib96","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1177\/0022034510377794","article-title":"The use of nanoparticles to control oral biofilm formation","volume":"89","author":"Allaker","year":"2010","journal-title":"J. Dent. Res."},{"key":"nanoad4bedbib97","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2021.102397","article-title":"Lipid based nanocarriers: a novel paradigm for topical antifungal therapy","volume":"62","author":"Nene","year":"2021","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"nanoad4bedbib98","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1007\/s40199-019-00277-0","article-title":"Diosgenin-loaded niosome as an effective phytochemical nanocarrier: physicochemical characterization, loading efficiency, and cytotoxicity assay","volume":"27","author":"Hajizadeh","year":"2019","journal-title":"DARU J. Pharma. Sci."},{"key":"nanoad4bedbib99","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemphyslip.2020.104953","article-title":"Amelioration of ketoconazole in lipid nanoparticles for enhanced antifungal activity and bioavailability through oral administration for management of fungal infections","volume":"232","author":"Dudhipala","year":"2020","journal-title":"Chem. Phys. Lipids"},{"key":"nanoad4bedbib100","doi-asserted-by":"publisher","first-page":"2052","DOI":"10.3389\/fmicb.2020.02052","article-title":"Antifungal photodynamic activity of hexyl-aminolevulinate ethosomes against Candida albicans biofilm","volume":"11","author":"Wang","year":"2020","journal-title":"Front. Microbiol."},{"key":"nanoad4bedbib101","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1016\/j.colsurfb.2016.03.013","article-title":"Time to overcome fluconazole resistant Candida isolates: solid lipid nanoparticles as a novel antifungal drug delivery system","volume":"142","author":"Moazeni","year":"2016","journal-title":"Colloids Surf. B"},{"key":"nanoad4bedbib102","doi-asserted-by":"publisher","first-page":"884","DOI":"10.3390\/pharmaceutics13060884","article-title":"Recent advances in polymer-based vaginal drug delivery systems","volume":"13","author":"Osma\u0142ek","year":"2021","journal-title":"Pharmaceutics"},{"key":"nanoad4bedbib103","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.ejpb.2016.12.029","article-title":"PEGylated liposomes for topical vaginal therapy improve delivery of interferon alpha","volume":"113","author":"J\u00f8raholmen","year":"2017","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"nanoad4bedbib104","doi-asserted-by":"publisher","DOI":"10.1016\/j.nanoso.2019.100397","article-title":"Recent developments in functionalized polymer nanoparticles for efficient drug delivery system","volume":"20","author":"Sur","year":"2019","journal-title":"Nano-Struct. Nano-Objects"},{"key":"nanoad4bedbib105","doi-asserted-by":"publisher","first-page":"5187","DOI":"10.2147\/IJN.S205350","article-title":"Alginate nanoparticles as non-toxic delivery system for miltefosine in the treatment of candidiasis and cryptococcosis","volume":"14","author":"de Castro Spadari","year":"2019","journal-title":"Int. J. Nanomed."},{"key":"nanoad4bedbib106","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1093\/mmy\/myx155","article-title":"Development, characterization, and in vitro\u2013in vivo evaluation of polymeric nanoparticles containing miconazole and farnesol for treatment of vulvovaginal candidiasis","volume":"57","author":"Fernandes Costa","year":"2019","journal-title":"Med. Mycol."},{"key":"nanoad4bedbib107","doi-asserted-by":"publisher","first-page":"279","DOI":"10.3390\/md18060279","article-title":"Natural cyanobacterial polymer-based coating as a preventive strategy to avoid catheter-associated urinary tract infections","volume":"18","author":"Costa","year":"2020","journal-title":"Mar. Drugs"},{"key":"nanoad4bedbib108","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1016\/j.nanoso.2018.08.001","article-title":"Activated carbon nanoparticles from biowaste as new generation antimicrobial agents: a review","volume":"16","author":"Lakshmi","year":"2018","journal-title":"Nano-Struct. Nano-Objects"},{"key":"nanoad4bedbib109","doi-asserted-by":"publisher","first-page":"19","DOI":"10.5681\/apb.2015.003","article-title":"Antimicrobial activity of carbon-based nanoparticles","volume":"5","author":"Dizaj","year":"2015","journal-title":"Adv. Pharm. Bull."},{"key":"nanoad4bedbib110","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.jobcr.2020.04.012","article-title":"Evaluation of nanomaterials to prevent oral Candidiasis in PMMA based denture wearing patients. A systematic analysis","volume":"10","author":"Ahmad","year":"2020","journal-title":"J. Oral Biol. Craniofac. Res."},{"key":"nanoad4bedbib111","doi-asserted-by":"publisher","DOI":"10.1016\/j.cis.2020.102250","article-title":"Carbon nanomaterials against pathogens; the antimicrobial activity of carbon nanotubes, graphene\/graphene oxide, fullerenes, and their nanocomposites","volume":"284","author":"Azizi-Lalabadi","year":"2020","journal-title":"Adv. Colloid Interface Sci."},{"key":"nanoad4bedbib112","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1007\/s40204-019-0109-6","article-title":"A new formulation of graphene oxide\/fluconazole compound as a promising agent against Candida albicans","volume":"8","author":"Asadi Shahi","year":"2019","journal-title":"Prog. Biomater."},{"key":"nanoad4bedbib113","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1021\/nn1023522","article-title":"Antifungal activity of amphotericin B conjugated to carbon nanotubes","volume":"5","author":"Benincasa","year":"2011","journal-title":"ACS Nano"},{"key":"nanoad4bedbib114","first-page":"287","article-title":"Metal oxide\u2013based nanocomposites as antimicrobial and biomedical agents","author":"Owonubi","year":"2020"},{"key":"nanoad4bedbib115","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1021\/acsbiomaterials.7b00511","article-title":"High antifungal activity against candida species of monometallic and bimetallic nanoparticles synthesized in nanoreactors","volume":"4","author":"Guti\u00e9rrez","year":"2018","journal-title":"ACS Biomater. Sci. Eng."},{"key":"nanoad4bedbib116","doi-asserted-by":"publisher","first-page":"4667","DOI":"10.2147\/IJN.S210449","article-title":"Anticandidal activity of biosynthesized silver nanoparticles: effect on growth, cell morphology, and key virulence attributes of Candida species","volume":"14","author":"Jalal","year":"2019","journal-title":"Int. J. Nanomed."},{"key":"nanoad4bedbib117","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12951-015-0147-8","article-title":"Effect of silver nanoparticles on Candida albicans biofilms: an ultrastructural study","volume":"13","author":"Lara","year":"2015","journal-title":"J. Nanobiotechnol."},{"key":"nanoad4bedbib118","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.materresbull.2012.09.069","article-title":"Antifungal activity of gold nanoparticles prepared by solvothermal method","volume":"48","author":"Ahmad","year":"2013","journal-title":"Mater. Res. Bull."},{"key":"nanoad4bedbib119","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.micres.2017.11.003","article-title":"Reactive oxygen species-independent apoptotic pathway by gold nanoparticles in Candida albicans","volume":"207","author":"Seong","year":"2018","journal-title":"Microbiol. Res."},{"key":"nanoad4bedbib120","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1016\/j.ceramint.2014.09.016","article-title":"Synthesis of zinc oxide nanoparticles by homogeneous precipitation method and its application in antifungal activity against Candida albicans","volume":"41","author":"Sharma","year":"2015","journal-title":"Ceram. Int."},{"key":"nanoad4bedbib121","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1080\/17518253.2020.1717005","article-title":"Cytotoxic and antifungal studies of biosynthesized zinc oxide nanoparticles using extract of Prosopis farcta fruit","volume":"13","author":"Miri","year":"2020","journal-title":"Green Chem. Lett. Rev."},{"key":"nanoad4bedbib122","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2019.109981","article-title":"Zinc oxide nanoparticles: biosynthesis, characterization, antifungal and cytotoxic activity","volume":"104","author":"Miri","year":"2019","journal-title":"Mater. Sci. Eng. C"},{"key":"nanoad4bedbib123","doi-asserted-by":"publisher","first-page":"1281","DOI":"10.1016\/j.ijbiomac.2017.11.046","article-title":"Synthesis, characterization of ZnO-chitosan nanocomposites and evaluation of its antifungal activity against pathogenic Candida albicans","volume":"108","author":"Dananjaya","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"key":"nanoad4bedbib124","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclepro.2019.119085","article-title":"Sustainably produced cashew gum-capped zinc oxide nanoparticles show antifungal activity against Candida parapsilosis","volume":"247","author":"Souza","year":"2020","journal-title":"J. Clean. Prod."},{"key":"nanoad4bedbib125","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.matlet.2011.12.055","article-title":"Synthesis and antimicrobial activity of copper nanoparticles","volume":"71","author":"Ramyadevi","year":"2012","journal-title":"Mater. Lett."},{"key":"nanoad4bedbib126","doi-asserted-by":"publisher","first-page":"e5465","DOI":"10.1002\/aoc.5465","article-title":"Application of copper nanoparticles containing natural compounds in the treatment of bacterial and fungal diseases","volume":"34","author":"Hemmati","year":"2020","journal-title":"Appl. Organomet. Chem."},{"key":"nanoad4bedbib127","first-page":"21","article-title":"Effect of biosynthesized copper nanoparticles (CUNPS) on the growth and biofilm formation of fluconazole-resistant Candida albicans","volume":"2021","author":"Rasool","year":"2021","journal-title":"J. Microbiol. Biotechnol. Food Sci."},{"key":"nanoad4bedbib128","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.3390\/pharmaceutics13111957","article-title":"Beta vulgaris assisted fabrication of novel Ag-Cu bimetallic nanoparticles for growth inhibition and virulence in Candida albicans","volume":"13","author":"Kamli","year":"2021","journal-title":"Pharmaceutics"},{"key":"nanoad4bedbib129","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/srep36403","article-title":"Understanding the antifungal mechanism of Ag@ ZnO core-shell nanocomposites against Candida krusei","volume":"6","author":"Das","year":"2016","journal-title":"Sci. Rep."},{"key":"nanoad4bedbib130","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1093\/mmy\/myw053","article-title":"Chitosan silver nanocomposite (CAgNC) as an antifungal agent against Candida albicans","volume":"55","author":"Kulatunga","year":"2017","journal-title":"Med. Mycol."},{"key":"nanoad4bedbib131","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1007\/s40097-020-00331-3","article-title":"Antimicrobial effect of chitosan\u2013silver\u2013copper nanocomposite on Candida albicans","volume":"10","author":"Ashrafi","year":"2020","journal-title":"J. Nanostruct. Chem."},{"key":"nanoad4bedbib132","first-page":"1","article-title":"Optimized synthesis of xanthan gum\/ZnO\/TiO2 nanocomposite with high antifungal activity against pathogenic Candida albicans","volume":"2022","author":"Ghorbani","year":"2022","journal-title":"J. Nanometer."},{"key":"nanoad4bedbib133","doi-asserted-by":"publisher","first-page":"76718","DOI":"10.1039\/C5RA13316E","article-title":"Reactive oxygen species (ROS) mediated enhanced anti-candidal activity of ZnS\u2013ZnO nanocomposites with low inhibitory concentrations","volume":"5","author":"Suyana","year":"2015","journal-title":"RSC Adv."},{"key":"nanoad4bedbib134","doi-asserted-by":"publisher","DOI":"10.1016\/j.inoche.2021.109082","article-title":"Comparative studies of the biological efficacies of Ag and Ag-MgO nanocomposite formed by the green synthesis route","volume":"135","author":"Sagadevan","year":"2022","journal-title":"Inorg. Chem. Commun."},{"key":"nanoad4bedbib135","doi-asserted-by":"publisher","first-page":"3965","DOI":"10.2147\/IJN.S161002","article-title":"Modified magnetic nanoparticles by PEG-400-immobilized Ag nanoparticles (Fe3O4@ PEG\u2013Ag) as a core\/shell nanocomposite and evaluation of its antimicrobial activity","volume":"13","author":"Zomorodian","year":"2018","journal-title":"Int. J. Nanomed."},{"key":"nanoad4bedbib136","first-page":"285","article-title":"Mesoporous silica-based nano drug-delivery system synthesis, characterization, and applications","author":"Ghosh","year":"2019"},{"key":"nanoad4bedbib137","doi-asserted-by":"publisher","DOI":"10.1016\/j.sciaf.2018.e00007","article-title":"Antimicrobial photodynamic inactivation of fungal biofilm using amino functionalized mesoporus silica-rose bengal nanoconjugate against Candida albicans","volume":"1","author":"Paramanantham","year":"2018","journal-title":"Sci Afr."},{"key":"nanoad4bedbib138","doi-asserted-by":"crossref","DOI":"10.3389\/fchem.2022.836678","article-title":"Enhanced antifungal and wound healing efficacy of statistically optimized, physicochemically evaluated econazole-triamcinolone loaded silica nanoparticles","volume":"10","author":"Maheen","year":"2022","journal-title":"Front. Chem."},{"key":"nanoad4bedbib139","doi-asserted-by":"publisher","first-page":"639","DOI":"10.3390\/jof8060639","article-title":"Polyphenol-capped biogenic synthesis of noble metallic silver nanoparticles for antifungal activity against Candida auris","volume":"8","author":"Malik","year":"2022","journal-title":"J. Fungi"},{"key":"nanoad4bedbib140","doi-asserted-by":"publisher","first-page":"461","DOI":"10.3390\/antibiotics9080461","article-title":"Bismuth nanoantibiotics display anticandidal activity and disrupt the biofilm and cell morphology of the emergent pathogenic yeast Candida auris","volume":"9","author":"Vazquez-Munoz","year":"2020","journal-title":"Antibiotics"},{"key":"nanoad4bedbib141","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2020.106049","article-title":"Miltefosine as an alternative strategy in the treatment of the emerging fungus Candida auris","volume":"56","author":"Barreto","year":"2020","journal-title":"Int. J. Antimicrob. Agents"},{"key":"nanoad4bedbib142","doi-asserted-by":"publisher","first-page":"e00306","DOI":"10.1128\/AAC.00306-21","article-title":"In vitro and in vivo antifungal activity of ambisome compared to conventional amphotericin B and fluconazole against Candida auris","volume":"65","author":"Herrada","year":"2021","journal-title":"Antimicrob. Agents Chemother."},{"key":"nanoad4bedbib143","doi-asserted-by":"publisher","first-page":"2193","DOI":"10.1021\/acs.jmedchem.6b01203","article-title":"Tackling fungal resistance by biofilm inhibitors","volume":"60","author":"Wu","year":"2017","journal-title":"J. Med. Chem."},{"key":"nanoad4bedbib144","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1146\/annurev.med.59.110106.132000","article-title":"Bacterial and fungal biofilm infections","volume":"59","author":"Lynch","year":"2008","journal-title":"Annu. Rev. Med."},{"key":"nanoad4bedbib145","doi-asserted-by":"publisher","first-page":"5385","DOI":"10.1128\/JB.183.18.5385-5394.2001","article-title":"Biofilm formation by the fungal pathogen Candida albicans: development, architecture, and drug resistance","volume":"183","author":"Chandra","year":"2001","journal-title":"J. Bacteriol."},{"key":"nanoad4bedbib146","first-page":"175","article-title":"Photodynamic therapy of bacterial and fungal biofilm infections","author":"Biel","year":"2010"},{"key":"nanoad4bedbib147","doi-asserted-by":"publisher","first-page":"8873","DOI":"10.3390\/ijms21228873","article-title":"Combination therapy to treat fungal biofilm-based infections","volume":"21","author":"Tits","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"nanoad4bedbib148","author":"Richardson","year":"2012"},{"key":"nanoad4bedbib149","doi-asserted-by":"crossref","first-page":"42","DOI":"10.2174\/1871526515666150320162036","article-title":"Candidiasis: a fungal infection-current challenges and progress in prevention and treatment","volume":"15","author":"Hani","year":"2015","journal-title":"Infect. Disord. Drug Targets"},{"key":"nanoad4bedbib150","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1111\/j.1600-0609.2009.01391.x","article-title":"Diagnostic challenges and recent advances in the early management of invasive fungal infections","volume":"84","author":"Chandrasekar","year":"2010","journal-title":"Eur. J. Haematol."},{"key":"nanoad4bedbib151","doi-asserted-by":"publisher","first-page":"171","DOI":"10.4103\/INJMS.INJMS_32_20","article-title":"Challenges in fungal treatment: a serious public health problem","volume":"11","author":"Al-Khikani","year":"2020","journal-title":"Indian J. Med. Spec."},{"key":"nanoad4bedbib152","doi-asserted-by":"publisher","first-page":"2647","DOI":"10.2147\/IJN.S150648","article-title":"Silver nanoparticles induced alterations in multiple cellular targets, which are critical for drug susceptibilities and pathogenicity in fungal pathogen (Candida albicans)","volume":"13","author":"Radhakrishnan","year":"2018","journal-title":"Int. J. Nanomed."},{"key":"nanoad4bedbib153","doi-asserted-by":"publisher","first-page":"248","DOI":"10.3390\/ph13090248","article-title":"Current insights on antifungal therapy: novel nanotechnology approaches for drug delivery systems and new drugs from natural sources","volume":"13","author":"Sousa","year":"2020","journal-title":"Pharmaceuticals"},{"key":"nanoad4bedbib154","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.ijpharm.2017.03.019","article-title":"Nanoparticles as safe and effective delivery systems of antifungal agents: achievements and challenges","volume":"523","author":"Soliman","year":"2017","journal-title":"Int. J. Pharm."},{"key":"nanoad4bedbib155","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.2217\/fmb.13.101","article-title":"Mechanisms of Candida biofilm drug resistance","volume":"8","author":"Taff","year":"2013","journal-title":"Future Microbiol."},{"key":"nanoad4bedbib156","doi-asserted-by":"publisher","first-page":"1891","DOI":"10.2217\/nnm-2017-0052","article-title":"Development of antifungal therapies using nanomaterials","volume":"12","author":"Niemirowicz","year":"2017","journal-title":"Nanomedicine"},{"key":"nanoad4bedbib157","doi-asserted-by":"publisher","first-page":"639","DOI":"10.4155\/tde-2016-0040","article-title":"Solid lipid nanoparticles for antifungal drugs delivery for topical applications","volume":"7","author":"Trombino","year":"2016","journal-title":"Ther. Deliv."},{"key":"nanoad4bedbib158","doi-asserted-by":"publisher","first-page":"443","DOI":"10.3109\/10717544.2010.483252","article-title":"Design and development of solid lipid nanoparticles for topical delivery of an anti-fungal agent","volume":"17","author":"Jain","year":"2010","journal-title":"Drug Deliv."},{"key":"nanoad4bedbib159","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1208\/s12249-020-01717-w","article-title":"Preparation and characterization of nanostructured lipid carriers for improved topical drug delivery: evaluation in cutaneous leishmaniasis and vaginal candidiasis animal models","volume":"21","author":"Riaz","year":"2020","journal-title":"AAPS Pharm. Sci. Tech."},{"key":"nanoad4bedbib160","doi-asserted-by":"publisher","first-page":"433","DOI":"10.2174\/1381612023395916","article-title":"Drug delivery system of anti-fungal and parasitic agents","volume":"8","author":"Maesaki","year":"2002","journal-title":"Curr. Pharm. Des."},{"key":"nanoad4bedbib161","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11095-021-03162-1","article-title":"Meta-analysis of drug delivery approaches for treating intracellular infections","volume":"39","author":"Chang","year":"2022","journal-title":"Pharm. Res."}],"container-title":["Nanotechnology"],"original-title":[],"link":[{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/ad4bed","content-type":"text\/html","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/ad4bed\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/ad4bed","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/ad4bed\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/ad4bed\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/ad4bed\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/ad4bed\/pdf","content-type":"application\/pdf","content-version":"am","intended-application":"similarity-checking"},{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/ad4bed\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,14]],"date-time":"2025-06-14T14:41:54Z","timestamp":1749912114000},"score":1,"resource":{"primary":{"URL":"https:\/\/iopscience.iop.org\/article\/10.1088\/1361-6528\/ad4bed"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,30]]},"references-count":161,"journal-issue":{"issue":"33","published-online":{"date-parts":[[2024,5,30]]},"published-print":{"date-parts":[[2024,8,12]]}},"URL":"https:\/\/doi.org\/10.1088\/1361-6528\/ad4bed","relation":{},"ISSN":["0957-4484","1361-6528"],"issn-type":[{"value":"0957-4484","type":"print"},{"value":"1361-6528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,30]]},"assertion":[{"value":"Advancements in nanoparticle-based therapies for multidrug-resistant candidiasis infections: a comprehensive review","name":"article_title","label":"Article Title"},{"value":"Nanotechnology","name":"journal_title","label":"Journal Title"},{"value":"paper","name":"article_type","label":"Article Type"},{"value":"\u00a9 2024 IOP Publishing Ltd. All rights, including for text and data mining, AI training, and similar technologies, are reserved.","name":"copyright_information","label":"Copyright Information"},{"value":"2023-10-08","name":"date_received","label":"Date Received","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2024-05-15","name":"date_accepted","label":"Date Accepted","group":{"name":"publication_dates","label":"Publication dates"}},{"value":"2024-05-30","name":"date_epub","label":"Online publication date","group":{"name":"publication_dates","label":"Publication dates"}}]}}